CNT1 expression influences proliferation and chemosensitivity in drug-resistant pancreatic cancer cells - Wikidata - awgldk - TriplyDB

CNT1 expression influences proliferation and chemosensitivity in drug-resistant pancreatic cancer cells

CNT1 expression influences proliferation and chemosensitivity in drug-resistant pancreatic cancer cells

http://www.wikidata.org/entity/Q34621614

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How drugs get into cells: tested and testable predictions to help discriminate between transporter-mediated uptake and lipoidal bilayer diffusion The role of drug transporters in the kidney: lessons from tenofovir Structural basis of nucleoside and nucleoside drug selectivity by concentrative nucleoside transporters Predictive modeling of in vivo response to gemcitabine in pancreatic cancer Pharmacological reversal of histone methylation presensitizes pancreatic cancer cells to nucleoside drugs: in vitro optimization and novel nanoparticle delivery studies Nucleoside transporters and human organic cation transporter 1 determine the cellular handling of DNA-methyltransferase inhibitors.PharmGKB summary: gemcitabine pathway Differential processing of let-7a precursors influences RRM2 expression and chemosensitivity in pancreatic cancer: role of LIN-28 and SET oncoprotein Low expression of the E3 ubiquitin ligase CBL confers chemoresistance in human pancreatic cancer and is targeted by epidermal growth factor receptor inhibition.Nucleoside transporter proteins as biomarkers of drug responsiveness and drug targets.Defective hCNT1 transport contributes to gemcitabine chemoresistance in ovarian cancer subtypes: overcoming transport defects using a nanoparticle approach.Clinical implications of miRNAs in the pathogenesis, diagnosis and therapy of pancreatic cancer.Molecular Imaging of Membrane Transporters' Activity in Cancer: a Picture is Worth a Thousand Tubes.Enhancing Drug Efficacy and Therapeutic Index through Cheminformatics-Based Selection of Small Molecule Binary Weapons That Improve Transporter-Mediated Targeting: A Cytotoxicity System Based on Gemcitabine.Concentrative nucleoside transporter 1 (hCNT1) promotes phenotypic changes relevant to tumor biology in a translocation-independent manner The MUC4 mucin mediates gemcitabine resistance of human pancreatic cancer cells via the Concentrative Nucleoside Transporter family.Vasohibin 2 reduces chemosensitivity to gemcitabine in pancreatic cancer cells via Jun proto-oncogene dependent transactivation of ribonucleotide reductase regulatory subunit M2.Gemcitabine-loaded innovative nanocarriers vs GEMZAR: biodistribution, pharmacokinetic features and in vivo antitumor activity.Drugs in preclinical and early-stage clinical development for pancreatic cancer.Overcoming nucleoside analog chemoresistance of pancreatic cancer: a therapeutic challenge.Gemcitabine-loaded liposomes: rationale, potentialities and future perspectives.Role of solute carrier transporters in pancreatic cancer: a review.MiR-125a regulates chemo-sensitivity to gemcitabine in human pancreatic cancer cells through targeting A20.Noncoding RNAs in Therapeutic Resistance of Cancer.Macrophages mediate gemcitabine resistance of pancreatic adenocarcinoma by upregulating cytidine deaminase.Harnessing Solute Carrier Transporters for Precision Oncology.Integrative genome-wide analysis of the determinants of RNA splicing in kidney renal clear cell carcinoma.SET contributes to the epithelial-mesenchymal transition of pancreatic cancer.Variability of gemcitabine accumulation and its relationship to expression of nucleoside transporters in peripheral blood mononuclear cells.Role of drug-dependent transporter modulation on the chemosensitivity of cholangiocarcinoma.Pancreatic Cancer Chemoresistance to Gemcitabine.The association between the expression of solute carrier transporters and the prognosis of pancreatic cancer.MiR-608 regulating the expression of ribonucleotide reductase M1 and cytidine deaminase is repressed through induced gemcitabine chemoresistance in pancreatic cancer cells.ST6Gal-I sialyltransferase promotes chemoresistance in pancreatic ductal adenocarcinoma by abrogating gemcitabine-mediated DNA damage.Human equilibrative nucleoside transporter 1 gene expression is associated with gemcitabine efficacy in advanced leiomyosarcoma and angiosarcoma.Emerging Roles of Nucleoside Transporters.

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P2860

CNT1 expression influences proliferation and chemosensitivity in drug-resistant pancreatic cancer cells

http://www.wikidata.org/entity/Q34621614

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2011 nî lūn-bûn

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2011 թուականի Փետրուարին հրատարակուած գիտական յօդուած

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2011 թվականի փետրվարին հրատարակված գիտական հոդված

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2011年の論文

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CNT1 expression influences pro ...... istant pancreatic cancer cells

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CNT1 expression influences pro ...... istant pancreatic cancer cells

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CNT1 expression influences pro ...... istant pancreatic cancer cells

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Cancer Research

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CNT1 expression influences pro ...... istant pancreatic cancer cells

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Bhavi Patel

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Dylan Lovin

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Rajgopal Govindarajan

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Sau Wai Hung

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Yangzom D Bhutia

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P2860

BioGPS: an extensible and customizable portal for querying and organizing gene annotation resources.

Loss of FOXA1/2 is essential for the epithelial-to-mesenchymal transition in pancreatic cancer

Up-regulation of miR-200 and let-7 by natural agents leads to the reversal of epithelial-to-mesenchymal transition in gemcitabine-resistant pancreatic cancer cells

Human equilibrative nucleoside transporter 1 levels predict response to gemcitabine in patients with pancreatic cancer.

Expression of the nucleoside-derived drug transporters hCNT1, hENT1 and hENT2 in gynecologic tumors

Regulation of mRNA translation and stability by microRNAs

Pancreatic cancer

S-Phase arrest by nucleoside analogues and abrogation of survival without cell cycle progression by 7-hydroxystaurosporine.

Transcription analysis of human equilibrative nucleoside transporter-1 predicts survival in pancreas cancer patients treated with gemcitabine.

Recent developments in palliative chemotherapy for locally advanced and metastatic pancreas cancer.

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