Mode of selection and experimental evolution of antifungal drug resistance in Saccharomyces cerevisiae
about
Chemical-genetic profile analysis in yeast suggests that a previously uncharacterized open reading frame, YBR261C, affects protein synthesisMembrane-active compounds activate the transcription factors Pdr1 and Pdr3 connecting pleiotropic drug resistance and membrane lipid homeostasis in saccharomyces cerevisiaeRapid experimental evolution of pesticide resistance in C. elegans entails no costs and affects the mating systemPKC signaling regulates drug resistance of the fungal pathogen Candida albicans via circuitry comprised of Mkc1, calcineurin, and Hsp90Discovery of a HapE mutation that causes azole resistance in Aspergillus fumigatus through whole genome sequencing and sexual crossingGenetic and genomic architecture of the evolution of resistance to antifungal drug combinationsChanges in the Sterol Composition of the Plasma Membrane Affect Membrane Potential, Salt Tolerance and the Activity of Multidrug Resistance Pumps in Saccharomyces cerevisiaeFrequency-dependent selection and the evolution of assortative matingA genome-wide over-expression screen identifies genes involved in phagocytosis in the human protozoan parasite, Entamoeba histolytica.A microarray-based genetic screen for yeast chronological aging factorsEvaluation of toxicity of the mycotoxin citrinin using yeast ORF DNA microarray and Oligo DNA microarrayEvolutionary divergence in the fungal response to fluconazole revealed by soft clustering.Whole genome duplication affects evolvability of flowering time in an autotetraploid plant.The Celecoxib Derivative AR-12 Has Broad-Spectrum Antifungal Activity In Vitro and Improves the Activity of Fluconazole in a Murine Model of Cryptococcosis.A mutation in Tac1p, a transcription factor regulating CDR1 and CDR2, is coupled with loss of heterozygosity at chromosome 5 to mediate antifungal resistance in Candida albicansGenetic constraints on protein evolutionAntagonism between two mechanisms of antifungal drug resistance.Transcriptional regulation of MDR1, encoding a drug efflux determinant, in fluconazole-resistant Candida albicans strains through an Mcm1p binding siteInvolvement of PDK1, PKC and TOR signalling pathways in basal fluconazole tolerance in Cryptococcus neoformans.Parallel genetic changes and nonparallel gene-environment interactions characterize the evolution of drug resistance in yeast.Phenotypic heterogeneity promotes adaptive evolution.Experimental evolution of pathogenesis: "patient" research.The underlying structure of adaptation under strong selection in 12 experimental yeast populationsEvolutionary dynamics of Candida albicans during in vitro evolution.Ploidy dynamics and evolvability in fungiLysine deacetylases Hda1 and Rpd3 regulate Hsp90 function thereby governing fungal drug resistance.Genomic approach to identification of mutations affecting caspofungin susceptibility in Saccharomyces cerevisiae.Fungal echinocandin resistance.Adaptive walks toward a moving optimum.Haploidy, diploidy and evolution of antifungal drug resistance in Saccharomyces cerevisiaeAneuploidy and isochromosome formation in drug-resistant Candida albicans.Gene expression and evolution of antifungal drug resistance.The Influence of Polyploidy on the Evolution of Yeast Grown in a Sub-Optimal Carbon Source.Sensitivity of White and Opaque Candida albicans Cells to Antifungal Drugs.Dose-dependent selection drives lineage replacement during the experimental evolution of SDHI fungicide resistance in Zymoseptoria tritici.Integrated transcriptomic analysis of Trichosporon Asahii uncovers the core genes and pathways of fluconazole resistance.Loss of Upc2p-Inducible ERG3 Transcription Is Sufficient To Confer Niche-Specific Azole Resistance without Compromising Candida albicans Pathogenicity.Antagonistic pleiotropy for carbon use is rare in new mutations
P2860
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P2860
Mode of selection and experimental evolution of antifungal drug resistance in Saccharomyces cerevisiae
description
2003 nî lūn-bûn
@nan
2003 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Mode of selection and experime ...... ce in Saccharomyces cerevisiae
@ast
Mode of selection and experime ...... ce in Saccharomyces cerevisiae
@en
Mode of selection and experime ...... ce in Saccharomyces cerevisiae
@nl
type
label
Mode of selection and experime ...... ce in Saccharomyces cerevisiae
@ast
Mode of selection and experime ...... ce in Saccharomyces cerevisiae
@en
Mode of selection and experime ...... ce in Saccharomyces cerevisiae
@nl
prefLabel
Mode of selection and experime ...... ce in Saccharomyces cerevisiae
@ast
Mode of selection and experime ...... ce in Saccharomyces cerevisiae
@en
Mode of selection and experime ...... ce in Saccharomyces cerevisiae
@nl
P2093
P2860
P1433
P1476
Mode of selection and experime ...... ce in Saccharomyces cerevisiae
@en
P2093
Ainslie B Parsons
Caroline Sirjusingh
Charles Boone
Claire Wickens
James B Anderson
Leah E Cowen
Linda M Kohn
P2860
P304
P407
P577
2003-04-01T00:00:00Z