Expression of 5-lipoxygenase and leukotriene A4 hydrolase in human atherosclerotic lesions correlates with symptoms of plaque instability. - Wikidata - awgldk - TriplyDB

Expression of 5-lipoxygenase and leukotriene A4 hydrolase in human atherosclerotic lesions correlates with symptoms of plaque instability.

Expression of 5-lipoxygenase and leukotriene A4 hydrolase in human atherosclerotic lesions correlates with symptoms of plaque instability.

http://www.wikidata.org/entity/Q34601356

about

Phosphodiesterase 4D and 5-lipoxygenase activating protein genes and risk of ischemic stroke in Sardinians Discovery of Leukotriene A4 Hydrolase Inhibitors Using Metabolomics Biased Fragment Crystallography †Regulation of Nlrp3 inflammasome by dietary metabolites Mammalian lipoxygenases and their biological relevance Immunity, atherosclerosis and cardiovascular disease Oxidative risk for atherothrombotic cardiovascular disease.Blocking macrophage leukotriene b4 prevents endothelial injury and reverses pulmonary hypertension.Polyunsaturated fatty acids and cardiovascular disease: implications for nutrigenetics Significant Improvement Selected Mediators of Inflammation in Phenotypes of Women with PCOS after Reduction and Low GI Diet Pharmacological inhibition of BLT1 diminishes early abdominal aneurysm formation.Potential role of the lipoxygenase derived lipid mediators in atherosclerosis: leukotrienes, lipoxins and resolvins.Overview of recent drug discovery approaches for new generation leukotriene A4 hydrolase inhibitors.Cysteinyl leukotriene signaling aggravates myocardial hypoxia in experimental atherosclerotic heart disease Increased expression of leukotriene C4 synthase and predominant formation of cysteinyl-leukotrienes in human abdominal aortic aneurysm Nutrigenetic association of the 5-lipoxygenase gene with myocardial infarction Genetic contribution of the leukotriene pathway to coronary artery disease Leukotriene B4 receptor-1 mediates intermittent hypoxia-induced atherogenesis.Asthma predicts cardiovascular disease events: the multi-ethnic study of atherosclerosis Cell signalling by reactive lipid species: new concepts and molecular mechanisms.Disruption of the 5-lipoxygenase pathway attenuates atherogenesis consequent to COX-2 deletion in mice.Genetic and genomic insights into the molecular basis of atherosclerosis.Common Polymorphisms in the 5-Lipoxygenase Pathway and Risk of Incident Myocardial Infarction: A Danish Case-Cohort Study.Adipose tissue arachidonic acid content is associated with the expression of 5-lipoxygenase in atherosclerotic plaques.Leukotriene receptors in atherosclerosis.Atherosclerosis: evidence for impairment of resolution of vascular inflammation governed by specific lipid mediators Innate immunity, macrophage activation, and atherosclerosis.The potential link between atherosclerosis and the 5-lipoxygenase pathway: investigational agents with new implications for the cardiovascular field.Leukotriene B4 release from mast cells in IgE-mediated airway hyperresponsiveness and inflammation Coronary flow reserve from mouse to man--from mechanistic understanding to future interventions.Immune mechanisms in atherosclerosis, especially in diabetes type 2 An imbalance between specialized pro-resolving lipid mediators and pro-inflammatory leukotrienes promotes instability of atherosclerotic plaques.Inflammation and plaque vulnerability.Leukotriene B4 levels in human atherosclerotic plaques and abdominal aortic aneurysms.Treating inflammation in atherosclerotic cardiovascular disease: emerging therapies.The utility of collaborative biobanks for cardiovascular research.Inflammatory mediators involved in the progression of the metabolic syndrome.Eicosanoids and their drugs in cardiovascular diseases: focus on atherosclerosis and stroke.Regulatory effects of arachidonate 5-lipoxygenase on hepatic microsomal TG transfer protein activity and VLDL-triglyceride and apoB secretion in obese mice.Arterial inflammation in bronchial asthma.Boosting Inflammation Resolution in Atherosclerosis: The Next Frontier for Therapy.

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P2860

Expression of 5-lipoxygenase and leukotriene A4 hydrolase in human atherosclerotic lesions correlates with symptoms of plaque instability.

http://www.wikidata.org/entity/Q34601356

description

2006 nî lūn-bûn

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Proceedings of the National Academy of Sciences of the United States of America

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Anders Gabrielsen

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Anders Wetterholm

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Bengt Samuelsson

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Chi-Huey Wong

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Gabrielle Paulsson-Berne

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Göran K Hansson

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Hanna E Agardh

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Hong Qiu

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Jesper Swedenborg

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Jesper Z Haeggström

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P2860

Characterization of the human cysteinyl leukotriene CysLT1 receptor

A G-protein-coupled receptor for leukotriene B4 that mediates chemotaxis

A second leukotriene B(4) receptor, BLT2. A new therapeutic target in inflammation and immunological disorders

Expanding expression of the 5-lipoxygenase pathway within the arterial wall during human atherogenesis

Arachidonate 5-lipoxygenase promoter genotype, dietary arachidonic acid, and atherosclerosis

Role of leukotriene B4 receptors in the development of atherosclerosis: potential mechanisms

Inflammation, atherosclerosis, and coronary artery disease

Resolution of inflammation: the beginning programs the end

Characterization of the human cysteinyl leukotriene 2 receptor.

Leukotriene C4 synthase: a pivotal enzyme in cellular biosynthesis of the cysteinyl leukotrienes.

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atherosclerosis

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