Organic anion transporting polypeptide 2B1 is a high-affinity transporter for atorvastatin and is expressed in the human heart.
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Role of Organic Anion-Transporting Polypeptides (OATPs) in Cancer TherapyOATPs, OATs and OCTs: the organic anion and cation transporters of the SLCO and SLC22A gene superfamiliesRapid modulation of the organic anion transporting polypeptide 2B1 (OATP2B1, SLCO2B1) function by protein kinase C-mediated internalization.H+-coupled nutrient, micronutrient and drug transporters in the mammalian small intestineXenobiotic, bile acid, and cholesterol transporters: function and regulation.Mechanism of polybrominated diphenyl ether uptake into the liver: PBDE congeners are substrates of human hepatic OATP transportersA systems biology approach to dynamic modeling and inter-subject variability of statin pharmacokinetics in human hepatocytes.Genetic variation in drug transporters in ethnic populations.The SLCO (former SLC21) superfamily of transporters.Impact of OATP transporters on pharmacokinetics.Pharmacogenetic Foundations of Therapeutic Efficacy and Adverse Events of Statins.Selective regulation of cardiac organic cation transporter novel type 2 (OCTN2) in dilated cardiomyopathyOrganic anion transporting polypeptides in the hepatic uptake of PBDE congeners in miceThe expression and function of organic anion transporting polypeptides in normal tissues and in cancerSubstrate- and pH-specific antifolate transport mediated by organic anion-transporting polypeptide 2B1 (OATP2B1-SLCO2B1)Pharmacokinetic interaction study of sulphasalazine in healthy subjects and the impact of curcumin as an in vivo inhibitor of BCRP.Targeted drug delivery to treat pain and cerebral hypoxiaInteraction of silymarin flavonolignans with organic anion-transporting polypeptides.Involvement of organic anion transporting polypeptides in the toxicity of hydrophilic pravastatin and lipophilic fluvastatin in rat skeletal myofibres.Transporter-mediated uptake into cellular compartments.Role of OATP transporters in the disposition of drugs.Absorption of montelukast is transporter mediated: a common variant of OATP2B1 is associated with reduced plasma concentrations and poor response.Effects of selected OATP and/or ABC transporter inhibitors on the brain and whole-body distribution of glyburide.siRNA capsulated brain-targeted nanoparticles specifically knock down OATP2B1 in mice: a mechanism for acute morphine tolerance suppressionImpact of cholesterol on ABC and SLC transporters expression and function and its role in disposition variability to lipid-lowering drugs.Statin regulation of CYP3A4 and CYP3A5 expression.The role of transporters in the pharmacokinetics of orally administered drugs.Transporter pharmacogenetics and statin toxicity.Hepatic OATP and OCT uptake transporters: their role for drug-drug interactions and pharmacogenetic aspects.Efflux and uptake transporters as determinants of statin response.Pharmacogenetics of drug-induced liver injury.Transporters, Trojan horses and therapeutics: suitability of bile acid and peptide transporters for drug delivery.Transporter-mediated drug-drug interactions.Functional characterization of drug uptake and metabolism in the heart.Current understanding of hepatic and intestinal OATP-mediated drug-drug interactions.Intestinal transporters for endogenic and pharmaceutical organic anions: the challenges of deriving in-vitro kinetic parameters for the prediction of clinically relevant drug-drug interactions.Transporter-mediated drug-drug interactions with oral antidiabetic drugs.Putative roles of organic anion transporting polypeptides (OATPs) in cell survival and progression of human cancers.Tissue thyroid hormones and thyronamines.Biodegradable Polymers Influence the Effect of Atorvastatin on Human Coronary Artery Cells
P2860
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P2860
Organic anion transporting polypeptide 2B1 is a high-affinity transporter for atorvastatin and is expressed in the human heart.
description
2006 nî lūn-bûn
@nan
2006 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Organic anion transporting pol ...... expressed in the human heart.
@ast
Organic anion transporting pol ...... expressed in the human heart.
@en
Organic anion transporting pol ...... expressed in the human heart.
@nl
type
label
Organic anion transporting pol ...... expressed in the human heart.
@ast
Organic anion transporting pol ...... expressed in the human heart.
@en
Organic anion transporting pol ...... expressed in the human heart.
@nl
prefLabel
Organic anion transporting pol ...... expressed in the human heart.
@ast
Organic anion transporting pol ...... expressed in the human heart.
@en
Organic anion transporting pol ...... expressed in the human heart.
@nl
P2093
P1476
Organic anion transporting pol ...... expressed in the human heart.
@en
P2093
Gabriele Jedlitschky
Heyo K Kroemer
Kathleen Köck
Katrin Draber
Konrad Meissner
Lothar Eckel
Markus Grube
Michael Böhm
Rolf Warzok
Silke Vogelgesang
P304
P356
10.1016/J.CLPT.2006.09.010
P407
P577
2006-12-01T00:00:00Z