Hypoxia-inducible factor 2α (HIF-2α) heterozygous-null mice exhibit exaggerated carotid body sensitivity to hypoxia, breathing instability, and hypertension - Wikidata - awgldk - TriplyDB

Hypoxia-inducible factor 2α (HIF-2α) heterozygous-null mice exhibit exaggerated carotid body sensitivity to hypoxia, breathing instability, and hypertension

Hypoxia-inducible factor 2α (HIF-2α) heterozygous-null mice exhibit exaggerated carotid body sensitivity to hypoxia, breathing instability, and hypertension

http://www.wikidata.org/entity/Q34582873

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Hypoxia Inducible Factor Pathway and Physiological Adaptation: A Cell Survival Pathway?HIF hydroxylase pathways in cardiovascular physiology and medicine Peripheral chemoreception and arterial pressure responses to intermittent hypoxia Hypoxia-inducible factors in physiology and medicine K(+) channels in O(2) sensing and postnatal development of carotid body glomus cell response to hypoxia Hypoxia-inducible factors and hypertension: lessons from sleep apnea syndrome Interaction of Hydrogen Sulfide with Oxygen Sensing under Hypoxia Integrative analysis of DNA methylation and gene expression data identifies EPAS1 as a key regulator of COPD.Human high-altitude adaptation: forward genetics meets the HIF pathway.Sensory plasticity of the carotid body: role of reactive oxygen species and physiological significance.Epigenetic regulation of hypoxic sensing disrupts cardiorespiratory homeostasis.HIF1α is necessary for exercise-induced neuroprotection while HIF2α is needed for dopaminergic neuron survival in the substantia nigra pars compacta.Regulation of carotid body oxygen sensing by hypoxia-inducible factors Carotid chemoreceptor development in mice Neural regulation of hypoxia-inducible factors and redox state drives the pathogenesis of hypertension in a rodent model of sleep apnea Mutual antagonism between hypoxia-inducible factors 1α and 2α regulates oxygen sensing and cardio-respiratory homeostasis.Inhibition of hydrogen sulfide restores normal breathing stability and improves autonomic control during experimental heart failure.Calpain activation by ROS mediates human ether-a-go-go-related gene protein degradation by intermittent hypoxia.The role of hypoxia-inducible factors in oxygen sensing by the carotid body HIF isoforms in the skin differentially regulate systemic arterial pressure.Adaptive and maladaptive cardiorespiratory responses to continuous and intermittent hypoxia mediated by hypoxia-inducible factors 1 and 2.The von Hippel-Lindau Chuvash mutation in mice causes carotid-body hyperplasia and enhanced ventilatory sensitivity to hypoxia Human adaptation to the hypoxia of high altitude: the Tibetan paradigm from the pregenomic to the postgenomic era.Epinephrine: a short- and long-term regulator of stress and development of illness : a potential new role for epinephrine in stress.Gaseous messengers in oxygen sensing.Nitric oxide signaling in hypoxia.Carotid chemoreceptor "resetting" revisited.Sensing hypoxia: physiology, genetics and epigenetics.Selective carotid body ablation in experimental heart failure: a new therapeutic tool to improve cardiorespiratory control.Gene expression analyses reveal metabolic specifications in acute O2 -sensing chemoreceptor cells.Regulation of ventilatory sensitivity and carotid body proliferation in hypoxia by the PHD2/HIF-2 pathway Oxygen sensing by the carotid body: mechanisms and role in adaptation to hypoxia.Hypoxia and Its Acid-Base Consequences: From Mountains to Malignancy.Carotid body chemoreflex: a driver of autonomic abnormalities in sleep apnoea.Systems biology of oxygen homeostasis.Single cell transcriptome analysis of mouse carotid body glomus cells.Effects of intermittent hypoxia and hyperoxia on angiogenesis and lung development in newborn mice.Tackling chondrocyte hypertrophy with multifunctional nanoparticles.The effect of prenatal maternal infection on respiratory function in mouse offspring: evidence for enhanced chemosensitivity.Cardiovascular and respiratory responses to chronic intermittent hypoxia in adult female rats.

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P2860

Hypoxia-inducible factor 2α (HIF-2α) heterozygous-null mice exhibit exaggerated carotid body sensitivity to hypoxia, breathing instability, and hypertension

http://www.wikidata.org/entity/Q34582873

description

2011 nî lūn-bûn

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2011 թուականի Յունուարին հրատարակուած գիտական յօդուած

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2011 թվականի հունվարին հրատարակված գիտական հոդված

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2011年の論文

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Hypoxia-inducible factor 2α (H ...... instability, and hypertension

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Hypoxia-inducible factor 2α (H ...... instability, and hypertension

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Hypoxia-inducible factor 2α (H ...... instability, and hypertension

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Proceedings of the National Academy of Sciences of the United States of America

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Hypoxia-inducible factor 2α (H ...... instability, and hypertension

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Brian Kinsman

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Damodara R Vaddi

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Ganesh K Kumar

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Guoxiang Yuan

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Jayasri Nanduri

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Joseph A Garcia

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Nanduri R Prabhakar

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Ning Wang

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Shakil A Khan

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Ying-Jie Peng

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P2860

Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension

Endothelial PAS domain protein 1 (EPAS1), a transcription factor selectively expressed in endothelial cells

The hypoxia-responsive transcription factor EPAS1 is essential for catecholamine homeostasis and protection against heart failure during embryonic development

A novel bHLH-PAS factor with close sequence similarity to hypoxia-inducible factor 1alpha regulates the VEGF expression and is potentially involved in lung and vascular development

Cellular and developmental control of O2 homeostasis by hypoxia-inducible factor 1 alpha

Impaired physiological responses to chronic hypoxia in mice partially deficient for hypoxia-inducible factor 1alpha

Hypoxia-inducible factor 2alpha regulates expression of the mitochondrial aconitase chaperone protein frataxin

Cardiac hypertrophy in aryl hydrocarbon receptor null mice is correlated with elevated angiotensin II, endothelin-1, and mean arterial blood pressure

HIF-2alpha regulates murine hematopoietic development in an erythropoietin-dependent manner

Defective carotid body function and impaired ventilatory responses to chronic hypoxia in mice partially deficient for hypoxia-inducible factor 1 alpha

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108

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Gregg L. Semenza

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