Role for neutral sphingomyelinase-2 in tumor necrosis factor alpha-stimulated expression of vascular cell adhesion molecule-1 (VCAM) and intercellular adhesion molecule-1 (ICAM) in lung epithelial cells: p38 MAPK is an upstream regulator of nSMase2.
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Identification of Heat Shock Protein 60 as a Regulator of Neutral Sphingomyelinase 2 and Its Role in Dopamine UptakeNeutral sphingomyelinase 2 (nSMase2) is a phosphoprotein regulated by calcineurin (PP2B)Trafficking and Functions of Bioactive Sphingolipids: Lessons from Cells and Model MembranesRoles and regulation of neutral sphingomyelinase-2 in cellular and pathological processesNeutral sphingomyelinase 2 is palmitoylated on multiple cysteine residues. Role of palmitoylation in subcellular localizationEarly activation of nSMase2/ceramide pathway in astrocytes is involved in ischemia-associated neuronal damage via inflammation in rat hippocampiIdentification and characterization of murine mitochondria-associated neutral sphingomyelinase (MA-nSMase), the mammalian sphingomyelin phosphodiesterase 5Annexin II-dependent actin remodelling evoked by hydrogen peroxide requires the metalloproteinase/sphingolipid pathway.A novel mitochondrial sphingomyelinase in zebrafish cells.Stress-induced sphingolipid signaling: role of type-2 neutral sphingomyelinase in murine cell apoptosis and proliferation.The Polycomb group protein EED couples TNF receptor 1 to neutral sphingomyelinase.Expression and regulation of enzymes in the ceramide metabolic pathway in human retinal pigment epithelial cells and their relevance to retinal degeneration.Sphingomyelin metabolism at the plasma membrane: implications for bioactive sphingolipids.Anterograde and retrograde transport of neutral sphingomyelinase-2 between the Golgi and the plasma membrane.Lung injury and lung cancer caused by cigarette smoke-induced oxidative stress: Molecular mechanisms and therapeutic opportunities involving the ceramide-generating machinery and epidermal growth factor receptor.Regulation of CC ligand 5/RANTES by acid sphingomyelinase and acid ceramidase.Sphingolipid metabolites in inflammatory disease.Identification of novel anionic phospholipid binding domains in neutral sphingomyelinase 2 with selective binding preferenceProtein phosphatase 2A and neutral sphingomyelinase 2 regulate IRAK-1 protein ubiquitination and degradation in response to interleukin-1betaNF-kappaB, but not p38 MAP kinase, is required for TNF-alpha-induced expression of cell adhesion molecules in endothelial cells.Neutral sphingomyelinase 2 activity and protein stability are modulated by phosphorylation of five conserved serines.(R)-α-Lipoic acid treatment restores ceramide balance in aging rat cardiac mitochondria.Src regulates cigarette smoke-induced ceramide generation via neutral sphingomyelinase 2 in the airway epitheliumCharacterization and Functional Analysis of Extracellular Vesicles and Muscle-Abundant miRNAs (miR-1, miR-133a, and miR-206) in C2C12 Myocytes and mdx MiceHyperosmolarity-induced lipid droplet formation depends on ceramide production by neutral sphingomyelinase 2.Alterations in tumor necrosis factor signaling pathways are associated with cytotoxicity and resistance to taxanes: a study in isogenic resistant tumor cells.Regulation of neutral sphingomyelinase-2 (nSMase2) by tumor necrosis factor-alpha involves protein kinase C-delta in lung epithelial cellsConfluence induced threonine41/serine45 phospho-beta-catenin dephosphorylation via ceramide-mediated activation of PP1cgamma.Mutations in the neutral sphingomyelinase gene SMPD3 implicate the ceramide pathway in human leukemias.Ceramide limits phosphatidylinositol-3-kinase C2β-controlled cell motility in ovarian cancer: potential of ceramide as a metastasis-suppressor lipidFatty acid synthase causes drug resistance by inhibiting TNF-α and ceramide productionATRA transcriptionally induces nSMase2 through CBP/p300-mediated histone acetylation.Neutral sphingomyelinase 2 (nSMase2) is the primary neutral sphingomyelinase isoform activated by tumour necrosis factor-α in MCF-7 cells.Sphingosine kinase 1 regulates tumor necrosis factor-mediated RANTES induction through p38 mitogen-activated protein kinase but independently of nuclear factor κB activation.The role of iron in the pathogenesis of endometriosis.Mammalian neutral sphingomyelinases: regulation and roles in cell signaling responses.The neutral sphingomyelinase family: identifying biochemical connections.Sphingolipids and cancer: ceramide and sphingosine-1-phosphate in the regulation of cell death and drug resistance.Remodeling of sphingolipids by plasma membrane associated enzymes.The role of sphingolipids in respiratory disease.
P2860
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P2860
Role for neutral sphingomyelinase-2 in tumor necrosis factor alpha-stimulated expression of vascular cell adhesion molecule-1 (VCAM) and intercellular adhesion molecule-1 (ICAM) in lung epithelial cells: p38 MAPK is an upstream regulator of nSMase2.
description
2006 nî lūn-bûn
@nan
2006 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Role for neutral sphingomyelin ...... upstream regulator of nSMase2.
@ast
Role for neutral sphingomyelin ...... upstream regulator of nSMase2.
@en
Role for neutral sphingomyelin ...... cular cell adhesion molecule-1
@nl
type
label
Role for neutral sphingomyelin ...... upstream regulator of nSMase2.
@ast
Role for neutral sphingomyelin ...... upstream regulator of nSMase2.
@en
Role for neutral sphingomyelin ...... cular cell adhesion molecule-1
@nl
prefLabel
Role for neutral sphingomyelin ...... upstream regulator of nSMase2.
@ast
Role for neutral sphingomyelin ...... upstream regulator of nSMase2.
@en
Role for neutral sphingomyelin ...... cular cell adhesion molecule-1
@nl
P2860
P356
P1476
Role for neutral sphingomyelin ...... upstream regulator of nSMase2.
@en
P2093
Christopher J Clarke
Thach-Giao Truong
P2860
P304
P356
10.1074/JBC.M609216200
P407
P577
2006-11-03T00:00:00Z