Qualitative and quantitative differences in the pathways of extrathyroidal triiodothyronine generation between euthyroid and hypothyroid rats - Wikidata - awgldk - TriplyDB

Qualitative and quantitative differences in the pathways of extrathyroidal triiodothyronine generation between euthyroid and hypothyroid rats

Qualitative and quantitative differences in the pathways of extrathyroidal triiodothyronine generation between euthyroid and hypothyroid rats

http://www.wikidata.org/entity/Q34606826

about

Cloning of the mammalian type II iodothyronine deiodinase. A selenoprotein differentially expressed and regulated in human and rat brain and other tissues Abnormal motor phenotype at adult stages in mice lacking type 2 deiodinase Guidelines for the treatment of hypothyroidism: prepared by the american thyroid association task force on thyroid hormone replacement Cloning, expression, and functional characterization of the substrate binding subunit of rat type II iodothyronine 5'-deiodinase.Estimating Margin of Exposure to Thyroid Peroxidase Inhibitors Using High-Throughput in vitro Data, High-Throughput Exposure Modeling, and Physiologically Based Pharmacokinetic/Pharmacodynamic Modeling.Physiological and genetic analyses of inbred mouse strains with a type I iodothyronine 5' deiodinase deficiency.Variation in the biochemical response to l-thyroxine therapy and relationship with peripheral thyroid hormone conversion efficiency Alterations in 3,3'5'-triiodothyronine metabolism in response to propylthiouracil, dexamethasone, and thyroxine administration in man Characteristics of thyroxine 5'-deiodination in cultured human placental cells. Regulation by iodothyronines Potential of brown adipose tissue type II thyroxine 5'-deiodinase as a local and systemic source of triiodothyronine in rats Interrelationships among thyroxine, growth hormone, and the sympathetic nervous system in the regulation of 5'-iodothyronine deiodinase in rat brown adipose tissue.Production rates and turnover of triiodothyronine in rat-developing cerebral cortex and cerebellum. Responses to hypothyroidism Decreased serum triiodothyronine in starving rats is due primarily to diminished thyroidal secretion of thyroxine The central effects of thyroid hormones on appetite.The Effects of Thyroid Hormones on Gene Expression of Acyl-Coenzyme A Thioesterases in Adipose Tissue and Liver of Mice.Effect of Hypothyroidism and Hyperthyroidism on Tissue Thyroid Hormone Concentrations in Rat.Induction of type 2 iodothyronine deiodinase in astrocytes after transient focal cerebral ischemia in the rat.Metabolism of reverse triiodothyronine by isolated rat hepatocytes.Accumulation of plasma triiodothyronine sulfate in rats treated with propylthiouracil Direct assessment of brown adipose tissue as a site of systemic tri-iodothyronine production in the rat.Thyroid function and cold acclimation in the hamster, Mesocricetus auratus.5'-Deiodinase type 1 activity in liver and brain of the thyroxine-treated dystrophic hamster.Optimal response of key enzymes and uncoupling protein to cold in BAT depends on local T3 generation.Effect of increased carbohydrate utilization potential on cardiac isomyosin in thyroidectomized rats.Neurodevelopment and Thyroid Hormone Synthesis Inhibition in the Rat: Quantitative Understanding Within the Adverse Outcome Pathway Framework.Iodothyronine deiodination in the brain of diabetic rats: influence of thyroid status.

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Qualitative and quantitative differences in the pathways of extrathyroidal triiodothyronine generation between euthyroid and hypothyroid rats

http://www.wikidata.org/entity/Q34606826

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1984 nî lūn-bûn

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1984 թուականի Ապրիլին հրատարակուած գիտական յօդուած

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1984 թվականի ապրիլին հրատարակված գիտական հոդված

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1984年の論文

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1984年論文

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1984年論文

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Qualitative and quantitative d ...... euthyroid and hypothyroid rats

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Journal of Clinical Investigation

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Qualitative and quantitative d ...... euthyroid and hypothyroid rats

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F R Crantz

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J E Silva

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J L Leonard

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M B Gordon

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P R Larsen

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P2860

Effect of starvation, nutriment replacement, and hypothyroidism on in vitro hepatic T4 to T3 conversion in the rat.

The extrathyroidal conversion rate of thyroxine to triiodothyronine in normal man.

Determination of iodothyronine absorption and conversion of L-thyroxine (T 4 ) to L-triiodothyronine (T 3 ) using turnover rate techniques

Quantitation of extrathyroidal conversion of L-thyroxine to 3,5,3'-triiodo-L-thyronine in the rat

Evidence for two pathways of iodothyronine 5'-deiodination in rat pituitary that differ in kinetics, propylthiouracil sensitivity, and response to hypothyroidism.

Kinetic evidence suggesting two mechanisms for iodothyronine 5'-deiodination in rat cerebral cortex.

Evidence for two tissue-specific pathways for in vivo thyroxine 5'-deiodination in the rat.

Comparison of iodothyronine 5'-deiodinase and other thyroid-hormone-dependent enzyme activities in the cerebral cortex of hypothyroid neonatal rat. Evidence for adaptation to hypothyroidism

A study of extrathyroidal conversion of thyroxine (T4) to 3,3',5-triiodothyronine (T3) in vitro.

Pathways of metabolism of thyroid hormones.

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898-907

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10.1172/JCI111313

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6707210

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