A natural polymorphism in rDNA replication origins links origin activation with calorie restriction and lifespan
about
The good and the bad of being connected: the integrons of agingThe Epigenetic Pathways to Ribosomal DNA SilencingQuantitative BrdU immunoprecipitation method demonstrates that Fkh1 and Fkh2 are rate-limiting activators of replication origins that reprogram replication timing in G1 phase.Modeling dietary influences on offspring metabolic programming in Drosophila melanogasterThe Nuts and Bolts of Transcriptionally Silent Chromatin in Saccharomyces cerevisiae.Yeast sirtuins and the regulation of aging.The SAGA histone deubiquitinase module controls yeast replicative lifespan via Sir2 interaction.Transgenerational inheritance of diet-induced genome rearrangements in DrosophilaProtocols and programs for high-throughput growth and aging phenotyping in yeast.High Throughput Analyses of Budding Yeast ARSs Reveal New DNA Elements Capable of Conferring Centromere-Independent Plasmid Propagation.Sir2 phosphorylation through cAMP-PKA and CK2 signaling inhibits the lifespan extension activity of Sir2 in yeast.Budding Yeast Rif1 Controls Genome Integrity by Inhibiting rDNA ReplicationMolecular mechanisms governing differential robustness of development and environmental responses in plants.A budding yeast's perspective on aging: the shape I'm in.rDNA Copy Number Variants Are Frequent Passenger Mutations in Saccharomyces cerevisiae Deletion Collections and de Novo Transformants.Global analysis of genomic instability caused by DNA replication stress in Saccharomyces cerevisiaeSIR2 suppresses replication gaps and genome instability by balancing replication between repetitive and unique sequences.An aging-independent replicative lifespan in a symmetrically dividing eukaryote.Evidence for the hallmarks of human aging in replicatively aging yeast.Drugs that modulate aging: the promising yet difficult path ahead.Budding yeast as a model organism to study the effects of age.The fine line between lifespan extension and shortening in response to caloric restriction.Drosophila melanogaster: An emerging model of transgenerational effects of maternal obesity.Dietary restriction and lifespan: Lessons from invertebrate models.Unbalanced Growth, Senescence and Aging.DNA replication stress restricts ribosomal DNA copy number.The cohesin acetyltransferase Eco1 coordinates rDNA replication and transcription.Absence of Non-histone Protein Complexes at Natural Chromosomal Pause Sites Results in Reduced Replication Pausing in Aging Yeast Cells.Defective replication initiation results in locus specific chromosome breakage and a ribosomal RNA deficiency in yeast.An interplay between multiple sirtuins promotes completion of DNA replication in cells with short telomeres.Effect of temperature on replicative aging of the budding yeast Saccharomyces cerevisiae.Yeast heterochromatin regulators Sir2 and Sir3 act directly at euchromatic DNA replication origins.
P2860
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P2860
A natural polymorphism in rDNA replication origins links origin activation with calorie restriction and lifespan
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2013 nî lūn-bûn
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2013 թուականի Մարտին հրատարակուած գիտական յօդուած
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2013 թվականի մարտին հրատարակված գիտական հոդված
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2013年の論文
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2013年論文
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2013年論文
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2013年論文
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2013年論文
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2013年論文
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2013年论文
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name
A natural polymorphism in rDNA ...... lorie restriction and lifespan
@ast
A natural polymorphism in rDNA ...... lorie restriction and lifespan
@en
A natural polymorphism in rDNA ...... lorie restriction and lifespan
@nl
type
label
A natural polymorphism in rDNA ...... lorie restriction and lifespan
@ast
A natural polymorphism in rDNA ...... lorie restriction and lifespan
@en
A natural polymorphism in rDNA ...... lorie restriction and lifespan
@nl
prefLabel
A natural polymorphism in rDNA ...... lorie restriction and lifespan
@ast
A natural polymorphism in rDNA ...... lorie restriction and lifespan
@en
A natural polymorphism in rDNA ...... lorie restriction and lifespan
@nl
P2093
P2860
P1433
P1476
A natural polymorphism in rDNA ...... lorie restriction and lifespan
@en
P2093
Antonio Bedalov
Bonita J Brewer
Brian K Kennedy
Elizabeth X Kwan
Eric J Foss
Gina M Alvino
Leonid Kruglyak
M K Raghuraman
Scott Tsuchiyama
P2860
P304
P356
10.1371/JOURNAL.PGEN.1003329
P577
2013-03-07T00:00:00Z