Tumor-derived JAGGED1 promotes osteolytic bone metastasis of breast cancer by engaging notch signaling in bone cells - Wikidata - awgldk - TriplyDB

Tumor-derived JAGGED1 promotes osteolytic bone metastasis of breast cancer by engaging notch signaling in bone cells

Tumor-derived JAGGED1 promotes osteolytic bone metastasis of breast cancer by engaging notch signaling in bone cells

http://www.wikidata.org/entity/Q34580134

about

The notch ligand JAGGED1 as a target for anti-tumor therapy 14-3-3ζ turns TGF-β's function from tumor suppressor to metastasis promoter in breast cancer by contextual changes of Smad partners from p53 to Gli2 Dissecting Tumor-Stromal Interactions in Breast Cancer Bone Metastasis A Role for Notch Signalling in Breast Cancer and Endocrine Resistance Notch signaling in prostate cancer: refining a therapeutic opportunity Implications of the Hybrid Epithelial/Mesenchymal Phenotype in Metastasis Role of bone-anabolic agents in the treatment of breast cancer bone metastases Bone metastases: When and how lung cancer interacts with bone Notch: a key regulator of tumor angiogenesis and metastasis Targeting the Notch signaling pathway in cancer therapeutics Transcriptional control of cancer metastasis Notch signaling in prostate cancer: a moving target Targeting γ-secretase in breast cancer From fly wings to targeted cancer therapies: a centennial for notch signaling Notch regulation of bone development and remodeling and related skeletal disorders Targeting tumor-stromal interactions in bone metastasis Distinctive properties of metastasis-initiating cells Tumor cell dormancy NOTCH receptors in gastric and other gastrointestinal cancers: oncogenes or tumor suppressors?Metastatic colonization by circulating tumour cells What Is Breast in the Bone?The hematopoietic stem cell niche in homeostasis and disease TGFβ signalling in context Inflammation and skeletal metastasis SNAI1-mediated epithelial-mesenchymal transition confers chemoresistance and cellular plasticity by regulating genes involved in cell death and stem cell maintenance The novel gamma secretase inhibitor RO4929097 reduces the tumor initiating potential of melanoma Tumor metastasis: molecular insights and evolving paradigms The TGF-β Signaling Regulator PMEPA1 Suppresses Prostate Cancer Metastases to Bone The endochondral bone protein CHM1 sustains an undifferentiated, invasive phenotype, promoting lung metastasis in Ewing sarcoma.Aberrant Notch Signaling in the Bone Marrow Microenvironment of Acute Lymphoid Leukemia Suppresses Osteoblast-Mediated Support of Hematopoietic Niche Function.Angiocrine factors deployed by tumor vascular niche induce B cell lymphoma invasiveness and chemoresistance Jagged1 modulated tumor-associated macrophage differentiation predicts poor prognosis in patients with invasive micropapillary carcinoma of the breast.Bone-in-culture array as a platform to model early-stage bone metastases and discover anti-metastasis therapies Silencing of Jagged1 inhibits cell growth and invasion in colorectal cancer.Receptor of activated protein C promotes metastasis and correlates with clinical outcome in lung adenocarcinoma.Zoledronic acid effectiveness against breast cancer metastases - a role for estrogen in the microenvironment?Molecular mechanisms of bone metastasis and associated muscle weakness.MicroRNAs in the control of metastatic bone disease.Notch pathway inhibition controls myeloma bone disease in the murine MOPC315.BM model.EMT and MET: necessary or permissive for metastasis?

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Tumor-derived JAGGED1 promotes osteolytic bone metastasis of breast cancer by engaging notch signaling in bone cells

http://www.wikidata.org/entity/Q34580134

description

2011 nî lūn-bûn

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2011 թուականի Փետրուարին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի փետրվարին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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name

Tumor-derived JAGGED1 promotes ...... notch signaling in bone cells

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Tumor-derived JAGGED1 promotes ...... notch signaling in bone cells

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Tumor-derived JAGGED1 promotes ...... notch signaling in bone cells

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Tumor-derived JAGGED1 promotes ...... notch signaling in bone cells

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Tumor-derived JAGGED1 promotes ...... notch signaling in bone cells

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J.CCR.2010.12.022

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Tumor-derived JAGGED1 promotes ...... notch signaling in bone cells

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Christopher G Winter

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Nilay Sethi

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Xudong Dai

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Yibin Kang

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P2860

Jagged1-mediated Notch activation induces epithelial-to-mesenchymal transition through Slug-induced repression of E-cadherin.

Breast cancer bone metastasis mediated by the Smad tumor suppressor pathway

Latent bone metastasis in breast cancer tied to Src-dependent survival signals

Notch signaling: cell fate control and signal integration in development

High-level coexpression of JAG1 and NOTCH1 is observed in human breast cancer and is associated with poor overall survival

High-level JAG1 mRNA and protein predict poor outcome in breast cancer

The association of Notch2 and NF-kappaB accelerates RANKL-induced osteoclastogenesis

Genes that mediate breast cancer metastasis to lung

The canonical Notch signaling pathway: unfolding the activation mechanism.

A multigenic program mediating breast cancer metastasis to bone

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21295524

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