Cognitive dysfunction and prefrontal synaptic abnormalities in a mouse model of fragile X syndrome - Wikidata - awgldk - TriplyDB

Cognitive dysfunction and prefrontal synaptic abnormalities in a mouse model of fragile X syndrome

Cognitive dysfunction and prefrontal synaptic abnormalities in a mouse model of fragile X syndrome

http://www.wikidata.org/entity/Q34573192

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Conceptualizing neurodevelopmental disorders through a mechanistic understanding of fragile X syndrome and Williams syndrome Striatal Circuits as a Common Node for Autism Pathophysiology Molecular underpinnings of prefrontal cortex development in rodents provide insights into the etiology of neurodevelopmental disorders Learning and behavioral deficits associated with the absence of the fragile X mental retardation protein: what a fly and mouse model can teach us.Neuroligins provide molecular links between syndromic and nonsyndromic autism Targeted pharmacological treatment of autism spectrum disorders: fragile X and Rett syndromes Therapeutic Strategies in Fragile X Syndrome: From Bench to Bedside and Back Neuronal Kmt2a/Mll1 histone methyltransferase is essential for prefrontal synaptic plasticity and working memory Impaired Dendritic Development and Memory in Sorbs2 Knock-Out Mice.Normal Performance of Fmr1 Mice on a Touchscreen Delayed Nonmatching to Position Working Memory Task From FMRP function to potential therapies for fragile X syndrome.Modeling fragile X syndrome in the Fmr1 knockout mouse Mice with reduced NMDA receptor expression: more consistent with autism than schizophrenia?Comprehensive neurocognitive endophenotyping strategies for mouse models of genetic disorders Hyperactivity, perseveration and increased responding during attentional rule acquisition in the Fragile X mouse model Impaired cognitive discrimination and discoordination of coupled theta-gamma oscillations in Fmr1 knockout mice.Extinction of an instrumental response: a cognitive behavioral assay in Fmr1 knockout mice.Fragile X syndrome: an update on developing treatment modalities.Increasing our understanding of human cognition through the study of Fragile X Syndrome.Reduced phenotypic severity following adeno-associated virus-mediated Fmr1 gene delivery in fragile X mice.Changes in sensitivity of reward and motor behavior to dopaminergic, glutamatergic, and cholinergic drugs in a mouse model of fragile X syndrome Functional and structural deficits at accumbens synapses in a mouse model of Fragile X.Visual sensorial impairments in neurodevelopmental disorders: evidence for a retinal phenotype in Fragile X Syndrome Aberrant frontal lobe maturation in adolescents with fragile X syndrome is related to delayed cognitive maturation Glycogen synthase kinase-3: a promising therapeutic target for fragile x syndrome Therapeutic strategies in fragile X syndrome: dysregulated mGluR signaling and beyond.Inhibition of GSK3β improves hippocampus-dependent learning and rescues neurogenesis in a mouse model of fragile X syndrome In vivo neuronal function of the fragile X mental retardation protein is regulated by phosphorylation Impaired survival of neural progenitor cells in dentate gyrus of adult mice lacking fMRP Mitochondria-targeted catalase reduces abnormal APP processing, amyloid β production and BACE1 in a mouse model of Alzheimer's disease: implications for neuroprotection and lifespan extension.Synaptic NMDA receptor-mediated currents in anterior piriform cortex are reduced in the adult fragile X mouse Group I mGluR antagonist rescues the deficit of D1-induced LTP in a mouse model of fragile X syndrome.Group I metabotropic glutamate receptor-mediated gene transcription and implications for synaptic plasticity and diseases.Dynamic regulation of synaptic maturation state by voltage-gated A-type K+ channels in CA1 hippocampal pyramidal neurons.Neuroligin-2 and the tightrope of excitation/inhibition balance in the prefrontal cortex Modeling neurodevelopmental cognitive deficits in tasks with cross-species translational validity Effects of stimulus salience on touchscreen serial reversal learning in a mouse model of fragile X syndrome.Altered structural and functional synaptic plasticity with motor skill learning in a mouse model of fragile X syndrome.Late onset deficits in synaptic plasticity in the valproic acid rat model of autism The role of ionotropic glutamate receptors in childhood neurodevelopmental disorders: autism spectrum disorders and fragile x syndrome.

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Cognitive dysfunction and prefrontal synaptic abnormalities in a mouse model of fragile X syndrome

http://www.wikidata.org/entity/Q34573192

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Cognitive dysfunction and pref ...... se model of fragile X syndrome

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Lynne D Tye

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Mark F Bear

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Stephanie P Chen

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P2860

Correction of fragile X syndrome in mice.

The Autistic Neuron: Troubled Translation?

Altered synaptic plasticity in a mouse model of fragile X mental retardation

Fragile X syndrome: loss of local mRNA regulation alters synaptic development and function

Cortico-striatal synaptic defects and OCD-like behaviours in Sapap3-mutant mice.

Abnormal dendritic spines in fragile X knockout mice: maturation and pruning deficits

A new function for the fragile X mental retardation protein in regulation of PSD-95 mRNA stability

Roles of fragile X mental retardation protein in dopaminergic stimulation-induced synapse-associated protein synthesis and subsequent alpha-amino-3-hydroxyl-5-methyl-4-isoxazole-4-propionate (AMPA) receptor internalization

Regulation of synaptic structure and function by FMRP-associated microRNAs miR-125b and miR-132

Elongation factor 2 and fragile X mental retardation protein control the dynamic translation of Arc/Arg3.1 essential for mGluR-LTD

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