The complexities of p97 function in health and disease - Wikidata - awgldk - TriplyDB

The complexities of p97 function in health and disease

The complexities of p97 function in health and disease

http://www.wikidata.org/entity/Q34632255

about

NMR characterization of the interaction between the PUB domain of peptide:N-glycanase and ubiquitin-like domain of HR23 Targeting p97 to Disrupt Protein Homeostasis in Cancer Protein folding and quality control in the ER Withaferin A Analogs That Target the AAA+ Chaperone p97.Selective inhibition of p97 by chlorinated analogues of dehydrocurvularin Functional chromatography reveals three natural products that target the same protein with distinct mechanisms of action.Evaluating p97 inhibitor analogues for their domain selectivity and potency against the p97-p47 complex.Requirements for mouse mammary tumor virus Rem signal peptide processing and function Arginine methylation of HSP70 regulates retinoid acid-mediated RARβ2 gene activation Interprotomer motion-transmission mechanism for the hexameric AAA ATPase p97.Simulations of the p97 complex suggest novel conformational states of hydrolysis intermediates Dynamic flexibility of the ATPase p97 is important for its interprotomer motion transmission.Inhibitors of the AAA+ chaperone p97 Lysine Methylation of the Valosin-Containing Protein (VCP) Is Dispensable for Development and Survival of Mice.Ubiquitination of the N-terminal region of caveolin-1 regulates endosomal sorting by the VCP/p97 AAA-ATPase Dual Unnatural Amino Acid Incorporation and Click-Chemistry Labeling to Enable Single-Molecule FRET Studies of p97 Folding.UBXN1 interferes with Rig-I-like receptor-mediated antiviral immune response by targeting MAVS.Oxaspirol B with p97 Inhibitory Activity and Other Oxaspirols from Lecythophora sp. FL1375 and FL1031, Endolichenic Fungi Inhabiting Parmotrema tinctorum and Cladonia evansii.Pathogenic Mutations in the Valosin-containing Protein/p97(VCP) N-domain Inhibit the SUMOylation of VCP and Lead to Impaired Stress Response.Interaction between salt-inducible kinase 2 (SIK2) and p97/valosin-containing protein (VCP) regulates endoplasmic reticulum (ER)-associated protein degradation in mammalian cells.Mouse Mammary Tumor Virus Signal Peptide Uses a Novel p97-Dependent and Derlin-Independent Retrotranslocation Mechanism To Escape Proteasomal Degradation.Neurodegeneration as a consequence of failed mitochondrial maintenance.Inter-ring rotations of AAA ATPase p97 revealed by electron cryomicroscopy.Origin and Functional Evolution of the Cdc48/p97/VCP AAA+ Protein Unfolding and Remodeling Machine.Ubiquitin- and ATP-dependent unfoldase activity of P97/VCP•NPLOC4•UFD1L is enhanced by a mutation that causes multisystem proteinopathy.p97 Negatively Regulates NRF2 by Extracting Ubiquitylated NRF2 from the KEAP1-CUL3 E3 Complex.Valosin-containing Protein is a Target of 5'-l Fuligocandin B and Enhances TRAIL Resistance in Cancer Cells.Protein-Protein Interface and Disease: Perspective from Biomolecular Networks.The p97-FAF1 protein complex reveals a common mode of p97 adaptor binding.The Interplay of Cofactor Interactions and Post-translational Modifications in the Regulation of the AAA+ ATPase p97.Perturbations to the ubiquitin conjugate proteome in yeast δubx mutants identify Ubx2 as a regulator of membrane lipid composition.Targeting protein quality control pathways in breast cancer.Is amyotrophic lateral sclerosis/frontotemporal dementia an autophagy disease?Interaction between the AAA+ ATPase p97 and its cofactor ataxin3 in health and disease: Nucleotide-induced conformational changes regulate cofactor binding.Molecular Mechanism of Substrate Processing by the Cdc48 ATPase Complex.Association between SNPs and haplotypes in the METTL21C gene and peak bone mineral density and body composition in Chinese male nuclear families.Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.Evaluating p97 Inhibitor Analogues for Potency against p97-p37 and p97-Npl4-Ufd1 Complexes.

