Transgenic mice with a reduced core body temperature have an increased life span.
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FeverGenome-environment interactions that modulate aging: powerful targets for drug discoverySingle-gene mutations and healthy ageing in mammalsThe neuroprotective properties of calorie restriction, the ketogenic diet, and ketone bodiesThe short-lived African turquoise killifish: an emerging experimental model for ageingThe role of mammalian sirtuins in the regulation of metabolism, aging, and longevitySchisandrin B as a hormetic agent for preventing age-related neurodegenerative diseasesRole of the hypothalamus in mediating protective effects of dietary restriction during agingNaturally occurring p16(Ink4a)-positive cells shorten healthy lifespanVoluntary Running Aids to Maintain High Body Temperature in Rats Bred for High Aerobic CapacityThe TRPM2 channel is a hypothalamic heat sensor that limits fever and can drive hypothermiaImpact of Longevity Interventions on a Validated Mouse Clinical Frailty IndexMice lacking brain-type creatine kinase activity show defective thermoregulation.Lack of interleukin-13 receptor α1 delays the loss of dopaminergic neurons during chronic stress.Ppargamma2 is a key driver of longevity in the mouse.Accurate temperature imaging based on intermolecular coherences in magnetic resonanceRegulation of the longevity response to temperature by thermosensory neurons in Caenorhabditis elegans.The effects of graded levels of calorie restriction: VIII. Impact of short term calorie and protein restriction on basal metabolic rate in the C57BL/6 mouseThe role of mitochondrial uncoupling proteins in lifespanHypothalamic and dietary control of temperature-mediated longevityThe effects of graded levels of calorie restriction: IX. Global metabolomic screen reveals modulation of carnitines, sphingolipids and bile acids in the liver of C57BL/6 mice.Mitohormesis: Promoting Health and Lifespan by Increased Levels of Reactive Oxygen Species (ROS).Thermoregulation in mice exhibits genetic variability early in senescenceEvidence for only two independent pathways for decreasing senescence in Caenorhabditis elegans.Age- and gender-specific changes of hypocretin immunopositive neurons in C57Bl/6 mice.Single cell transcriptomics of hypothalamic warm sensitive neurons that control core body temperature and fever response Signaling asymmetry and an extension of chemical neuroanatomy.Insulin-like growth factor 1-mediated hyperthermia involves anterior hypothalamic insulin receptors.The NAD World 2.0: the importance of the inter-tissue communication mediated by NAMPT/NAD+/SIRT1 in mammalian aging and longevity control.Altered thermoregulation via sensitization of A1 adenosine receptors in dietary-restricted rats.Caloric restriction and the aging process: a critiqueAfter a cold conditioning swim, UCP2-deficient mice are more able to defend against the cold than wild type mice.Mitochondrial uncoupling and lifespan.Further support to the uncoupling-to-survive theory: the genetic variation of human UCP genes is associated with longevity.Calorie restriction and prevention of age-associated chronic disease.Metabolic depression and increased reactive oxygen species production by isolated mitochondria at moderately lower temperatures.Running hot and cold: behavioral strategies, neural circuits, and the molecular machinery for thermotaxis in C. elegans and Drosophila.Being cool: how body temperature influences ageing and longevity.From the bush to the bench: the annual Nothobranchius fishes as a new model system in biology.Sex- and age-specific differences in core body temperature of C57Bl/6 mice.Mice as a mammalian model for research on the genetics of aging
P2860
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P2860
Transgenic mice with a reduced core body temperature have an increased life span.
description
2006 nî lūn-bûn
@nan
2006 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Transgenic mice with a reduced core body temperature have an increased life span.
@ast
Transgenic mice with a reduced core body temperature have an increased life span.
@en
Transgenic mice with a reduced core body temperature have an increased life span.
@nl
type
label
Transgenic mice with a reduced core body temperature have an increased life span.
@ast
Transgenic mice with a reduced core body temperature have an increased life span.
@en
Transgenic mice with a reduced core body temperature have an increased life span.
@nl
prefLabel
Transgenic mice with a reduced core body temperature have an increased life span.
@ast
Transgenic mice with a reduced core body temperature have an increased life span.
@en
Transgenic mice with a reduced core body temperature have an increased life span.
@nl
P2093
P50
P356
P1433
P1476
Transgenic mice with a reduced core body temperature have an increased life span.
@en
P2093
Eric P Zorrilla
Jacinta Lucero
Luis de Lecea
Raphaelle Winsky-Sommerer
Salvador Huitron-Resendiz
Sara Brownell
Steven Henriksen
Veronique Fabre
P304
P356
10.1126/SCIENCE.1132191
P407
P577
2006-11-01T00:00:00Z