Targeting the minor pocket of C5aR for the rational design of an oral allosteric inhibitor for inflammatory and neuropathic pain relief
about
Allosteric Modulation of Chemoattractant ReceptorsIdentification of novel natural compound inhibitors for human complement component 5a receptor by homology modeling and virtual screeningA Short Peptide That Mimics the Binding Domain of TGF-β1 Presents Potent Anti-Inflammatory ActivityMolecular and cellular mechanisms that initiate pain and itch.Netrin-1 Reduces Monocyte and Macrophage Chemotaxis towards the Complement Component C5a.The Complement System Component C5a Produces Thermal Hyperalgesia via Macrophage-to-Nociceptor Signaling That Requires NGF and TRPV1Structural complexes of the agonist, inverse agonist and antagonist bound C5a receptor: insights into pharmacology and signaling.The Complement System in Neuropathic and Postoperative Pain.Breaking barriers to novel analgesic drug development.Allosterism in human complement component 5a ((h)C5a): a damper of C5a receptor (C5aR) signaling.Complement C5a-C5aR interaction enhances MAPK signaling pathway activities to mediate renal injury in trichloroethylene sensitized BALB/c mice.The renaissance of complement therapeutics.CD177-mediated nanoparticle targeting of human and mouse neutrophils
P2860
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P2860
Targeting the minor pocket of C5aR for the rational design of an oral allosteric inhibitor for inflammatory and neuropathic pain relief
description
2014 nî lūn-bûn
@nan
2014 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Targeting the minor pocket of ...... ry and neuropathic pain relief
@ast
Targeting the minor pocket of ...... ry and neuropathic pain relief
@en
Targeting the minor pocket of ...... ry and neuropathic pain relief
@nl
type
label
Targeting the minor pocket of ...... ry and neuropathic pain relief
@ast
Targeting the minor pocket of ...... ry and neuropathic pain relief
@en
Targeting the minor pocket of ...... ry and neuropathic pain relief
@nl
prefLabel
Targeting the minor pocket of ...... ry and neuropathic pain relief
@ast
Targeting the minor pocket of ...... ry and neuropathic pain relief
@en
Targeting the minor pocket of ...... ry and neuropathic pain relief
@nl
P2093
P2860
P50
P356
P1476
Targeting the minor pocket of ...... ry and neuropathic pain relief
@en
P2093
Agostino Bruno
Alessio Moriconi
Alexandre H Lopes
Andrea Aramini
Andrea R Beccari
Cinzia Bizzarri
Emanuela Galliera
Gabriele Costantino
Gianluca Bianchini
Guilherme R Souza
P2860
P304
16937-16942
P356
10.1073/PNAS.1417365111
P407
P577
2014-11-10T00:00:00Z