Pharmacological basis for the role of curcumin in chronic diseases: an age-old spice with modern targets.
about
Towards a unifying, systems biology understanding of large-scale cellular death and destruction caused by poorly liganded iron: Parkinson's, Huntington's, Alzheimer's, prions, bactericides, chemical toxicology and others as examplesHerbal extracts and phytochemicals: plant secondary metabolites and the enhancement of human brain functionCurcumin and its derivatives: their application in neuropharmacology and neuroscience in the 21st centuryPotential effects of curcumin on peroxisome proliferator-activated receptor-γ in vitro and in vivoThe critical roles of miR-21 in anti-cancer effects of curcuminMitochondria: a new therapeutic target in chronic kidney diseaseTargeting colorectal cancer stem cells using curcumin and curcumin analogues: insights into the mechanism of the therapeutic efficacyHeterologous production of curcuminoidsCancer prevention with promising natural products: mechanisms of action and molecular targetsPharmacokinetic interactions of herbs with cytochrome p450 and p-glycoproteinPossible links between intestinal permeability and food processing: A potential therapeutic niche for glutamineCurcumin mediates both dilation and constriction of peripheral arterioles via adrenergic receptorsCurcumins-rich curry diet and pulmonary function in Asian older adultsCytotoxic effects of curcumin in human retinal pigment epithelial cellsCurcumin significantly enhances dual PI3K/Akt and mTOR inhibitor NVP-BEZ235-induced apoptosis in human renal carcinoma Caki cells through down-regulation of p53-dependent Bcl-2 expression and inhibition of Mcl-1 protein stabilityDifferential effects of methoxy group on the interaction of curcuminoids with two major ligand binding sites of human serum albuminCurcumin conjugated with PLGA potentiates sustainability, anti-proliferative activity and apoptosis in human colon carcinoma cellsThe anti-inflammatory activity of curcumin protects the genital mucosal epithelial barrier from disruption and blocks replication of HIV-1 and HSV-2Coaxial Electrospray of Curcumin-Loaded Microparticles for Sustained Drug ReleaseInhibition of IL-6 signaling pathway by curcumin in uterine decidual cellsCurcumin Mitigates the Intracellular Lipid Deposit Induced by Antipsychotics In VitroNovel STAT3 phosphorylation inhibitors exhibit potent growth-suppressive activity in pancreatic and breast cancer cellsDesign of curcumin-loaded PLGA nanoparticles formulation with enhanced cellular uptake, and increased bioactivity in vitro and superior bioavailability in vivo.Structure based comprehensive modelling, spatial fingerprints mapping and ADME screening of curcumin analogues as novel ALR2 inhibitors.Decrease of a specific biomarker of collagen degradation in osteoarthritis, Coll2-1, by treatment with highly bioavailable curcumin during an exploratory clinical trial.Design, synthesis, and biological evaluation of novel EF24 and EF31 analogs as potential IκB kinase β inhibitors for the treatment of pancreatic cancerCurcumin supplementation could improve diabetes-induced endothelial dysfunction associated with decreased vascular superoxide production and PKC inhibitionBinding of curcumin and its long chain derivatives to the activator binding domain of novel protein kinase C.Diet components can suppress inflammation and reduce cancer risk.Bisdemethylcurcumin and structurally related hispolon analogues of curcumin exhibit enhanced prooxidant, anti-proliferative and anti-inflammatory activities in vitro.Anti-inflammatory effects of resveratrol, curcumin and simvastatin in acute small intestinal inflammation.Curcumin blocks autophagy and activates apoptosis of malignant mesothelioma cell lines and increases the survival of mice intraperitoneally transplanted with a malignant mesothelioma cell line.Curcumin inhibits the AKT/NF-κB signaling via CpG demethylation of the promoter and restoration of NEP in the N2a cell line.Measurement of spices and seasonings in India: opportunities for cancer epidemiology and preventionCurcumin exerts its tumor suppressive function via inhibition of NEDD4 oncoprotein in glioma cancer cells.Curcumin reduces expression of Bcl-2, leading to apoptosis in daunorubicin-insensitive CD34+ acute myeloid leukemia cell lines and primary sorted CD34+ acute myeloid leukemia cells.Multi-center feasibility study evaluating recruitment, variability in risk factors and biomarkers for a diet and cancer cohort in India.Synthesis of 86 species of 1,5-diaryl-3-oxo-1,4-pentadienes analogs of curcumin can yield a good lead in vivo.Inhibition effect of curcumin on UVB-induced secretion of pro-inflammatory cytokines from corneal limbus epithelial cells.Curcumin induces EGFR degradation in lung adenocarcinoma and modulates p38 activation in intestine: the versatile adjuvant for gefitinib therapy.
P2860
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P2860
Pharmacological basis for the role of curcumin in chronic diseases: an age-old spice with modern targets.
description
2008 nî lūn-bûn
@nan
2008 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Pharmacological basis for the ...... old spice with modern targets.
@ast
Pharmacological basis for the ...... old spice with modern targets.
@en
Pharmacological basis for the ...... old spice with modern targets.
@nl
type
label
Pharmacological basis for the ...... old spice with modern targets.
@ast
Pharmacological basis for the ...... old spice with modern targets.
@en
Pharmacological basis for the ...... old spice with modern targets.
@nl
prefLabel
Pharmacological basis for the ...... old spice with modern targets.
@ast
Pharmacological basis for the ...... old spice with modern targets.
@en
Pharmacological basis for the ...... old spice with modern targets.
@nl
P1476
Pharmacological basis for the ...... old spice with modern targets.
@en
P2093
Bharat B Aggarwal
Bokyung Sung
P356
10.1016/J.TIPS.2008.11.002
P577
2008-12-26T00:00:00Z