Epoxyeicosatrienoic and dihydroxyeicosatrienoic acids dilate human coronary arterioles via BK(Ca) channels: implications for soluble epoxide hydrolase inhibition
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Soluble epoxide hydrolase as a therapeutic target for cardiovascular diseasesDiscovery of inhibitors of soluble epoxide hydrolase: a target with multiple potential therapeutic indicationsImpaired voltage gated potassium channel responses in a fetal lamb model of persistent pulmonary hypertension of the newbornCeramide changes the mediator of flow-induced vasodilation from nitric oxide to hydrogen peroxide in the human microcirculation.Cytochrome P450 epoxygenase pathway of polyunsaturated fatty acid metabolismRole of arachidonic acid lipoxygenase metabolites in the regulation of vascular toneCyclooxygenase- and cytochrome P450-derived eicosanoids in strokeAnti-inflammatory effects of epoxyeicosatrienoic acidsFunctional and pathological roles of the 12- and 15-lipoxygenasesSoluble epoxide hydrolase-dependent regulation of myogenic response and blood pressureGenetic variation in soluble epoxide hydrolase (EPHX2) is associated with forearm vasodilator responses in humansSoluble epoxide hydrolase gene deletion reduces survival after cardiac arrest and cardiopulmonary resuscitationInhibition of soluble epoxide hydrolase limits niacin-induced vasodilation in miceTargeting epoxides for organ damage in hypertensionEpoxyeicosatrienoic acids, hypertension, and kidney injuryRed blood cells (RBCs), epoxyeicosatrienoic acids (EETs) and adenosine triphosphate (ATP)Insulin resistance and endothelial dysfunction: Are epoxyeicosatrienoic acids the link?Inhibition of soluble epoxide hydrolase contributes to the anti-inflammatory effect of antimicrobial triclocarban in a murine modelSex- and isoform-specific mechanism of neuroprotection by transgenic expression of P450 epoxygenase in vascular endotheliumProtective actions of epoxyeicosatrienoic acid: dual targeting of cardiovascular PI3K and KATP channelsCytochrome P450 epoxygenases, soluble epoxide hydrolase, and the regulation of cardiovascular inflammationInhibition of soluble epoxide hydrolase preserves cardiomyocytes: role of STAT3 signalingPeripheral FAAH and soluble epoxide hydrolase inhibitors are synergistically antinociceptiveEpoxides and soluble epoxide hydrolase in cardiovascular physiologyOral treatment of rodents with soluble epoxide hydrolase inhibitor 1-(1-propanoylpiperidin-4-yl)-3-[4-(trifluoromethoxy)phenyl]urea (TPPU): Resulting drug levels and modulation of oxylipin patternVascular Endothelial Over-Expression of Human Soluble Epoxide Hydrolase (Tie2-sEH Tr) Attenuates Coronary Reactive Hyperemia in Mice: Role of Oxylipins and ω-HydroxylasesArachidonate Epoxygenase / Epoxide HydrolaseRole of caveolae in shear stress-mediated endothelium-dependent dilation in coronary arteries.11,12-Epoxyeicosatrienoic acid induces vasodilator response in the rat perfused mesenteric vasculature.Cytochrome P450 metabolites of arachidonic acid play a role in the enhanced cardiac dysfunction in diabetic rats following ischaemic reperfusion injury.Characterization of the Tissue Distribution of the Mouse Cyp2c Subfamily by Quantitative PCR Analysis.Epoxyeicosatrienoic Acids and 20-Hydroxyeicosatetraenoic Acid on Endothelial and Vascular Function.20-Hydroxyeicosatetraenoic acid induces apoptosis in neonatal rat cardiomyocytes through mitochondrial-dependent pathways.Epoxyeicosatrienoic acids are endogenous regulators of vasoactive neuropeptide release from trigeminal ganglion neuronsEndothelial expression of human cytochrome P450 epoxygenases lowers blood pressure and attenuates hypertension-induced renal injury in mice.Epoxyeicosatrienoic acid relaxing effects involve Ca2+-activated K+ channel activation and CPI-17 dephosphorylation in human bronchi.Role of arachidonic acid lipoxygenase metabolites in acetylcholine-induced relaxations of mouse arteries.Increases in plasma trans-EETs and blood pressure reduction in spontaneously hypertensive rats.Improvement of endothelium-dependent vasodilations by SKA-31 and SKA-20, activators of small- and intermediate-conductance Ca2+ -activated K+ -channels.Epoxyeicosatrienoic acids attenuating hypotonic-induced apoptosis of IMCD cells via γ-ENaC inhibition.
P2860
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P2860
Epoxyeicosatrienoic and dihydroxyeicosatrienoic acids dilate human coronary arterioles via BK(Ca) channels: implications for soluble epoxide hydrolase inhibition
description
2005 nî lūn-bûn
@nan
2005 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Epoxyeicosatrienoic and dihydr ...... man coronary arterioles via BK
@nl
Epoxyeicosatrienoic and dihydr ...... e epoxide hydrolase inhibition
@ast
Epoxyeicosatrienoic and dihydr ...... e epoxide hydrolase inhibition
@en
type
label
Epoxyeicosatrienoic and dihydr ...... man coronary arterioles via BK
@nl
Epoxyeicosatrienoic and dihydr ...... e epoxide hydrolase inhibition
@ast
Epoxyeicosatrienoic and dihydr ...... e epoxide hydrolase inhibition
@en
prefLabel
Epoxyeicosatrienoic and dihydr ...... man coronary arterioles via BK
@nl
Epoxyeicosatrienoic and dihydr ...... e epoxide hydrolase inhibition
@ast
Epoxyeicosatrienoic and dihydr ...... e epoxide hydrolase inhibition
@en
P2093
P2860
P1476
Epoxyeicosatrienoic and dihydr ...... e epoxide hydrolase inhibition
@en
P2093
Brandon T Larsen
Bruce D Hammock
David D Gutterman
Hiroto Miura
Ossama A Hatoum
William B Campbell
P2860
P304
P356
10.1152/AJPHEART.00927.2005
P577
2005-10-28T00:00:00Z