Organic anion transporting polypeptide 2B1 is a high-affinity transporter for atorvastatin and is expressed in the human heart. - Wikidata - awgldk - TriplyDB

Organic anion transporting polypeptide 2B1 is a high-affinity transporter for atorvastatin and is expressed in the human heart.

Organic anion transporting polypeptide 2B1 is a high-affinity transporter for atorvastatin and is expressed in the human heart.

http://www.wikidata.org/entity/Q34573428

about

Role of Organic Anion-Transporting Polypeptides (OATPs) in Cancer Therapy OATPs, OATs and OCTs: the organic anion and cation transporters of the SLCO and SLC22A gene superfamilies Rapid modulation of the organic anion transporting polypeptide 2B1 (OATP2B1, SLCO2B1) function by protein kinase C-mediated internalization.H+-coupled nutrient, micronutrient and drug transporters in the mammalian small intestine Xenobiotic, bile acid, and cholesterol transporters: function and regulation.Mechanism of polybrominated diphenyl ether uptake into the liver: PBDE congeners are substrates of human hepatic OATP transporters A systems biology approach to dynamic modeling and inter-subject variability of statin pharmacokinetics in human hepatocytes.Genetic variation in drug transporters in ethnic populations.The SLCO (former SLC21) superfamily of transporters.Impact of OATP transporters on pharmacokinetics.Pharmacogenetic Foundations of Therapeutic Efficacy and Adverse Events of Statins.Selective regulation of cardiac organic cation transporter novel type 2 (OCTN2) in dilated cardiomyopathy Organic anion transporting polypeptides in the hepatic uptake of PBDE congeners in mice The expression and function of organic anion transporting polypeptides in normal tissues and in cancer Substrate- and pH-specific antifolate transport mediated by organic anion-transporting polypeptide 2B1 (OATP2B1-SLCO2B1)Pharmacokinetic interaction study of sulphasalazine in healthy subjects and the impact of curcumin as an in vivo inhibitor of BCRP.Targeted drug delivery to treat pain and cerebral hypoxia Interaction of silymarin flavonolignans with organic anion-transporting polypeptides.Involvement of organic anion transporting polypeptides in the toxicity of hydrophilic pravastatin and lipophilic fluvastatin in rat skeletal myofibres.Transporter-mediated uptake into cellular compartments.Role of OATP transporters in the disposition of drugs.Absorption of montelukast is transporter mediated: a common variant of OATP2B1 is associated with reduced plasma concentrations and poor response.Effects of selected OATP and/or ABC transporter inhibitors on the brain and whole-body distribution of glyburide.siRNA capsulated brain-targeted nanoparticles specifically knock down OATP2B1 in mice: a mechanism for acute morphine tolerance suppression Impact of cholesterol on ABC and SLC transporters expression and function and its role in disposition variability to lipid-lowering drugs.Statin regulation of CYP3A4 and CYP3A5 expression.The role of transporters in the pharmacokinetics of orally administered drugs.Transporter pharmacogenetics and statin toxicity.Hepatic OATP and OCT uptake transporters: their role for drug-drug interactions and pharmacogenetic aspects.Efflux and uptake transporters as determinants of statin response.Pharmacogenetics of drug-induced liver injury.Transporters, Trojan horses and therapeutics: suitability of bile acid and peptide transporters for drug delivery.Transporter-mediated drug-drug interactions.Functional characterization of drug uptake and metabolism in the heart.Current understanding of hepatic and intestinal OATP-mediated drug-drug interactions.Intestinal transporters for endogenic and pharmaceutical organic anions: the challenges of deriving in-vitro kinetic parameters for the prediction of clinically relevant drug-drug interactions.Transporter-mediated drug-drug interactions with oral antidiabetic drugs.Putative roles of organic anion transporting polypeptides (OATPs) in cell survival and progression of human cancers.Tissue thyroid hormones and thyronamines.Biodegradable Polymers Influence the Effect of Atorvastatin on Human Coronary Artery Cells

