Targeted inhibition of mitochondrial Hsp90 suppresses localised and metastatic prostate cancer growth in a genetic mouse model of disease.
about
Molecular chaperone TRAP1 regulates a metabolic switch between mitochondrial respiration and aerobic glycolysisLysosomotropic properties of weakly basic anticancer agents promote cancer cell selectivity in vitroGetting personal with prostate cancer: adding new pieces to an incomplete jigsaw puzzle.Cytosolic Hsp90α and its mitochondrial isoform Trap1 are differentially required in a breast cancer model.Combination treatment with doxorubicin and gamitrinib synergistically augments anticancer activity through enhanced activation of Bim.Deregulation of MiR-34b/Sox2 Predicts Prostate Cancer Progression.Recent progress in targeting cancer.Targeting cancer cell mitochondria as a therapeutic approach.Control of tumor bioenergetics and survival stress signaling by mitochondrial HSP90s.Hsp90 regulation of mitochondrial protein folding: from organelle integrity to cellular homeostasisTRAP-1, the mitochondrial Hsp90.Targeting malignant mitochondria with therapeutic peptides.Oncogene and non-oncogene addiction in inflammation-associated cancers.TRAP1: a viable therapeutic target for future cancer treatments?Genome-wide in vivo screen identifies novel host regulators of metastatic colonization.Inhibition of stress-inducible HSP70 impairs mitochondrial proteostasis and function.TRAP1 and the proteasome regulatory particle TBP7/Rpt3 interact in the endoplasmic reticulum and control cellular ubiquitination of specific mitochondrial proteins.Mitochondrial heat shock protein-90 modulates vascular smooth muscle cell survival and the vascular injury response in vivo.Inhibition of Mitochondrial Matrix Chaperones and Antiapoptotic Bcl-2 Family Proteins Empower Antitumor Therapeutic Responses.
P2860
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P2860
Targeted inhibition of mitochondrial Hsp90 suppresses localised and metastatic prostate cancer growth in a genetic mouse model of disease.
description
2011 nî lūn-bûn
@nan
2011 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Targeted inhibition of mitocho ...... enetic mouse model of disease.
@ast
Targeted inhibition of mitocho ...... enetic mouse model of disease.
@en
Targeted inhibition of mitocho ...... enetic mouse model of disease.
@nl
type
label
Targeted inhibition of mitocho ...... enetic mouse model of disease.
@ast
Targeted inhibition of mitocho ...... enetic mouse model of disease.
@en
Targeted inhibition of mitocho ...... enetic mouse model of disease.
@nl
prefLabel
Targeted inhibition of mitocho ...... enetic mouse model of disease.
@ast
Targeted inhibition of mitocho ...... enetic mouse model of disease.
@en
Targeted inhibition of mitocho ...... enetic mouse model of disease.
@nl
P2093
P2860
P356
P1476
Targeted inhibition of mitocho ...... genetic mouse model of disease
@en
P2093
C M Raskett
D C Altieri
D S Garlick
M Tavecchio
P2860
P2888
P304
P356
10.1038/BJC.2011.9
P407
P577
2011-02-01T00:00:00Z
P5875
P6179
1027420715