Abnormal mitochondrial dynamics, mitochondrial loss and mutant huntingtin oligomers in Huntington's disease: implications for selective neuronal damage. - Wikidata - awgldk - TriplyDB

Abnormal mitochondrial dynamics, mitochondrial loss and mutant huntingtin oligomers in Huntington's disease: implications for selective neuronal damage.

Abnormal mitochondrial dynamics, mitochondrial loss and mutant huntingtin oligomers in Huntington's disease: implications for selective neuronal damage.

http://www.wikidata.org/entity/Q34627072

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Identification of novel molecular markers for prognosis estimation of acute myeloid leukemia: over-expression of PDCD7, FIS1 and Ang2 may indicate poor prognosis in pretreatment patients with acute myeloid leukemia LRRK2 regulates mitochondrial dynamics and function through direct interaction with DLP1 Adaptor proteins MiD49 and MiD51 can act independently of Mff and Fis1 in Drp1 recruitment and are specific for mitochondrial fission.Role of telomere dysfunction in cardiac failure in Duchenne muscular dystrophy Charcot-Marie-Tooth disease and intracellular traffic The choreography of neuroinflammation in Huntington's disease Physiological and pathological significance of dynamin-related protein 1 (drp1)-dependent mitochondrial fission in the nervous system PGC-1α, mitochondrial dysfunction, and Huntington's disease Impaired mitochondrial dynamics and Nrf2 signaling contribute to compromised responses to oxidative stress in striatal cells expressing full-length mutant huntingtin Alterations of mitochondrial dynamics allow retrograde propagation of locally initiated axonal insults Huntington's disease induced cardiac amyloidosis is reversed by modulating protein folding and oxidative stress pathways in the Drosophila heart Ubiquitin-dependent mitochondrial protein degradation.Mitochondrial Biology and Neurological Diseases Abnormal interaction between the mitochondrial fission protein Drp1 and hyperphosphorylated tau in Alzheimer's disease neurons: implications for mitochondrial dysfunction and neuronal damage Shaping the role of mitochondria in the pathogenesis of Huntington's disease Mitochondrial dysfunction in neurodegenerative diseases Biophysical insights into how surfaces, including lipid membranes, modulate protein aggregation related to neurodegeneration.Metabolic profiling for the identification of Huntington biomarkers by on-line solid-phase extraction capillary electrophoresis mass spectrometry combined with advanced data analysis tools.Decreased O-linked GlcNAcylation protects from cytotoxicity mediated by huntingtin exon1 protein fragment D-β-hydroxybutyrate is protective in mouse models of Huntington's disease.Huntingtin protein interactions altered by polyglutamine expansion as determined by quantitative proteomic analysis.The optic nerve: a "mito-window" on mitochondrial neurodegeneration Increased mitochondrial fission and neuronal dysfunction in Huntington's disease: implications for molecular inhibitors of excessive mitochondrial fission Dysfunctional mitochondrial respiration in the striatum of the Huntington's disease transgenic R6/2 mouse model.TOM40 mediates mitochondrial dysfunction induced by α-synuclein accumulation in Parkinson's disease.Impaired mitochondrial dynamics and abnormal interaction of amyloid beta with mitochondrial protein Drp1 in neurons from patients with Alzheimer's disease: implications for neuronal damage.Assessment of newly synthesized mitochondrial DNA using BrdU labeling in primary neurons from Alzheimer's disease mice: Implications for impaired mitochondrial biogenesis and synaptic damage.Aging and amyloid beta-induced oxidative DNA damage and mitochondrial dysfunction in Alzheimer's disease: implications for early intervention and therapeutics.Mutant huntingtin, abnormal mitochondrial dynamics, defective axonal transport of mitochondria, and selective synaptic degeneration in Huntington's disease Implications of mitochondrial dynamics on neurodegeneration and on hypothalamic dysfunction.Mutant huntingtin's interaction with mitochondrial protein Drp1 impairs mitochondrial biogenesis and causes defective axonal transport and synaptic degeneration in Huntington's disease.Dynamin-related protein 1 heterozygote knockout mice do not have synaptic and mitochondrial deficiencies Oxidative metabolism in YAC128 mouse model of Huntington's disease.The emerging role of proteolysis in mitochondrial quality control and the etiology of Parkinson's disease.GSK-3β-induced Tau pathology drives hippocampal neuronal cell death in Huntington's disease: involvement of astrocyte-neuron interactions Mitochondria-targeted catalase reduces abnormal APP processing, amyloid β production and BACE1 in a mouse model of Alzheimer's disease: implications for neuroprotection and lifespan extension.Dithiol-based compounds maintain expression of antioxidant protein peroxiredoxin 1 that counteracts toxicity of mutant huntingtin.Mitochondria: the next (neurode)generation Novel Metabolic Abnormalities in the Tricarboxylic Acid Cycle in Peripheral Cells From Huntington's Disease Patients Impaired GAPDH-induced mitophagy contributes to the pathology of Huntington's disease.

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Abnormal mitochondrial dynamics, mitochondrial loss and mutant huntingtin oligomers in Huntington's disease: implications for selective neuronal damage.

http://www.wikidata.org/entity/Q34627072

description

2011 nî lūn-bûn

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2011 թուականի Յունուարին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի հունվարին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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name

Abnormal mitochondrial dynamic ...... for selective neuronal damage.

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Abnormal mitochondrial dynamic ...... for selective neuronal damage.

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Abnormal mitochondrial dynamic ...... for selective neuronal damage.

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type

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Abnormal mitochondrial dynamic ...... for selective neuronal damage.

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Abnormal mitochondrial dynamic ...... for selective neuronal damage.

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Abnormal mitochondrial dynamic ...... for selective neuronal damage.

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prefLabel

Abnormal mitochondrial dynamic ...... for selective neuronal damage.

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Abnormal mitochondrial dynamic ...... for selective neuronal damage.

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Abnormal mitochondrial dynamic ...... for selective neuronal damage.

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Human Molecular Genetics

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Abnormal mitochondrial dynamic ...... for selective neuronal damage.

@en

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Arubala P Reddy

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Danilo A Tagle

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Marcus J Calkins

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Maria Manczak

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P Hemachandra Reddy

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Peizhong Mao

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Ulziibat Shirendeb

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P2860

Loss of PINK1 function promotes mitophagy through effects on oxidative stress and mitochondrial fission

Huntingtin has a membrane association signal that can modulate huntingtin aggregation, nuclear entry and toxicity

Brain imaging and cognitive dysfunctions in Huntington's disease

Dynamin-related protein 1 and mitochondrial fragmentation in neurodegenerative diseases

Mutant huntingtin impairs axonal trafficking in mammalian neurons in vivo and in vitro

Impaired balance of mitochondrial fission and fusion in Alzheimer's disease

Trinucleotide Repeat Disorders

Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis

The PINK1/Parkin pathway regulates mitochondrial morphology

The Parkinson's disease genes pink1 and parkin promote mitochondrial fission and/or inhibit fusion in Drosophila

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10.1093/HMG/DDR024

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7

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20

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2011-01-21T00:00:00Z

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49776858

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21257639

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Huntington disease

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3049363

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