Salinomycin sensitizes cancer cells to the effects of doxorubicin and etoposide treatment by increasing DNA damage and reducing p21 protein - Wikidata - awgldk - TriplyDB

Salinomycin sensitizes cancer cells to the effects of doxorubicin and etoposide treatment by increasing DNA damage and reducing p21 protein

Salinomycin sensitizes cancer cells to the effects of doxorubicin and etoposide treatment by increasing DNA damage and reducing p21 protein

http://www.wikidata.org/entity/Q34583585

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Salinomycin as a drug for targeting human cancer stem cells Salinomycin: a novel anti-cancer agent with known anti-coccidial activities Inhibitory Effects of Salinomycin on Cell Survival, Colony Growth, Migration, and Invasion of Human Non-Small Cell Lung Cancer A549 and LNM35: Involvement of NAG-1 Salinomycin activates AMP-activated protein kinase-dependent autophagy in cultured osteoblastoma cells: a negative regulator against cell apoptosis Salinomycin potentiates the cytotoxic effects of TRAIL on glioblastoma cell lines Inhibition of autophagic flux by salinomycin results in anti-cancer effect in hepatocellular carcinoma cells Salinomycin induced ROS results in abortive autophagy and leads to regulated necrosis in glioblastoma Synergistic induction of apoptosis by salinomycin and gefitinib through lysosomal and mitochondrial dependent pathway overcomes gefitinib resistance in colorectal cancer.Sensitization of cancer cells through reduction of total Akt and downregulation of salinomycin-induced pAkt, pGSk3β, pTSC2, and p4EBP1 by cotreatment with MK-2206.Cancer stem cells: involvement in pancreatic cancer pathogenesis and perspectives on cancer therapeutics.A late-stage intermediate in salinomycin biosynthesis is revealed by specific mutation in the biosynthetic gene cluster.Impact of Salinomycin on human cholangiocarcinoma: induction of apoptosis and impairment of tumor cell proliferation in vitro Salinomycin Suppresses PDGFRβ, MYC, and Notch Signaling in Human Medulloblastoma.Dose-dependent adverse effects of salinomycin on male reproductive organs and fertility in mice.Synthetic modification of salinomycin: selective O-acylation and biological evaluation.Sequential Salinomycin Treatment Results in Resistance Formation through Clonal Selection of Epithelial-Like Tumor Cells.Salinomycin induces calpain and cytochrome c-mediated neuronal cell death.Salinomycin inhibits prostate cancer growth and migration via induction of oxidative stress.Regulation of Hepatic Cholesteryl Ester Transfer Protein Expression and Reverse Cholesterol Transport by Inhibition of DNA Topoisomerase II Breast cancer stem cell selectivity of synthetic nanomolar-active salinomycin analogs Salinomycin exerts anti-angiogenic and anti-tumorigenic activities by inhibiting vascular endothelial growth factor receptor 2-mediated angiogenesis.Lower salinomycin concentration increases apoptotic detachment in high-density cancer cells.An in vitro study on the effects of the combination of salinomycin with cisplatin on human gastric cancer cells Stabilization of p21 (Cip1/WAF1) following Tip60-dependent acetylation is required for p21-mediated DNA damage response Inhibition of the autophagic flux by salinomycin in breast cancer stem-like/progenitor cells interferes with their maintenance Salinomycin induces cell death via inactivation of Stat3 and downregulation of Skp2.Salinomycin induces cell death with autophagy through activation of endoplasmic reticulum stress in human cancer cells.Combination of salinomycin and silver nanoparticles enhances apoptosis and autophagy in human ovarian cancer cells: an effective anticancer therapy.Low amount of salinomycin greatly increases Akt activation, but reduces activated p70S6K levels MiR-23a-mediated inhibition of topoisomerase 1 expression potentiates cell response to etoposide in human hepatocellular carcinoma.Hesperidin as a preventive resistance agent in MCF-7 breast cancer cells line resistance to doxorubicin.Low-dose salinomycin induces anti-leukemic responses in AML and MLL.Possibilities to increase the effectiveness of doxorubicin in cancer cells killing.Lysosomal Biology in Cancer.Effects of salinomycin and 17‑AAG on proliferation of human gastric cancer cells in vitro.Salinomycin exhibits anti-angiogenic activity against human glioma in vitro and in vivo by suppressing the VEGF-VEGFR2-AKT/FAK signaling axis.Induction of G1 Cell Cycle Arrest in Human Glioma Cells by Salinomycin Through Triggering ROS-Mediated DNA Damage In Vitro and In Vivo.Salinomycin radiosensitizes human nasopharyngeal carcinoma cell line CNE-2 to radiation.Synthesis, anticancer and antibacterial activity of salinomycin N-benzyl amides.Salinomycin increases chemosensitivity to the effects of doxorubicin in soft tissue sarcomas.

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Salinomycin sensitizes cancer cells to the effects of doxorubicin and etoposide treatment by increasing DNA damage and reducing p21 protein

http://www.wikidata.org/entity/Q34583585

description

2011 nî lūn-bûn

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2011 թուականի Փետրուարին հրատարակուած գիտական յօդուած

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2011 թվականի փետրվարին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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Salinomycin sensitizes cancer ...... amage and reducing p21 protein

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Salinomycin sensitizes cancer ...... amage and reducing p21 protein

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Salinomycin sensitizes cancer ...... amage and reducing p21 protein

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Salinomycin sensitizes cancer ...... amage and reducing p21 protein

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Salinomycin sensitizes cancer ...... amage and reducing p21 protein

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Salinomycin sensitizes cancer ...... amage and reducing p21 protein

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Salinomycin sensitizes cancer ...... amage and reducing p21 protein

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J.1476-5381.2010.01089.X

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British Journal of Pharmacology

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Salinomycin sensitizes cancer ...... amage and reducing p21 protein

@en

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Han Sung Kang

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Hyung Sik Kim

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Ju-Hwa Kim

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Minji Chae

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Sungpil Yoon

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Won Ki Kim

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You-Jin Kim

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P2860

Cell cycle, CDKs and cancer: a changing paradigm

Differential regulation of p53 and p21 by MKRN1 E3 ligase controls cell cycle arrest and apoptosis

A novel DNA-dependent protein kinase inhibitor, NU7026, potentiates the cytotoxicity of topoisomerase II poisons used in the treatment of leukemia

Identification of selective inhibitors of cancer stem cells by high-throughput screening

Increased SOCS6 stability with PMA requires its N-terminal region and the Erk pathway via Pkcdelta activation

Survivin: key regulator of mitosis and apoptosis and novel target for cancer therapeutics

Monitoring incorporation, transformation and subcellular distribution of N-l-leucyl-doxorubicin in uterine sarcoma cells using capillary electrophoretic techniques.

High throughput screening of a small molecule one-bead-one-compound combinatorial library to identify attenuators of p21 as chemotherapy sensitizers.

Salinomycin induces apoptosis and overcomes apoptosis resistance in human cancer cells.

Salinomycin overcomes ABC transporter-mediated multidrug and apoptosis resistance in human leukemia stem cell-like KG-1a cells.

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