SUMOylation at K340 inhibits tau degradation through deregulating its phosphorylation and ubiquitination.
about
Sumoylation in Synaptic Function and DysfunctionCycloheximide Treatment Causes a ZVAD-Sensitive Protease-Dependent Cleavage of Human Tau in Drosophila CellsRoles of tau protein in health and disease.Tau interactome mapping based identification of Otub1 as Tau deubiquitinase involved in accumulation of pathological Tau forms in vitro and in vivo.Sequential posttranslational modifications regulate PKC degradation.Divergent signaling via SUMO modification: potential for CFTR modulation.Tau accumulation induces synaptic impairment and memory deficit by calcineurin-mediated inactivation of nuclear CaMKIV/CREB signalingAsperterpenes A and B, two unprecedented meroterpenoids from Aspergillus terreus with BACE1 inhibitory activities.Deep Phosphoproteomic Measurements Pinpointing Drug Induced Protective Mechanisms in Neuronal Cells.Battling Alzheimer's Disease: Targeting SUMOylation-Mediated Pathways.Intracellular and extracellular microtubule associated protein tau as a therapeutic target in Alzheimer disease and other tauopathies.Ubiquitin-dependent and independent roles of SUMO in proteostasis.Signaling pathways and posttranslational modifications of tau in Alzheimer's disease: the humanization of yeast cells.Role of microtubule-associated protein tau phosphorylation in Alzheimer's disease.Inhibition of CDK1 activity by sumoylation.Lysine-Directed Post-translational Modifications of Tau Protein in Alzheimer's Disease and Related Tauopathies.Modifications and Trafficking of APP in the Pathogenesis of Alzheimer's Disease.Protein SUMOylation modification and its associations with disease.Sex Differences in the Cognitive and Hippocampal Effects of Streptozotocin in an Animal Model of Sporadic AD.Tau Proteins and Tauopathies in Alzheimer's Disease.SUMOylation and ubiquitination reciprocally regulate α-synuclein degradation and pathological aggregation.Amyloidogenesis of Tau protein.PKC SUMOylation inhibits the binding of 14-3-3τ to GluK2.A single structurally conserved SUMOylation site in CRMP2 controls NaV1.7 function.Estrogen Modulates ubc9 Expression and Synaptic Redistribution in the Brain of APP/PS1 Mice and Cortical Neurons.Utilizing a Comprehensive Immunoprecipitation Enrichment System to Identify an Endogenous Post-translational Modification Profile for Target Proteins.Relevance of Phosphorylation and Truncation of Tau to the Etiopathogenesis of Alzheimer's Disease.TPPU protects tau from H2O2-induced hyperphosphorylation in HEK293/tau cells by regulating PI3K/AKT/GSK-3β pathway.Nature of Tau-Associated Neurodegeneration and the Molecular Mechanisms.SUMO1-conjugation is altered during normal aging but not by increased amyloid burden.Tau Spreading Mechanisms; Implications for Dysfunctional Tauopathies.BACE1 SUMOylation increases its stability and escalates the protease activity in Alzheimer's disease.Utilizing Optimized Tools to Investigate PTM Crosstalk: Identifying Potential PTM Crosstalk of Acetylated Mitochondrial Proteins.Phosphorylation of different tau sites during progression of Alzheimer's disease.Minimotifs dysfunction is pervasive in neurodegenerative disorders
P2860
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P2860
SUMOylation at K340 inhibits tau degradation through deregulating its phosphorylation and ubiquitination.
description
2014 nî lūn-bûn
@nan
2014 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
SUMOylation at K340 inhibits t ...... horylation and ubiquitination.
@ast
SUMOylation at K340 inhibits t ...... horylation and ubiquitination.
@en
SUMOylation at K340 inhibits t ...... horylation and ubiquitination.
@nl
type
label
SUMOylation at K340 inhibits t ...... horylation and ubiquitination.
@ast
SUMOylation at K340 inhibits t ...... horylation and ubiquitination.
@en
SUMOylation at K340 inhibits t ...... horylation and ubiquitination.
@nl
prefLabel
SUMOylation at K340 inhibits t ...... horylation and ubiquitination.
@ast
SUMOylation at K340 inhibits t ...... horylation and ubiquitination.
@en
SUMOylation at K340 inhibits t ...... horylation and ubiquitination.
@nl
P2093
P2860
P356
P1476
SUMOylation at K340 inhibits t ...... horylation and ubiquitination.
@en
P2093
Hong-Bin Luo
Jian-Zhi Wang
Keqiang Ye
Xiao-Chuan Wang
Xing-Hua Liu
P2860
P304
16586-16591
P356
10.1073/PNAS.1417548111
P407
P577
2014-11-05T00:00:00Z