Ubiquitin is detected in neurofibrillary tangles and senile plaque neurites of Alzheimer disease brains. - Wikidata - awgldk - TriplyDB

Ubiquitin is detected in neurofibrillary tangles and senile plaque neurites of Alzheimer disease brains.

Ubiquitin is detected in neurofibrillary tangles and senile plaque neurites of Alzheimer disease brains.

http://www.wikidata.org/entity/Q34620363

about

Identification of ubiquilin, a novel presenilin interactor that increases presenilin protein accumulation Mutant ubiquitin (UBB+1) associated with neurodegenerative disorders is hydrolyzed by ubiquitin C-terminal hydrolase L3 (UCH-L3)The human ubiquitin carrier protein E2(Mr = 17,000) is homologous to the yeast DNA repair gene RAD6 Senile plaque neurites in Alzheimer disease accumulate amyloid precursor protein Cloning and sequencing of the cDNA encoding a core protein of the paired helical filament of Alzheimer disease: identification as the microtubule-associated protein tau A method to identify p62’s UBA domain interacting proteins It Is All about (U)biquitin: Role of Altered Ubiquitin-Proteasome System and UCHL1 in Alzheimer Disease Tau Protein Hyperphosphorylation and Aggregation in Alzheimer's Disease and Other Tauopathies, and Possible Neuroprotective Strategies HDAC6 as a target for neurodegenerative diseases: what makes it different from the other HDACs?Cerebrospinal fluid and blood biomarkers in Alzheimer's disease Neuropsychiatric Disturbances in Alzheimer's Disease: What Have We Learned from Neuropathological Studies?Dysregulation of Ubiquitin-Proteasome System in Neurodegenerative Diseases The ubiquitin-like domain of Herp is involved in Herp degradation, but not necessary for its enhancement of amyloid beta-protein generation The Ubiquitin-Proteasome System and Molecular Chaperone Deregulation in Alzheimer's Disease The ubiquitin-proteasome system in Alzheimer's disease Decreased catalytic activity of the insulin-degrading enzyme in chromosome 10-linked Alzheimer disease families The ubiquitin-proteasome pathway and proteasome inhibitors Tau protein kinase I is essential for amyloid beta-protein-induced neurotoxicity Hypothalamic neurodegeneration and adult-onset obesity in mice lacking the Ubb polyubiquitin gene Blood cadmium levels and Alzheimer's disease mortality risk in older US adults Isolation and chemical characterization of Alzheimer's disease paired helical filament cytoskeletons: differentiation from amyloid plaque core protein Abnormal processing of multiple proteins in Alzheimer disease.Transgenic mice overexpressing reticulon 3 develop neuritic abnormalities.Ubiquitination is involved in secondary growth, not initial formation of polyglutamine protein aggregates in C. elegans.Increased levels of oxidative stress markers detected in the brains of mice devoid of prion protein.Casein kinase II alteration precedes tau accumulation in tangle formation Role of the ubiquitin proteasome system in Alzheimer's disease.Neuropathology of Alzheimer's disease Acute ER stress regulates amyloid precursor protein processing through ubiquitin-dependent degradation.Ubiquitin and microtubule-associated protein tau immunoreactivity each define distinct structures with differing distributions and solubility properties in Alzheimer brain.Ubiquitin is a component of the microtubule network Ubiquitin is associated with abnormal cytoplasmic filaments characteristic of neurodegenerative diseases.Diffuse Lewy body disease: correlative neuropathology using anti-ubiquitin immunocytochemistry ATP-induced loss of Alz-50 immunoreactivity with the A68 proteins from Alzheimer brain is mediated by ubiquitin.Alzheimer disease tangles share immunological similarities with multiphosphorylation repeats in the two large neurofilament proteins Protein Quality Control and the Amyotrophic Lateral Sclerosis/Frontotemporal Dementia Continuum Parkin reverses intracellular beta-amyloid accumulation and its negative effects on proteasome function.Vulnerabilities in the tau network and the role of ultrasensitive points in tau pathophysiology.Ubiquitin carboxy-terminal hydrolase L1 (UCHL1) S18Y polymorphism in Alzheimer's disease.Acetylation: a new key to unlock tau's role in neurodegeneration

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P2860

Ubiquitin is detected in neurofibrillary tangles and senile plaque neurites of Alzheimer disease brains.

http://www.wikidata.org/entity/Q34620363

description

1987 nî lūn-bûn

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1987 թուականի Մայիսին հրատարակուած գիտական յօդուած

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1987 թվականի մայիսին հրատարակված գիտական հոդված

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1987年の論文

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1987年論文

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1987年論文

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1987年論文

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1987年論文

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1987年論文

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1987年论文

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name

Ubiquitin is detected in neuro ...... s of Alzheimer disease brains.

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Ubiquitin is detected in neuro ...... s of Alzheimer disease brains.

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Ubiquitin is detected in neuro ...... s of Alzheimer disease brains.

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Ubiquitin is detected in neuro ...... s of Alzheimer disease brains.

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Ubiquitin is detected in neuro ...... s of Alzheimer disease brains.

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Ubiquitin is detected in neuro ...... s of Alzheimer disease brains.

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Ubiquitin is detected in neuro ...... s of Alzheimer disease brains.

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Ubiquitin is detected in neuro ...... s of Alzheimer disease brains.

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Ubiquitin is detected in neuro ...... s of Alzheimer disease brains.

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Proceedings of the National Academy of Sciences of the United States of America

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Ubiquitin is detected in neuro ...... s of Alzheimer disease brains.

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G Perry

http://www.w3.org/2001/XMLSchema#string

G Shaw

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R Friedman

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V Chau

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P2860

Proposed role of ATP in protein breakdown: conjugation of protein with multiple chains of the polypeptide of ATP-dependent proteolysis

Microtubule-associated protein tau (tau) is a major antigenic component of paired helical filaments in Alzheimer disease

The fine structure of some intraganglionic alterations. Neurofibrillary tangles, granulovacuolar bodies and "rod-like" structures as seen in Guam amyotrophic lateral sclerosis and parkinsonism-dementia complex.

Neurofibrillary tangles of Alzheimer disease share antigenic determinants with the axonal microtubule-associated protein tau (tau)

ATP-dependent degradation of ubiquitin-protein conjugates

Conjugation of ubiquitin to denatured hemoglobin is proportional to the rate of hemoglobin degradation in HeLa cells

Paired helical filaments from Alzheimer disease patients contain cytoskeletal components.

The neuropathology of Alzheimer's disease: a review with pathogenetic, aetiological and therapeutic considerations.

Mechanisms of intracellular protein breakdown.

Ubiquitin: roles in protein modification and breakdown.

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9

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Alzheimer's disease

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304795

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