PD-1 and LAG-3 inhibitory co-receptors act synergistically to prevent autoimmunity in mice
about
The immune microenvironment in Hodgkin lymphoma: T cells, B cells, and immune checkpointsLymphocyte-activation gene-3, an important immune checkpoint in cancerAdvances in immunotherapy for melanomaImmune checkpoint inhibitors: therapeutic advances in melanomaBeyond CTLA-4 and PD-1, the Generation Z of Negative Checkpoint RegulatorsDiacylglycerol Kinases (DGKs): Novel Targets for Improving T Cell Activity in CancerImmune checkpoint blockade: a common denominator approach to cancer therapyGene expression profiling of the response to interferon beta in Epstein-Barr-transformed and primary B cells of patients with multiple sclerosisCancer immunotherapy comes of ageAn evolving autoimmune microenvironment regulates the quality of effector T cell restimulation and functionBiochemical signaling of PD-1 on T cells and its functional implicationsCutting edge: accelerated autoimmune diabetes in the absence of LAG-3Immune inhibitory molecules LAG-3 and PD-1 synergistically regulate T-cell function to promote tumoral immune escapeTGF-β3-expressing CD4+CD25(-)LAG3+ regulatory T cells control humoral immune responsesCannabidiol, a non-psychoactive cannabinoid, leads to EGR2-dependent anergy in activated encephalitogenic T cells.Cell surface signaling molecules in the control of immune responses: a tide model.Cancer immunotherapy comes of ageImmune-checkpoint proteins VISTA and PD-1 nonredundantly regulate murine T-cell responses.Leukocyte-associated Ig-like receptor-1-deficient mice have an altered immune cell phenotype.Upregulation of Immune Checkpoint Molecules, PD-1 and LAG-3, on CD4+ and CD8+ T Cells after Gastric Cancer Surgery.Targeting the PD-1/B7-H1(PD-L1) pathway to activate anti-tumor immunity.Modulation of redox balance leaves murine diabetogenic TH1 T cells "LAG-3-ing" behind.Gene expression profiling in dermatitis herpetiformis skin lesions.Immunological biomarkers predict HIV-1 viral rebound after treatment interruptionBroad induction of immunoregulatory mechanisms after a short course of anti-IL-7Rα antibodies in NOD mice.Dual signaling by innate and adaptive immune receptors is required for TLR7-induced B-cell-mediated autoimmunity.LAG3 and PD1 co-inhibitory molecules collaborate to limit CD8+ T cell signaling and dampen antitumor immunity in a murine ovarian cancer modelVirotherapy, gene transfer and immunostimulatory monoclonal antibodies.Mechanistic basis of immunotherapies for type 1 diabetes mellitusCostimulatory and Coinhibitory Receptor Pathways in Infectious DiseaseGut environment-induced intraepithelial autoreactive CD4(+) T cells suppress central nervous system autoimmunity via LAG-3.Pathways and gene networks mediating the regulatory effects of cannabidiol, a nonpsychoactive cannabinoid, in autoimmune T cells.The heart of the matter: protection of the myocardium from T cellsSquamous cell carcinomas escape immune surveillance via inducing chronic activation and exhaustion of CD8+ T Cells co-expressing PD-1 and LAG-3 inhibitory receptors.Molecular pathways: coexpression of immune checkpoint molecules: signaling pathways and implications for cancer immunotherapyImpaired selection of IgA and intestinal dysbiosis associated with PD-1-deficiency.Apoptosis - an Ubiquitous T cell Immunomodulator.Molecular signatures of T-cell inhibition in HIV-1 infection.Control of inflammatory heart disease by CD4+ T cells.Novel antibodies targeting immune regulatory checkpoints for cancer therapy.
P2860
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P2860
PD-1 and LAG-3 inhibitory co-receptors act synergistically to prevent autoimmunity in mice
description
2011 nî lūn-bûn
@nan
2011 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
PD-1 and LAG-3 inhibitory co-r ...... o prevent autoimmunity in mice
@ast
PD-1 and LAG-3 inhibitory co-r ...... o prevent autoimmunity in mice
@en
PD-1 and LAG-3 inhibitory co-r ...... o prevent autoimmunity in mice
@nl
type
label
PD-1 and LAG-3 inhibitory co-r ...... o prevent autoimmunity in mice
@ast
PD-1 and LAG-3 inhibitory co-r ...... o prevent autoimmunity in mice
@en
PD-1 and LAG-3 inhibitory co-r ...... o prevent autoimmunity in mice
@nl
prefLabel
PD-1 and LAG-3 inhibitory co-r ...... o prevent autoimmunity in mice
@ast
PD-1 and LAG-3 inhibitory co-r ...... o prevent autoimmunity in mice
@en
PD-1 and LAG-3 inhibitory co-r ...... o prevent autoimmunity in mice
@nl
P2093
P2860
P50
P356
P1476
PD-1 and LAG-3 inhibitory co-r ...... o prevent autoimmunity in mice
@en
P2093
Kyoji Hioki
Sidonia Fagarasan
Taku Okazaki
Taku Yoshida
P2860
P304
P356
10.1084/JEM.20100466
P407
P577
2011-02-07T00:00:00Z