Fast manipulation of cellular cAMP level by light in vivo.
about
Multiple-color optical activation, silencing, and desynchronization of neural activity, with single-spike temporal resolutionLight modulation of cellular cAMP by a small bacterial photoactivated adenylyl cyclase, bPAC, of the soil bacterium BeggiatoaHigh-efficiency channelrhodopsins for fast neuronal stimulation at low light levelsNatural and engineered photoactivated nucleotidyl cyclases for optogenetic applicationsGenetically-encoded tools for cAMP probing and modulation in living systemsThe genetically encoded tool set for investigating cAMP: more than the sum of its partsInvestigating neuronal function with optically controllable proteinsMolecular eyes: proteins that transform light into biological informationOptogenetic pharmacology for control of native neuronal signaling proteinsBimodal activation of different neuron classes with the spectrally red-shifted channelrhodopsin chimera C1V1 in Caenorhabditis elegansOptogenetic Control of Gene Expression in DrosophilaThe stimulatory Gα(s) protein is involved in olfactory signal transduction in DrosophilaNew tools for investigating astrocyte-to-neuron communication.Optogenetic approaches for dissecting neuromodulation and GPCR signaling in neural circuitsOptogenetic control of cells and circuitsMolecular and cellular approaches for diversifying and extending optogeneticsRegulation of nuclear PKA revealed by spatiotemporal manipulation of cyclic AMP.The Smell of Blue Light: A New Approach toward Understanding an Olfactory Neuronal Network.Improved molecular toolkit for cAMP studies in live cellsSpatial and temporal second messenger codes for growth cone turningOptogenetic manipulation of cGMP in cells and animals by the tightly light-regulated guanylyl-cyclase opsin CyclOpA plasma membrane microdomain compartmentalizes ephrin-generated cAMP signals to prune developing retinal axon arbors.Engineering of a red-light-activated human cAMP/cGMP-specific phosphodiesterase.Engineering adenylate cyclases regulated by near-infrared window lightHigh density and ligand affinity confer ultrasensitive signal detection by a guanylyl cyclase chemoreceptor.Reproducible and sustained regulation of Gαs signalling using a metazoan opsin as an optogenetic toolOld chromophores, new photoactivation paradigms, trendy applications: flavins in blue light-sensing photoreceptors.The microbial opsin family of optogenetic toolsSpecific expression of channelrhodopsin-2 in single neurons of Caenorhabditis elegans.Intermingled cAMP, cGMP and calcium spatiotemporal dynamics in developing neuronal circuits.Potency of transgenic effectors for neurogenetic manipulation in Drosophila larvae.Optimizing optogenetic constructs for control over signaling and cell behaviours.Autoregulatory and paracrine control of synaptic and behavioral plasticity by octopaminergic signalingNatural photoreceptors as a source of fluorescent proteins, biosensors, and optogenetic tools.Separate roles of PKA and EPAC in renal function unraveled by the optogenetic control of cAMP levels in vivoOptogenetic elevation of endogenous glucocorticoid level in larval zebrafish.A dynamic deep sleep stage in DrosophilaStructural insight into photoactivation of an adenylate cyclase from a photosynthetic cyanobacteriumNew photochemical tools for controlling neuronal activity.Genetically encoded molecular probes to visualize and perturb signaling dynamics in living biological systems
P2860
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P2860
Fast manipulation of cellular cAMP level by light in vivo.
description
2006 nî lūn-bûn
@nan
2006 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Fast manipulation of cellular cAMP level by light in vivo.
@ast
Fast manipulation of cellular cAMP level by light in vivo.
@en
Fast manipulation of cellular cAMP level by light in vivo.
@nl
type
label
Fast manipulation of cellular cAMP level by light in vivo.
@ast
Fast manipulation of cellular cAMP level by light in vivo.
@en
Fast manipulation of cellular cAMP level by light in vivo.
@nl
prefLabel
Fast manipulation of cellular cAMP level by light in vivo.
@ast
Fast manipulation of cellular cAMP level by light in vivo.
@en
Fast manipulation of cellular cAMP level by light in vivo.
@nl
P2093
P2860
P356
P1433
P1476
Fast manipulation of cellular cAMP level by light in vivo.
@en
P2093
Georg Nagel
Jens Looser
Martin Schwärzel
Masakatsu Watanabe
Peter Hegemann
Reinhard Seifert
Saskia Schröder-Lang
Suneel Kateriya
Timo Strünker
U Benjamin Kaupp
P2860
P2888
P356
10.1038/NMETH975
P577
2006-11-26T00:00:00Z
P5875
P6179
1009862919