Analysis of cellular and behavioral responses to imiquimod reveals a unique itch pathway in transient receptor potential vanilloid 1 (TRPV1)-expressing neurons.
about
Why we scratch an itch: the molecules, cells and circuits of itchNew insights into the mechanisms of itch: are pain and itch controlled by distinct mechanisms?Neural processing of itch.Itch mechanisms and circuits.Pirt, a TRPV1 modulator, is required for histamine-dependent and -independent itch.TLR4 enhances histamine-mediated pruritus by potentiating TRPV1 activity.Comprehensive RNA-Seq expression analysis of sensory ganglia with a focus on ion channels and GPCRs in Trigeminal gangliaA role for nociceptive, myelinated nerve fibers in itch sensation.Imiquimod enhances excitability of dorsal root ganglion neurons by inhibiting background (K(2P)) and voltage-gated (K(v)1.1 and K(v)1.2) potassium channels.Emerging role of Toll-like receptors in the control of pain and itch.Molecular and cellular mechanisms that initiate pain and itch.TLR3 deficiency impairs spinal cord synaptic transmission, central sensitization, and pruritus in mice.Regulation of Histone Acetylation by Autophagy in Parkinson DiseasePyruvate Dehydrogenase Kinase-mediated Glycolytic Metabolic Shift in the Dorsal Root Ganglion Drives Painful Diabetic Neuropathy.Trp channels and itch.Potentiation of the transient receptor potential vanilloid 1 channel contributes to pruritogenesis in a rat model of liver disease.Itch signaling in the nervous systemMouse models of acute, chemical itch and pain in humans.Itch pathophysiology may differ among ethnic groups.Investigational drugs for pruritus.Innate immune responses regulate morphogenesis and degeneration: roles of Toll-like receptors and Sarm1 in neurons.Targeting TRP ion channels for itch relief.The Gastrin-Releasing Peptide Receptor (GRPR) in the Spinal Cord as a Novel Pharmacological TargetTransplant restoration of spinal cord inhibitory controls ameliorates neuropathic itch.The TLR7 agonist imiquimod induces bronchodilation via a nonneuronal TLR7-independent mechanism: a possible role for quinoline in airway dilation.TLR7 signaling exacerbates CNS autoimmunity through downregulation of Foxp3+ Treg cells.The effect of imiquimod on taste bud calcium transients and transmitter secretion.PCR detects bands consistent with the expression of receptors associated with pruritus in canine dorsal root ganglia.Lysophosphatidic acid-induced itch is mediated by signalling of LPA5 receptor, phospholipase D and TRPA1/TRPV1.Frontiers in epidermal barrier homeostasis--an approach to mathematical modelling of epidermal calcium dynamics.The bronchodilatory capacity of imiquimod: the existence of two mechanisms.A zebrafish and mouse model for selective pruritus via direct activation of TRPA1.Skin neurogenic inflammation.
P2860
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P2860
Analysis of cellular and behavioral responses to imiquimod reveals a unique itch pathway in transient receptor potential vanilloid 1 (TRPV1)-expressing neurons.
description
2011 nî lūn-bûn
@nan
2011 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Analysis of cellular and behav ...... 1 (TRPV1)-expressing neurons.
@ast
Analysis of cellular and behav ...... 1 (TRPV1)-expressing neurons.
@en
Analysis of cellular and behav ...... receptor potential vanilloid 1
@nl
type
label
Analysis of cellular and behav ...... 1 (TRPV1)-expressing neurons.
@ast
Analysis of cellular and behav ...... 1 (TRPV1)-expressing neurons.
@en
Analysis of cellular and behav ...... receptor potential vanilloid 1
@nl
prefLabel
Analysis of cellular and behav ...... 1 (TRPV1)-expressing neurons.
@ast
Analysis of cellular and behav ...... 1 (TRPV1)-expressing neurons.
@en
Analysis of cellular and behav ...... receptor potential vanilloid 1
@nl
P2093
P2860
P356
P1476
Analysis of cellular and behav ...... 1 (TRPV1)-expressing neurons.
@en
P2093
C Justin Lee
Donghoon Kim
Estelle Wall
Goon Ho Park
Hyejung Min
Jaekwang Lee
Melvin I Simon
Sang-Kyou Han
Se-Jeong Kim
Sung Joong Lee
P2860
P304
P356
10.1073/PNAS.1019755108
P407
P577
2011-02-07T00:00:00Z