Role of GSK3 beta in behavioral abnormalities induced by serotonin deficiency. - Wikidata - awgldk - TriplyDB

Role of GSK3 beta in behavioral abnormalities induced by serotonin deficiency.

Role of GSK3 beta in behavioral abnormalities induced by serotonin deficiency.

http://www.wikidata.org/entity/Q34587440

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GSK-3 Inhibitors: Preclinical and Clinical Focus on CNS Genetic disruption of both tryptophan hydroxylase genes dramatically reduces serotonin and affects behavior in models sensitive to antidepressants.Interactome mapping of the phosphatidylinositol 3-kinase-mammalian target of rapamycin pathway identifies deformed epidermal autoregulatory factor-1 as a new glycogen synthase kinase-3 interactor Regulation of glycogen synthase kinase-3 during bipolar mania treatment Glycine site N-methyl-D-aspartate receptor antagonist 7-CTKA produces rapid antidepressant-like effects in male rats Growth retardation and altered autonomic control in mice lacking brain serotonin A new look at an old drug: neuroprotective effects and therapeutic potentials of lithium salts The 5-HT deficiency theory of depression: perspectives from a naturalistic 5-HT deficiency model, the tryptophan hydroxylase 2Arg439His knockin mouse Review of pharmacological treatment in mood disorders and future directions for drug development.Targeting brain serotonin synthesis: insights into neurodevelopmental disorders with long-term outcomes related to negative emotionality, aggression and antisocial behaviour Regulation of inflammation and T cells by glycogen synthase kinase-3: links to mood disorders Individual Differences in Behavioural Despair Predict Brain GSK-3beta Expression in Mice: The Power of a Modified Swim Test.Molecular genetics of mouse serotonin neurons across the lifespan.A role for Akt and glycogen synthase kinase-3 as integrators of dopamine and serotonin neurotransmission in mental health Stimulation of 5-HT2C receptors improves cognitive deficits induced by human tryptophan hydroxylase 2 loss of function mutation Haploinsufficiency for Pten and Serotonin transporter cooperatively influences brain size and social behavior.New therapeutic targets for mood disorders Serotonin deficiency alters susceptibility to the long-term consequences of adverse early life experience.Monoamine-sensitive developmental periods impacting adult emotional and cognitive behaviors.Genetic and pharmacological evidence for schizophrenia-related Disc1 interaction with GSK-3.Defective craniofacial development and brain function in a mouse model for depletion of intracellular inositol synthesis.Convergent effects of mouse Pet-1 deletion and human PET-1 variation on amygdala fear and threat processing Neurodevelopment in schizophrenia: the role of the wnt pathways.Behavioral and pharmacogenetics of aggressive behavior.GSK-3: Functional Insights from Cell Biology and Animal Models.Glycogen synthase kinase-3 in the etiology and treatment of mood disorders.Is glycogen synthase kinase-3 a central modulator in mood regulation?Modeling the positive symptoms of schizophrenia in genetically modified mice: pharmacology and methodology aspects The serotonergic system: its role in pathogenesis and early developmental treatment of autism.Abnormalities in brain structure and behavior in GSK-3alpha mutant mice RGS inhibition at G(alpha)i2 selectively potentiates 5-HT1A-mediated antidepressant effects.Deficiency in the inhibitory serine-phosphorylation of glycogen synthase kinase-3 increases sensitivity to mood disturbances.Genetic depletion of brain 5HT reveals a common molecular pathway mediating compulsivity and impulsivity A functional Tph2 C1473G polymorphism causes an anxiety phenotype via compensatory changes in the serotonergic system.Selective deletion of forebrain glycogen synthase kinase 3β reveals a central role in serotonin-sensitive anxiety and social behaviour Deficient serotonin neurotransmission and depression-like serotonin biomarker alterations in tryptophan hydroxylase 2 (Tph2) loss-of-function mice.Sex differences in response to chronic mild stress and congenital serotonin deficiency Genetic mapping of escalated aggression in wild-derived mouse strain MSM/Ms: association with serotonin-related genes.Regulating prefrontal cortex activation: an emerging role for the 5-HT₂A serotonin receptor in the modulation of emotion-based actions?Biological rhythms, higher brain function, and behavior: Gaps, opportunities, and challenges.

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P2860

Role of GSK3 beta in behavioral abnormalities induced by serotonin deficiency.

http://www.wikidata.org/entity/Q34587440

description

2008 nî lūn-bûn

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2008 թուականի Յունուարին հրատարակուած գիտական յօդուած

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2008 թվականի հունվարին հրատարակված գիտական հոդված

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2008年の論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年论文

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name

Role of GSK3 beta in behavioral abnormalities induced by serotonin deficiency.

@ast

Role of GSK3 beta in behavioral abnormalities induced by serotonin deficiency.

@en

Role of GSK3 beta in behavioral abnormalities induced by serotonin deficiency.

@nl

type

label

Role of GSK3 beta in behavioral abnormalities induced by serotonin deficiency.

@ast

Role of GSK3 beta in behavioral abnormalities induced by serotonin deficiency.

@en

Role of GSK3 beta in behavioral abnormalities induced by serotonin deficiency.

@nl

prefLabel

Role of GSK3 beta in behavioral abnormalities induced by serotonin deficiency.

@ast

Role of GSK3 beta in behavioral abnormalities induced by serotonin deficiency.

@en

Role of GSK3 beta in behavioral abnormalities induced by serotonin deficiency.

@nl

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PNAS.0711496105

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Proceedings of the National Academy of Sciences of the United States of America

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Role of GSK3 beta in behavioral abnormalities induced by serotonin deficiency.

@en

P2093

Marc G Caron

http://www.w3.org/2001/XMLSchema#string

Michael J Cools

http://www.w3.org/2001/XMLSchema#string

Ramona M Rodriguiz

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Tatyana D Sotnikova

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William C Wetsel

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Xiaodong Zhang

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P2860

A molecular mechanism for the effect of lithium on development

Requirement for glycogen synthase kinase-3beta in cell survival and NF-kappaB activation

A review of central 5-HT receptors and their function

Dopaminergic supersensitivity in G protein-coupled receptor kinase 6-deficient mice

New approaches to antidepressant drug discovery: beyond monoamines

Association of anxiety-related traits with a polymorphism in the serotonin transporter gene regulatory region

Synthesis of serotonin by a second tryptophan hydroxylase isoform

Role of serotonergic and noradrenergic systems in the pathophysiology of depression and anxiety disorders.

Mouse models of serotonin receptor function: toward a genetic dissection of serotonin systems.

Preliminary report of a simple animal behavior model for the anxiolytic effects of benzodiazepines.

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1333-1338

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10.1073/PNAS.0711496105

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105

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Jean-Martin Beaulieu

Raul Gainetdinov

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2008-01-22T00:00:00Z

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5639851

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18212115

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2234138

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