Compartmentation prevents a lethal turbo-explosion of glycolysis in trypanosomes
about
Molecular basis for the reverse reaction of African human trypanosomes glycerol kinaseCharacterization of the interaction between Trypanosoma brucei Pex5p and its receptor Pex14pA target-based high throughput screen yields Trypanosoma brucei hexokinase small molecule inhibitors with antiparasitic activityDiverse effects on mitochondrial and nuclear functions elicited by drugs and genetic knockdowns in bloodstream stage Trypanosoma bruceiChannel-forming activities in the glycosomal fraction from the bloodstream form of Trypanosoma bruceiHandling uncertainty in dynamic models: the pentose phosphate pathway in Trypanosoma bruceiDynamic modelling under uncertainty: the case of Trypanosoma brucei energy metabolismRewiring and regulation of cross-compartmentalized metabolism in protistsTrypanosomes contain two highly different isoforms of peroxin PEX13 involved in glycosome biogenesis.Localization of a Trypanosome Peroxin to the Endoplasmic Reticulum.Glycosome biogenesis in trypanosomes and the de novo dilemma.Autophagy in unicellular eukaryotesEvidence that intracellular stages of Leishmania major utilize amino sugars as a major carbon source.Contribution of pyruvate phosphate dikinase in the maintenance of the glycosomal ATP/ADP balance in the Trypanosoma brucei procyclic form.Leishmania amazonensis arginase compartmentalization in the glycosome is important for parasite infectivity.Lactate dehydrogenase C and energy metabolism in mouse sperm.Evidence for loss of a partial flagellar glycolytic pathway during trypanosomatid evolutionGlycerol 3-phosphate alters Trypanosoma brucei hexokinase activity in response to environmental changeGlycolysis in the african trypanosome: targeting enzymes and their subcellular compartments for therapeutic developmentATG24 Represses Autophagy and Differentiation and Is Essential for Homeostasy of the Flagellar Pocket in Trypanosoma brucei.Identification, subcellular localization, biochemical properties, and high-resolution crystal structure of Trypanosoma brucei UDP-glucose pyrophosphorylaseSystems biology from micro-organisms to human metabolic diseases: the role of detailed kinetic models.Glycosome turnover in Leishmania major is mediated by autophagy.Aquaglyceroporin-null trypanosomes display glycerol transport defects and respiratory-inhibitor sensitivity.The silicon trypanosome: a test case of iterative model extension in systems biology.Mitochondrial tRNA import--the challenge to understand has just begunDisclosing the essentiality of ribose-5-phosphate isomerase B in TrypanosomatidsExtra-glycosomal localisation of Trypanosoma brucei hexokinase 2.Mitochondrial tRNA import in Trypanosoma brucei is independent of thiolation and the Rieske protein.Autophagy in trypanosomatids.Metabolomic systems biology of trypanosomes.Moonlighting enzymes in parasitic protozoa.The silicon trypanosome.Translocation of solutes and proteins across the glycosomal membrane of trypanosomes; possibilities and limitations for targeting with trypanocidal drugs.Understanding complexity in neurodegenerative diseases: in silico reconstruction of emergence.BD SIMULATIONS OF THE IONIC STRENGTH DEPENDENCE OF THE INTERACTIONS BETWEEN TRIOSE PHOSPHATE ISOMERASE AND F-ACTIN.Explicit consideration of topological and parameter uncertainty gives new insights into a well-established model of glycolysis.Inhibitors of PEX14 disrupt protein import into glycosomes and kill Trypanosoma parasites.Overproduction, purification, crystallization and preliminary X-ray diffraction analysis of Trypanosoma brucei gambiense glycerol kinase.What it takes to understand and cure a living system: computational systems biology and a systems biology-driven pharmacokinetics-pharmacodynamics platform.
P2860
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P2860
Compartmentation prevents a lethal turbo-explosion of glycolysis in trypanosomes
description
2008 nî lūn-bûn
@nan
2008 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
name
Compartmentation prevents a lethal turbo-explosion of glycolysis in trypanosomes
@ast
Compartmentation prevents a lethal turbo-explosion of glycolysis in trypanosomes
@en
Compartmentation prevents a lethal turbo-explosion of glycolysis in trypanosomes
@nl
type
label
Compartmentation prevents a lethal turbo-explosion of glycolysis in trypanosomes
@ast
Compartmentation prevents a lethal turbo-explosion of glycolysis in trypanosomes
@en
Compartmentation prevents a lethal turbo-explosion of glycolysis in trypanosomes
@nl
prefLabel
Compartmentation prevents a lethal turbo-explosion of glycolysis in trypanosomes
@ast
Compartmentation prevents a lethal turbo-explosion of glycolysis in trypanosomes
@en
Compartmentation prevents a lethal turbo-explosion of glycolysis in trypanosomes
@nl
P2093
P2860
P50
P356
P1476
Compartmentation prevents a lethal turbo-explosion of glycolysis in trypanosomes
@en
P2093
Arjen van Tuijl
Paul A M Michels
Peter Kessler
Willem Reijnders
P2860
P304
17718-17723
P356
10.1073/PNAS.0806664105
P407
P577
2008-11-13T00:00:00Z