Compartmentation prevents a lethal turbo-explosion of glycolysis in trypanosomes - Wikidata - awgldk - TriplyDB

Compartmentation prevents a lethal turbo-explosion of glycolysis in trypanosomes

Compartmentation prevents a lethal turbo-explosion of glycolysis in trypanosomes

http://www.wikidata.org/entity/Q34600277

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Molecular basis for the reverse reaction of African human trypanosomes glycerol kinase Characterization of the interaction between Trypanosoma brucei Pex5p and its receptor Pex14p A target-based high throughput screen yields Trypanosoma brucei hexokinase small molecule inhibitors with antiparasitic activity Diverse effects on mitochondrial and nuclear functions elicited by drugs and genetic knockdowns in bloodstream stage Trypanosoma brucei Channel-forming activities in the glycosomal fraction from the bloodstream form of Trypanosoma brucei Handling uncertainty in dynamic models: the pentose phosphate pathway in Trypanosoma brucei Dynamic modelling under uncertainty: the case of Trypanosoma brucei energy metabolism Rewiring and regulation of cross-compartmentalized metabolism in protists Trypanosomes contain two highly different isoforms of peroxin PEX13 involved in glycosome biogenesis.Localization of a Trypanosome Peroxin to the Endoplasmic Reticulum.Glycosome biogenesis in trypanosomes and the de novo dilemma.Autophagy in unicellular eukaryotes Evidence that intracellular stages of Leishmania major utilize amino sugars as a major carbon source.Contribution of pyruvate phosphate dikinase in the maintenance of the glycosomal ATP/ADP balance in the Trypanosoma brucei procyclic form.Leishmania amazonensis arginase compartmentalization in the glycosome is important for parasite infectivity.Lactate dehydrogenase C and energy metabolism in mouse sperm.Evidence for loss of a partial flagellar glycolytic pathway during trypanosomatid evolution Glycerol 3-phosphate alters Trypanosoma brucei hexokinase activity in response to environmental change Glycolysis in the african trypanosome: targeting enzymes and their subcellular compartments for therapeutic development ATG24 Represses Autophagy and Differentiation and Is Essential for Homeostasy of the Flagellar Pocket in Trypanosoma brucei.Identification, subcellular localization, biochemical properties, and high-resolution crystal structure of Trypanosoma brucei UDP-glucose pyrophosphorylase Systems biology from micro-organisms to human metabolic diseases: the role of detailed kinetic models.Glycosome turnover in Leishmania major is mediated by autophagy.Aquaglyceroporin-null trypanosomes display glycerol transport defects and respiratory-inhibitor sensitivity.The silicon trypanosome: a test case of iterative model extension in systems biology.Mitochondrial tRNA import--the challenge to understand has just begun Disclosing the essentiality of ribose-5-phosphate isomerase B in Trypanosomatids Extra-glycosomal localisation of Trypanosoma brucei hexokinase 2.Mitochondrial tRNA import in Trypanosoma brucei is independent of thiolation and the Rieske protein.Autophagy in trypanosomatids.Metabolomic systems biology of trypanosomes.Moonlighting enzymes in parasitic protozoa.The silicon trypanosome.Translocation of solutes and proteins across the glycosomal membrane of trypanosomes; possibilities and limitations for targeting with trypanocidal drugs.Understanding complexity in neurodegenerative diseases: in silico reconstruction of emergence.BD SIMULATIONS OF THE IONIC STRENGTH DEPENDENCE OF THE INTERACTIONS BETWEEN TRIOSE PHOSPHATE ISOMERASE AND F-ACTIN.Explicit consideration of topological and parameter uncertainty gives new insights into a well-established model of glycolysis.Inhibitors of PEX14 disrupt protein import into glycosomes and kill Trypanosoma parasites.Overproduction, purification, crystallization and preliminary X-ray diffraction analysis of Trypanosoma brucei gambiense glycerol kinase.What it takes to understand and cure a living system: computational systems biology and a systems biology-driven pharmacokinetics-pharmacodynamics platform.

P2860

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P2860

Compartmentation prevents a lethal turbo-explosion of glycolysis in trypanosomes

http://www.wikidata.org/entity/Q34600277

description

2008 nî lūn-bûn

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2008 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

@hyw

2008 թվականի նոյեմբերին հրատարակված գիտական հոդված

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2008年の論文

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2008年学术文章

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2008年学术文章

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2008年学术文章

@zh-hans

2008年学术文章

@zh-my

2008年学术文章

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2008年學術文章

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name

Compartmentation prevents a lethal turbo-explosion of glycolysis in trypanosomes

@ast

Compartmentation prevents a lethal turbo-explosion of glycolysis in trypanosomes

@en

Compartmentation prevents a lethal turbo-explosion of glycolysis in trypanosomes

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type

label

Compartmentation prevents a lethal turbo-explosion of glycolysis in trypanosomes

@ast

Compartmentation prevents a lethal turbo-explosion of glycolysis in trypanosomes

@en

Compartmentation prevents a lethal turbo-explosion of glycolysis in trypanosomes

@nl

prefLabel

Compartmentation prevents a lethal turbo-explosion of glycolysis in trypanosomes

@ast

Compartmentation prevents a lethal turbo-explosion of glycolysis in trypanosomes

@en

Compartmentation prevents a lethal turbo-explosion of glycolysis in trypanosomes

@nl

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PNAS.0806664105

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Proceedings of the National Academy of Sciences of the United States of America

P1476

Compartmentation prevents a lethal turbo-explosion of glycolysis in trypanosomes

@en

P2093

Arjen van Tuijl

http://www.w3.org/2001/XMLSchema#string

Paul A M Michels

http://www.w3.org/2001/XMLSchema#string

Peter Kessler

http://www.w3.org/2001/XMLSchema#string

Willem Reijnders

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P2860

Biogenesis and function of peroxisomes and glycosomes

The danger of metabolic pathways with turbo design

A tightly regulated inducible expression system for conditional gene knock-outs and dominant-negative genetics in Trypanosoma brucei

Subcloning, expression, purification, and characterization of Haemophilus influenzae glycerol kinase.

Glucose is toxic to glycosome-deficient trypanosomes.

Localization of nine glycolytic enzymes in a microbody-like organelle in Trypanosoma brucei: the glycosome.

Biogenesis of peroxisomes and glycosomes: trypanosomatid glycosome assembly is a promising new drug target.

The nature of systems biology.

Compartmentation of carbohydrate metabolism in trypanosomes.

Compartmentation protects trypanosomes from the dangerous design of glycolysis

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17718-17723

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scholarly article

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10.1073/PNAS.0806664105

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P433

46

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P478

105

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Hans Westerhoff

Jurgen R. Haanstra

Barbara M. Bakker

Marilyn Parsons

P577

2008-11-13T00:00:00Z

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P5875

23472735

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19008351

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P932

2584722

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