P2860

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P2860

Organic anion transporting polypeptide 2B1 is a high-affinity transporter for atorvastatin and is expressed in the human heart.

http://www.wikidata.org/entity/Q34573428

description

2006 nî lūn-bûn

@nan

2006 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2006 թվականի դեկտեմբերին հրատարակված գիտական հոդված

@hy

2006年の論文

@ja

2006年論文

@yue

2006年論文

@zh-hant

2006年論文

@zh-hk

2006年論文

@zh-mo

2006年論文

@zh-tw

2006年论文

@wuu

name

Organic anion transporting pol ...... expressed in the human heart.

@ast

Organic anion transporting pol ...... expressed in the human heart.

@en

Organic anion transporting pol ...... expressed in the human heart.

@nl

type

label

Organic anion transporting pol ...... expressed in the human heart.

@ast

Organic anion transporting pol ...... expressed in the human heart.

@en

Organic anion transporting pol ...... expressed in the human heart.

@nl

prefLabel

Organic anion transporting pol ...... expressed in the human heart.

@ast

Organic anion transporting pol ...... expressed in the human heart.

@en

Organic anion transporting pol ...... expressed in the human heart.

@nl

P1433

Q34573428-6E088FBC-0912-4789-B3A2-6A81CC67AE99

P1476

Q34573428-FC063707-8EC8-4F75-AA07-25301EC7907F

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Q34573428-14C023ED-2CA4-4B12-AE0F-AD06028E8A3C

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Q34573428-28A67C86-8BE8-4EBB-8E96-B85ECF4CB288

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Q34573428-70F0064B-967C-4F92-999E-75C1F7F58F50

Q34573428-757A0ACC-1494-409A-A470-58BE87B16632

Q34573428-9A3F11AB-4ECB-43B4-99A7-9B52B7434697

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Q34573428-AFB38D06-AE8F-4DEE-9A4C-28C4038D2FF2

Q34573428-B192B22D-0864-434E-9CB9-642776073683

P304

Q34573428-128E3888-AB76-40A9-AB33-5D8C03106F7D

P31

Q34573428-AAE52597-65A2-4896-A8CA-FF412F820400

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Q34573428-3CC580E1-6C42-4B52-BBE7-561A5D2595E5

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Q34573428-33D0F73D-DD7A-4D23-8FB7-34925065F165

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Q34573428-D32A3535-5C29-4D24-9B8D-7C67C7349D4F

P478

Q34573428-29360BCB-3979-426B-A0F3-E6943CBD086C

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Q34573428-03FDE7B5-7C21-40B5-8610-23B6FBE4C790

P698

Q34573428-DB68E592-9257-495D-9A89-22671230F5F9

P356

J.CLPT.2006.09.010

P1433

Clinical Pharmacology & Therapeutics

P1476

Organic anion transporting pol ...... expressed in the human heart.

@en

P2093

Gabriele Jedlitschky

http://www.w3.org/2001/XMLSchema#string

Heyo K Kroemer

http://www.w3.org/2001/XMLSchema#string

Kathleen Köck

http://www.w3.org/2001/XMLSchema#string

Katrin Draber

http://www.w3.org/2001/XMLSchema#string

Konrad Meissner

http://www.w3.org/2001/XMLSchema#string

Lothar Eckel

http://www.w3.org/2001/XMLSchema#string

Markus Grube

http://www.w3.org/2001/XMLSchema#string

Michael Böhm

http://www.w3.org/2001/XMLSchema#string

Rolf Warzok

http://www.w3.org/2001/XMLSchema#string

Silke Vogelgesang

http://www.w3.org/2001/XMLSchema#string

P304

607-620

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1016/J.CLPT.2006.09.010

http://www.w3.org/2001/XMLSchema#string

P407

P433

6

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P478

80

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P577

2006-12-01T00:00:00Z

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P698

17178262

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