Analysis of tumour- and stroma-supplied proteolytic networks reveals a brain-metastasis-promoting role for cathepsin S - Wikidata - awgldk - TriplyDB

Analysis of tumour- and stroma-supplied proteolytic networks reveals a brain-metastasis-promoting role for cathepsin S

Analysis of tumour- and stroma-supplied proteolytic networks reveals a brain-metastasis-promoting role for cathepsin S

http://www.wikidata.org/entity/Q34599128

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The Current and Future Treatment of Brain Metastases Molecular and Genetic Predictors of Breast-to-Brain Metastasis: Review and Case Presentation Cysteine cathepsins: their role in tumor progression and recent trends in the development of imaging probes Metastatic colonization by circulating tumour cells Breast Cancer Brain Metastases: Clonal Evolution in Clinical Context.Macrophage Ontogeny Underlies Differences in Tumor-Specific Education in Brain Malignancies.Exosomal microRNAs isolated from plasma of mesenteric veins linked to liver metastases in resected patients with colon cancer.Cell-to-cell communication in cancer: workshop report.Palmitoylation: a protein S-acylation with implications for breast cancer.Distinct functions of macrophage-derived and cancer cell-derived cathepsin Z combine to promote tumor malignancy via interactions with the extracellular matrix.Pericellular proteolysis in cancer Targeting metastasis-initiating cells through the fatty acid receptor CD36.Efficacy of Carboplatin Alone and in Combination with ABT888 in Intracranial Murine Models of BRCA-Mutated and BRCA-Wild-Type Triple-Negative Breast Cancer.βIII-Tubulin Regulates Breast Cancer Metastases to the Brain.Monocyte-derived macrophage assisted breast cancer cell invasion as a personalized, predictive metric to score metastatic risk.Cysteine cathepsin activity suppresses osteoclastogenesis of myeloid-derived suppressor cells in breast cancer Macrophage-secreted granulin supports pancreatic cancer metastasis by inducing liver fibrosis.Blood-brain barrier remodeling during brain metastasis formation.The metastasis suppressor RARRES3 as an endogenous inhibitor of the immunoproteasome expression in breast cancer cells Macrophages as Key Drivers of Cancer Progression and Metastasis.Nidogen-1 Degraded by Cathepsin S can be Quantified in Serum and is Associated with Non-Small Cell Lung Cancer.Inhibition of cathepsin S confers sensitivity to methyl protodioscin in oral cancer cells via activation of p38 MAPK/JNK signaling pathways.Proteolysis mediated by cysteine cathepsins and legumain-recent advances and cell biological challenges.Pathogenesis of Breast Cancer Metastasis to Brain: a Comprehensive Approach to the Signaling Network.CCL2 is transcriptionally controlled by the lysosomal protease cathepsin S in a CD74-dependent manner.Design of a highly selective quenched activity-based probe and its application in dual color imaging studies of cathepsin S activity localization.Integrated genomic and transcriptomic analysis of human brain metastases identifies alterations of potential clinical significance.Cathepsin S: therapeutic, diagnostic, and prognostic potential.The brain metastatic niche.Cathepsin-S degraded decorin are elevated in fibrotic lung disorders - development and biological validation of a new serum biomarker.Obesity alters the lung myeloid cell landscape to enhance breast cancer metastasis through IL5 and GM-CSF.Cell division cycle 7-kinase inhibitor PHA-767491 hydrochloride suppresses glioblastoma growth and invasiveness.Pre-metastatic niches: organ-specific homes for metastases.Procathepsin E is highly abundant but minimally active in pancreatic ductal adenocarcinoma tumors.Molecular insights into tumour metastasis: tracing the dominant events.Endothelial Cell Junctional Adhesion Molecules: Role and Regulation of Expression in Inflammation.Novel Approaches to Apoptosis-Inducing Therapies.Emerging Biological Principles of Metastasis.The Microenvironmental Landscape of Brain Tumors.A bioavailable cathepsin S nitrile inhibitor abrogates tumor development.

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Analysis of tumour- and stroma-supplied proteolytic networks reveals a brain-metastasis-promoting role for cathepsin S

http://www.wikidata.org/entity/Q34599128

description

2014 nî lūn-bûn

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2014 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

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2014 թվականի օգոստոսին հրատարակված գիտական հոդված

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2014年の論文

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2014年論文

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Analysis of tumour- and stroma ...... promoting role for cathepsin S

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Analysis of tumour- and stroma ...... promoting role for cathepsin S

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Analysis of tumour- and stroma ...... promoting role for cathepsin S

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Analysis of tumour- and stroma ...... promoting role for cathepsin S

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Analysis of tumour- and stroma ...... promoting role for cathepsin S

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Nature Cell Biology

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Benelita T Elie

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Christina S Leslie

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Daniela F Quail

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Edi Brogi

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Johanna A Joyce

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Leslie J Holsinger

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Lisa Sevenich

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Robert L Bowman

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Steven D Mason

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William C Hahn

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Bioconductor: open software development for computational biology and bioinformatics

Genes that mediate breast cancer metastasis to the brain

Astrocyte-endothelial interactions at the blood-brain barrier

Cathepsin S required for normal MHC class II peptide loading and germinal center development

affy--analysis of Affymetrix GeneChip data at the probe level

Genes that mediate breast cancer metastasis to lung

Metastasis: from dissemination to organ-specific colonization

A multigenic program mediating breast cancer metastasis to bone

The distribution of secondary growths in cancer of the breast. 1889

Microenvironmental regulation of tumor progression and metastasis

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10.1038/NCB3011

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9

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16

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Joan Massagué Solé

Priscilla K Brastianos

Franck Rapaport

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2014-08-03T00:00:00Z

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264430205

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25086747

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