Small-molecule "BRCA1-mimetics" are antagonists of estrogen receptor-α
about
A new class of small molecule estrogen receptor-alpha antagonists that overcome anti-estrogen resistance.BRCA1-mimetic compound NSC35446.HCl inhibits IKKB expression by reducing estrogen receptor-α occupancy in the IKKB promoter and inhibits NF-κB activity in antiestrogen-resistant human breast cancer cells.ERα dimerization: a key factor for the weak estrogenic activity of an ERα modulator unable to compete with estradiol in binding assays.
P2860
Small-molecule "BRCA1-mimetics" are antagonists of estrogen receptor-α
description
2014 nî lūn-bûn
@nan
2014 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Small-molecule "BRCA1-mimetics" are antagonists of estrogen receptor-α
@ast
Small-molecule "BRCA1-mimetics" are antagonists of estrogen receptor-α
@en
Small-molecule "BRCA1-mimetics" are antagonists of estrogen receptor-α
@nl
type
label
Small-molecule "BRCA1-mimetics" are antagonists of estrogen receptor-α
@ast
Small-molecule "BRCA1-mimetics" are antagonists of estrogen receptor-α
@en
Small-molecule "BRCA1-mimetics" are antagonists of estrogen receptor-α
@nl
prefLabel
Small-molecule "BRCA1-mimetics" are antagonists of estrogen receptor-α
@ast
Small-molecule "BRCA1-mimetics" are antagonists of estrogen receptor-α
@en
Small-molecule "BRCA1-mimetics" are antagonists of estrogen receptor-α
@nl
P2093
P2860
P356
P1476
Small-molecule "BRCA1-mimetics" are antagonists of estrogen receptor-α
@en
P2093
Anju Preet
Eliot M Rosen
Eliseu De Oliveira
Erikah Englund
Milton L Brown
Scott Grindrod
Shyam Nathan
Yongxian Ma
York Tomita
P2860
P304
P356
10.1210/ME.2014-1146
P577
2014-12-01T00:00:00Z