FKBP51 and Cyp40 are positive regulators of androgen-dependent prostate cancer cell growth and the targets of FK506 and cyclosporin A. - Wikidata - awgldk - TriplyDB

FKBP51 and Cyp40 are positive regulators of androgen-dependent prostate cancer cell growth and the targets of FK506 and cyclosporin A.

FKBP51 and Cyp40 are positive regulators of androgen-dependent prostate cancer cell growth and the targets of FK506 and cyclosporin A.

http://www.wikidata.org/entity/Q34580343

about

Cyclophilin 40 alters UVA-induced apoptosis and mitochondrial ROS generation in keratinocytes Stress-induced sex differences: adaptations mediated by the glucocorticoid receptor Steroid Receptor-Associated Immunophilins: A Gateway to Steroid Signalling FKBP51 and FKBP52 in signaling and disease Chaperoning steroidal physiology: lessons from mouse genetic models of Hsp90 and its cochaperones Structural characterization of the PPIase domain of FKBP51, a cochaperone of human Hsp90 A novel Hsp70 inhibitor prevents cell intoxication with the actin ADP-ribosylating Clostridium perfringens iota toxin Timcodar (VX-853) Is a Non-FKBP12 Binding Macrolide Derivative That Inhibits PPARγ and Suppresses Adipogenesis miR-99 family of MicroRNAs suppresses the expression of prostate-specific antigen and prostate cancer cell proliferation.Differential conformational dynamics in the closely homologous FK506-binding domains of FKBP51 and FKBP52.Glucocorticoid receptor β stimulates Akt1 growth pathway by attenuation of PTEN.Machine learning workflow to enhance predictions of Adverse Drug Reactions (ADRs) through drug-gene interactions: application to drugs for cutaneous diseases Targeting the regulation of androgen receptor signaling by the heat shock protein 90 cochaperone FKBP52 in prostate cancer cells.Differential impact of tetratricopeptide repeat proteins on the steroid hormone receptors NF-κB transcriptional activity is modulated by FK506-binding proteins FKBP51 and FKBP52: a role for peptidyl-prolyl isomerase activity.The heat shock protein-90 co-chaperone, Cyclophilin 40, promotes ALK-positive, anaplastic large cell lymphoma viability and its expression is regulated by the NPM-ALK oncoprotein.Cyclosporine A enhances Th2 bias at the maternal-fetal interface in early human pregnancy with aid of the interaction between maternal and fetal cells.Lemur Tyrosine Kinase 2, a novel target in prostate cancer therapy InterAKTions with FKBPs--mutational and pharmacological exploration.Versatile TPR domains accommodate different modes of target protein recognition and function FKBP51-a selective modulator of glucocorticoid and androgen sensitivity.Glucocorticoid sensitizers Bag1 and Ppid are regulated by adolescent stress in a sex-dependent manner ING3 promotes prostate cancer growth by activating the androgen receptor.FK506 binding protein 51 positively regulates melanoma stemness and metastatic potential.The emerging role of large immunophilin FK506 binding protein 51 in cancer Regulation of the glucocorticoid response to stress-related disorders by the Hsp90-binding immunophilin FKBP51.Hsp90-binding immunophilins as a potential new platform for drug treatment.Molecular cochaperones: tumor growth and cancer treatment.Biological relevance of Hsp90-binding immunophilins in cancer development and treatment.Quantitative proteomics suggests metabolic reprogramming during ETHE1 deficiency.FKBP51 regulates cell motility and invasion via RhoA signaling.Androgen Receptor and Androgen-Responsive Gene FKBP5 Are Independent Prognostic Indicators for Esophageal Adenocarcinoma.The isomerase PIN1 controls numerous cancer-driving pathways and is a unique drug target.The role of NFATc1 in prostate cancer progression: cyclosporine A and tacrolimus inhibit cell proliferation, migration, and invasion.Facile synthesis of a fluorescent cyclosporin a analogue to study cyclophilin 40 and cyclophilin 18 ligands.FKBP51 Null Mice Are Resistant to Diet-Induced Obesity and the PPARγ Agonist Rosiglitazone.Hsp90-binding immunophilin FKBP51 forms complexes with hTERT enhancing telomerase activity.A regulatory role for the co-chaperone FKBP51s in PD-L1 expression in glioma.Knockdown of the cochaperone SGTA results in the suppression of androgen and PI3K/Akt signaling and inhibition of prostate cancer cell proliferation.FK506-binding protein 51 is a possible novel tumoral marker.

P2860

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P2860

FKBP51 and Cyp40 are positive regulators of androgen-dependent prostate cancer cell growth and the targets of FK506 and cyclosporin A.

http://www.wikidata.org/entity/Q34580343

description

2009 nî lūn-bûn

@nan

2009 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2009 թվականի դեկտեմբերին հրատարակված գիտական հոդված

@hy

2009年の論文

@ja

2009年論文

@yue

2009年論文

@zh-hant

2009年論文

@zh-hk

2009年論文

@zh-mo

2009年論文

@zh-tw

2009年论文

@wuu

name

FKBP51 and Cyp40 are positive ...... ts of FK506 and cyclosporin A.

@ast

FKBP51 and Cyp40 are positive ...... ts of FK506 and cyclosporin A.

@en

FKBP51 and Cyp40 are positive ...... ts of FK506 and cyclosporin A.

@nl

type

label

FKBP51 and Cyp40 are positive ...... ts of FK506 and cyclosporin A.

@ast

FKBP51 and Cyp40 are positive ...... ts of FK506 and cyclosporin A.

@en

FKBP51 and Cyp40 are positive ...... ts of FK506 and cyclosporin A.

@nl

prefLabel

FKBP51 and Cyp40 are positive ...... ts of FK506 and cyclosporin A.

@ast

FKBP51 and Cyp40 are positive ...... ts of FK506 and cyclosporin A.

@en

FKBP51 and Cyp40 are positive ...... ts of FK506 and cyclosporin A.

@nl

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FKBP51 and Cyp40 are positive ...... ets of FK506 and cyclosporin A

@en

P2093

E R Sanchez

http://www.w3.org/2001/XMLSchema#string

L Shemshedini

http://www.w3.org/2001/XMLSchema#string

S Periyasamy

http://www.w3.org/2001/XMLSchema#string

W Shou

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P2860

A receptor for the immunosuppressant FK506 is a cis-trans peptidyl-prolyl isomerase

Structure and function of steroid receptor AF1 transactivation domains: induction of active conformations

The nuclear receptor superfamily: the second decade

Molecular cloning of human and rat complementary DNA encoding androgen receptors

The FK506-binding immunophilin FKBP51 is transcriptionally regulated by progestin and attenuates progestin responsiveness

Overexpression of FKBP51 in idiopathic myelofibrosis regulates the growth factor independence of megakaryocyte progenitors

Molecular determinants of resistance to antiandrogen therapy

Anti-androgens and the mutated androgen receptor of LNCaP cells: differential effects on binding affinity, heat-shock protein interaction, and transcription activation

Cochaperone immunophilin FKBP52 is critical to uterine receptivity for embryo implantation

Physiological role for the cochaperone FKBP52 in androgen receptor signaling

P2888

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1691-1701

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scholarly article

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10.1038/ONC.2009.458

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11

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29

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2009-12-21T00:00:00Z

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40731190

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1012650010

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20023700

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3040472

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