Pancreatic cell plasticity and cancer initiation induced by oncogenic Kras is completely dependent on wild-type PI 3-kinase p110α - Wikidata - awgldk - TriplyDB

Pancreatic cell plasticity and cancer initiation induced by oncogenic Kras is completely dependent on wild-type PI 3-kinase p110α

Pancreatic cell plasticity and cancer initiation induced by oncogenic Kras is completely dependent on wild-type PI 3-kinase p110α

http://www.wikidata.org/entity/Q34590266

about

Genetics and biology of pancreatic ductal adenocarcinoma Therapeutic potential of targeting acinar cell reprogramming in pancreatic cancer The acinar differentiation determinant PTF1A inhibits initiation of pancreatic ductal adenocarcinoma RAS signaling and anti-RAS therapy: lessons learned from genetically engineered mouse models, human cancer cells, and patient-related studies.MEK inhibitor GSK1120212-mediated radiosensitization of pancreatic cancer cells involves inhibition of DNA double-strand break repair pathways.SOX2 functions as a molecular rheostat to control the growth, tumorigenicity and drug responses of pancreatic ductal adenocarcinoma cells Addiction to Coupling of the Warburg Effect with Glutamine Catabolism in Cancer Cells.Acinar cell plasticity and development of pancreatic ductal adenocarcinoma.Systematic Review and Case Series Report of Acinar Cell Carcinoma of the Pancreas.Oncogenic KRAS Regulates Tumor Cell Signaling via Stromal Reciprocation.Insulin Receptor and GPCR Crosstalk Stimulates YAP via PI3K and PKD in Pancreatic Cancer Cells.Targeting Pancreatic Cancer Cell Plasticity: The Latest in Therapeutics.MTOR inhibitor-based combination therapies for pancreatic cancer.Mutant p53R270H drives altered metabolism and increased invasion in pancreatic ductal adenocarcinoma.Heterogeneity of Phosphatidylinositol-3-Kinase (PI3K)/AKT/Mammalian Target of Rapamycin Activation in Cancer: Is PI3K Isoform Specificity Important?Signal-Targeted Therapies and Resistance Mechanisms in Pancreatic Cancer: Future Developments Reside in Proteomics.Phosphoinositide 3-Kinase Signaling Pathway in Pancreatic Ductal Adenocarcinoma Progression, Pathogenesis, and Therapeutics.Effect of combined inhibition of p110 alpha PI3K isoform and STAT3 pathway in ovarian cancer platinum-based resistance.Stabilization of HIF-2α impacts pancreas growth

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P2860

Pancreatic cell plasticity and cancer initiation induced by oncogenic Kras is completely dependent on wild-type PI 3-kinase p110α

http://www.wikidata.org/entity/Q34590266

description

2014 nî lūn-bûn

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2014 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2014 թվականի դեկտեմբերին հրատարակված գիտական հոդված

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2014年の論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年论文

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Pancreatic cell plasticity and ...... on wild-type PI 3-kinase p110α

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Pancreatic cell plasticity and ...... on wild-type PI 3-kinase p110α

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Pancreatic cell plasticity and ...... on wild-type PI 3-kinase p110α

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Pancreatic cell plasticity and ...... on wild-type PI 3-kinase p110α

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Pancreatic cell plasticity and ...... on wild-type PI 3-kinase p110α

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Pancreatic cell plasticity and ...... on wild-type PI 3-kinase p110α

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Genes & Development

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Pancreatic cell plasticity and ...... on wild-type PI 3-kinase p110α

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Bart Vanhaesebroeck

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Bettina Couderc

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Corinne Bousquet

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Dieter Saur

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Hubert Lulka

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Laetitia Planque

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Marlène Dufresne

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Nina Schönhuber

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Stéphane Pyronnet

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Stéphanie Cassant-Sourdy

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P2860

Binding of ras to phosphoinositide 3-kinase p110alpha is required for ras-driven tumorigenesis in mice

Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes

Core signaling pathways in human pancreatic cancers revealed by global genomic analyses

Role of phosphoinositide 3-OH kinase in cell transformation and control of the actin cytoskeleton by Ras

EGF receptor is required for KRAS-induced pancreatic tumorigenesis

Mammalian Rho GTPases: new insights into their functions from in vivo studies

Pancreatic cancer

Trp53R172H and KrasG12D cooperate to promote chromosomal instability and widely metastatic pancreatic ductal adenocarcinoma in mice

The emerging mechanisms of isoform-specific PI3K signalling

Preinvasive and invasive ductal pancreatic cancer and its early detection in the mouse

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2621-2635

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scholarly article

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10.1101/GAD.249409.114

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23

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28

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Julie Guillermet-Guibert

Barbara Garmy-Susini

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2014-12-01T00:00:00Z

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269171408

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25452273

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4248293

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