Rearrangements of 2.5 kilobases of noncoding DNA from the Drosophila even-skipped locus define predictive rules of genomic cis-regulatory logic
about
Effects of Gene Dose, Chromatin, and Network Topology on Expression in Drosophila melanogasterWhat does it take to evolve an enhancer? A simulation-based study of factors influencing the emergence of combinatorial regulationThe appeasement of Doug: a synthetic approach to enhancer biology.Incorporating chromatin accessibility data into sequence-to-expression modelingNaturally occurring deletions of hunchback binding sites in the even-skipped stripe 3+7 enhancerA gene expression atlas of a bicoid-depleted Drosophila embryo reveals early canalization of cell fate.Shadow enhancers enable Hunchback bifunctionality in the Drosophila embryoQuantitative modeling of a gene's expression from its intergenic sequence.Reliable scaling of position weight matrices for binding strength comparisons between transcription factors.A Systematic Ensemble Approach to Thermodynamic Modeling of Gene Expression from Sequence Data.A Looping-Based Model for Quenching Repression.In silico evolution of the Drosophila gap gene regulatory sequence under elevated mutational pressurePredicting the impact of promoter variability on regulatory outputsParallel Simulated Annealing Using an Adaptive Resampling IntervalCellular resolution models for even skipped regulation in the entire Drosophila embryoDifferent modes of enhancer-specific regulation by Runt and Even-skipped during Drosophila segmentation.Ancestral resurrection of the Drosophila S2E enhancer reveals accessible evolutionary paths through compensatory change.Backward-stochastic-differential-equation approach to modeling of gene expression.Stochastic model for gene transcription on Drosophila melanogaster embryos.The analysis of novel distal Cebpa enhancers and silencers using a transcriptional model reveals the complex regulatory logic of hematopoietic lineage specification.A sequence level model of an intact locus predicts the location and function of nonadditive enhancers.Translating natural genetic variation to gene expression in a computational model of the Drosophila gap gene regulatory network.Natural variation of the expression pattern of the segmentation gene even-skipped in melanogasterQuantitative Measurement and Thermodynamic Modeling of Fused Enhancers Support a Two-Tiered Mechanism for Interpreting Regulatory DNA.Quantitatively predictable control of Drosophila transcriptional enhancers in vivo with engineered transcription factors.Synthetic enhancer design by in silico compensatory evolution reveals flexibility and constraint in cis-regulation.Hunchback is counter-repressed to regulate even-skipped stripe 2 expression in Drosophila embryos
P2860
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P2860
Rearrangements of 2.5 kilobases of noncoding DNA from the Drosophila even-skipped locus define predictive rules of genomic cis-regulatory logic
description
2013 nî lūn-bûn
@nan
2013 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
Rearrangements of 2.5 kilobase ...... f genomic cis-regulatory logic
@ast
Rearrangements of 2.5 kilobase ...... f genomic cis-regulatory logic
@en
Rearrangements of 2.5 kilobase ...... f genomic cis-regulatory logic
@nl
type
label
Rearrangements of 2.5 kilobase ...... f genomic cis-regulatory logic
@ast
Rearrangements of 2.5 kilobase ...... f genomic cis-regulatory logic
@en
Rearrangements of 2.5 kilobase ...... f genomic cis-regulatory logic
@nl
prefLabel
Rearrangements of 2.5 kilobase ...... f genomic cis-regulatory logic
@ast
Rearrangements of 2.5 kilobase ...... f genomic cis-regulatory logic
@en
Rearrangements of 2.5 kilobase ...... f genomic cis-regulatory logic
@nl
P2093
P2860
P1433
P1476
Rearrangements of 2.5 kilobase ...... f genomic cis-regulatory logic
@en
P2093
Ah-Ram Kim
Alexandre F Ramos
Carlos Martinez
David H Sharp
John Ionides
John Reinitz
Michael Z Ludwig
Nobuo Ogawa
P2860
P304
P356
10.1371/JOURNAL.PGEN.1003243
P577
2013-02-28T00:00:00Z