Grb-2-associated binder 1 (Gab1) regulates postnatal ischemic and VEGF-induced angiogenesis through the protein kinase A-endothelial NOS pathway.
about
Grb2-associated binding (Gab) proteins in hematopoietic and immune cell biologyOrder and disorder in large multi-site docking proteins of the Gab family--implications for signalling complex formation and inhibitor design strategiesVEGFR2 induces c-Src signaling and vascular permeability in vivo via the adaptor protein TSAd.PKA turnover by the REGγ-proteasome modulates FoxO1 cellular activity and VEGF-induced angiogenesis.Acute mechanical stretch promotes eNOS activation in venous endothelial cells mainly via PKA and Akt pathways.Cytoplasmic tyrosine phosphatase Shp2 coordinates hepatic regulation of bile acid and FGF15/19 signaling to repress bile acid synthesis.Essential roles of Gab1 tyrosine phosphorylation in growth factor-mediated signaling and angiogenesisVEGF: Potential therapy for renal regenerationEffects of dietary L-arginine or N-carbamylglutamate supplementation during late gestation of sows on the miR-15b/16, miR-221/222, VEGFA and eNOS expression in umbilical vein.Reversal of renal dysfunction by targeted administration of VEGF into the stenotic kidney: a novel potential therapeutic approachEmerging role of PKA/eNOS pathway in therapeutic angiogenesis for ischaemic tissue diseasesPECAM1 regulates flow-mediated Gab1 tyrosine phosphorylation and signaling.Renoprotective effects of hepatocyte growth factor in the stenotic kidney.Angiogenic cytokines in renovascular disease: do they have potential for therapeutic use?Minicircle DNA-mediated endothelial nitric oxide synthase gene transfer enhances angiogenic responses of bone marrow-derived mesenchymal stem cells.A review on angiogenesis and its assaysHypertensive stretch regulates endothelial exocytosis of Weibel-Palade bodies through VEGF receptor 2 signaling pathways.CdGAP/ARHGAP31, a Cdc42/Rac1 GTPase regulator, is critical for vascular development and VEGF-mediated angiogenesis.Cardiac Gab1 deletion leads to dilated cardiomyopathy associated with mitochondrial damage and cardiomyocyte apoptosisGAB2 induces tumor angiogenesis in NRAS-driven melanoma.Plexin structures are coming: opportunities for multilevel investigations of semaphorin guidance receptors, their cell signaling mechanisms, and functions.Endothelial mechanosensors: the gatekeepers of vascular homeostasis and adaptation under mechanical stress.IFNγ-responsiveness of endothelial cells leads to efficient angiostasis in tumours involving down-regulation of Dll4.cAMP-dependent protein kinase A (PKA) regulates angiogenesis by modulating tip cell behavior in a Notch-independent manner.Scaffolding protein Gab1 regulates myeloid dendritic cell migration in allergic asthma.PI3K/AKT/PTEN Signaling as a Molecular Target in Leukemia Angiogenesis.Vascular importance of the miR-212/132 cluster.VEGF-A engages at least three tyrosine kinases to activate PI3K/Akt.Gab docking proteins in cardiovascular disease, cancer, and inflammation.Combined detection of Gab1 and Gab2 expression predicts clinical outcome of patients with glioma.Endothelial Gab1 deficiency aggravates splenomegaly in portal hypertension independent of angiogenesis.Cholinergic Grb2-Associated-Binding Protein 1 Regulates Cognitive Function.Shp2 promotes metastasis of prostate cancer by attenuating the PAR3/PAR6/aPKC polarity protein complex and enhancing epithelial-to-mesenchymal transition.Deficient angiogenesis in redox-dead Cys17Ser PKARIα knock-in mice.Extracellular calumenin suppresses ERK1/2 signaling and cell migration by protecting fibulin-1 from MMP-13-mediated proteolysis.Grb2-associated binder 1 is essential for cardioprotection against ischemia/reperfusion injury.Gαi1 and Gαi3mediate VEGF-induced VEGFR2 endocytosis, signaling and angiogenesis
P2860
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P2860
Grb-2-associated binder 1 (Gab1) regulates postnatal ischemic and VEGF-induced angiogenesis through the protein kinase A-endothelial NOS pathway.
description
2011 nî lūn-bûn
@nan
2011 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Grb-2-associated binder 1 (Gab ...... ase A-endothelial NOS pathway.
@ast
Grb-2-associated binder 1 (Gab ...... ase A-endothelial NOS pathway.
@en
Grb-2-associated binder 1
@nl
type
label
Grb-2-associated binder 1 (Gab ...... ase A-endothelial NOS pathway.
@ast
Grb-2-associated binder 1 (Gab ...... ase A-endothelial NOS pathway.
@en
Grb-2-associated binder 1
@nl
prefLabel
Grb-2-associated binder 1 (Gab ...... ase A-endothelial NOS pathway.
@ast
Grb-2-associated binder 1 (Gab ...... ase A-endothelial NOS pathway.
@en
Grb-2-associated binder 1
@nl
P2093
P2860
P356
P1476
Grb-2-associated binder 1 (Gab ...... ase A-endothelial NOS pathway.
@en
P2093
De-Sheng Zhu
Gen-Sheng Feng
Jincai Luo
Jingyan Han
Masabumi Shibuya
Rongli Zhang
Stefan Klein-Hessling
P2860
P304
P356
10.1073/PNAS.1009395108
P407
P577
2011-01-31T00:00:00Z