P2860

Q24320023-DC14F6FF-8D2E-452C-AD2A-F03C74C4D0F2 Q26740517-77C055A5-1792-4EB7-90EC-77AB496B2CA6 Q26823157-85F76929-6032-4F99-A230-81CC9A344B10 Q33360763-F3B64CBD-D02E-400F-B15E-A43E2E65324A Q33785301-E25C4E16-5AF5-48FE-B6E4-C110020EAE4E Q34295600-54762334-AF6B-4464-A8A4-8D410DFA6E28 Q34791483-42295EA9-0C7D-4429-9CAD-594311035784 Q35666074-9F0A2218-70A8-420F-85AF-6AA94A4D647F Q35818709-49492A9C-AC10-4D7F-B123-AA3807815241 Q35844874-2D9A5D96-D5C9-4A24-A68F-8F91CE0A2D9A Q36033903-B9721CB5-0BF4-4422-9DFD-424FB39C3094 Q36056343-203121C4-7CBB-4A8D-B0B1-43C842BFD07A Q36078289-D6F29D2C-E2E9-4978-9910-1B599D9AB4ED Q36257300-A53DFEDF-AA47-49AD-B928-BE83E29705AF Q36666294-CDCBDFEA-3D54-4138-A889-3F3112B76C28 Q36997177-F0FA492E-9CD1-4CF6-9BCD-009159664FE2 Q36998981-4FD440B8-A9F7-4EE4-8932-18CD99F3C35E Q37051141-C451DAD4-C6C6-442A-A130-99DD5A84BBFE Q37065788-A67BDBB6-E2DC-43C5-9740-94C66F603AFE Q37333755-6E0AD00B-FBEC-4D37-9EE2-6BB799574CF7 Q37727169-CB2FB4BE-F1C9-488C-AD2A-C1E5554D927F Q37965012-CEF2A8FB-B2C5-4F39-9C09-00DE472D0FDF Q38576097-4272BC3F-A24F-491D-9504-F05922E103DC Q38648242-2601F612-B818-4AF7-9EE4-BD641C9D2147 Q38682988-4C670ECA-3BCE-4A22-B9AC-0D4BED9653E6 Q38719829-F4102EBF-E18A-480F-BC18-A03C5FD85D8A Q38723897-90EA0565-D980-4B73-AE9F-257F58CCF652 Q38785911-835AC915-40D2-47F1-9FB8-1ADAC4D4605A Q39007131-3A8CBF51-8586-44DD-897C-197C55867CBB Q39268583-0675DFE9-9AF3-47B0-85B3-78B02B71D091 Q39398325-AF08C8DE-2365-47F8-8F29-24263E2D0F9C Q46087491-7DD95ABC-20A2-4E32-8D31-BA17B9C0D57E Q47108927-4BB367C9-1F2C-4AF5-A248-0BBA46CF4981 Q47758356-2E5EDCE0-BD6E-4C2D-9B5A-F138AD8284AA Q51018275-605A9F70-CDB6-405A-ADA1-682B25F9B971 Q51810405-38E3AE0E-EDF4-44F2-A932-B406406FB023 Q52731173-A02476AD-9A5C-4288-B5CE-A7A932BA29D6 Q53161512-7B3A725B-242C-4360-8E76-632FEAC28EA3

P2860

The complexities of p97 function in health and disease

http://www.wikidata.org/entity/Q34632255

description

2010 nî lūn-bûn

@nan

2010 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի դեկտեմբերին հրատարակված գիտական հոդված

@hy

2010年の論文

@ja

2010年論文

@yue

2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

@wuu

name

The complexities of p97 function in health and disease

@ast

The complexities of p97 function in health and disease

@en

The complexities of p97 function in health and disease

@nl

type

label

The complexities of p97 function in health and disease

@ast

The complexities of p97 function in health and disease

@en

The complexities of p97 function in health and disease

@nl

prefLabel

The complexities of p97 function in health and disease

@ast

The complexities of p97 function in health and disease

@en

The complexities of p97 function in health and disease

@nl

P1433

Q34632255-B1B8AE2E-7FB4-44DA-BAA6-9763D98897BA

P1476

Q34632255-EB399CDF-FC49-4D5C-9237-671BD7DC39F7

P2093

Q34632255-2276BC44-6CDE-45A3-B544-1A59B69FFCB2

Q34632255-EE03822F-ACFE-4539-BBCB-B53FB8178DF6

Q34632255-F0D714BD-7944-4F93-9A6D-BAC216970142

P2860

Q34632255-0136AEC4-2C76-4A21-917E-97AE50591FD9

Q34632255-066A9790-E8C8-451F-B289-37543E5F4A97

Q34632255-0B49D0B7-A747-4990-B1EC-C552D3125723

Q34632255-0CD625EA-6FBB-4DEF-A400-D8A072171C81

Q34632255-0E5BCB5C-7A5B-4025-8373-DB652602C8D8

Q34632255-1213B88A-3180-4094-B238-CEBE6424AC17

Q34632255-129A1C7D-16AB-4069-AB45-29BEDBAEAA95

Q34632255-15C19565-8AFF-467D-9D2A-BBC14B5F85CB

Q34632255-17498DD1-9A53-4295-B4D1-19A716171D15

Q34632255-175977CA-6E12-497D-9E13-8B876E4B8357

P304

Q34632255-39E3921A-0E86-4398-AB8F-F4FB94F40F9D

P31

Q34632255-9C030563-C528-4A07-98F0-9C3DE1AD1F6B

Q34632255-9bdd4e96-0b2b-48b0-97b1-53c362568d76

P356

Q34632255-FBD45408-3C49-4E65-A686-E19D0822C2C6

P433

Q34632255-BDFD57AE-773D-48B9-AC3A-2F26998261E4

P478

Q34632255-59616637-BA0D-41D0-8573-57E0ED9C0484

P577

Q34632255-19963669-C822-4771-9D15-722DB338E25C

P5875

Q34632255-8E73893C-A14B-4CFE-A7D9-341AB76B8FF6

P698

Q34632255-C26A44A3-41B0-4E19-90B6-3E404E8FF85C

P932

Q34632255-8BB1AFB2-523D-4EE9-8553-E2EC14D9DBDB

P356

P1433

Molecular BioSystems

P1476

The complexities of p97 function in health and disease

@en

P2093

Anastasia N Fry

http://www.w3.org/2001/XMLSchema#string

Eli Chapman

http://www.w3.org/2001/XMLSchema#string

MinJin Kang

http://www.w3.org/2001/XMLSchema#string

P2860

Familial Parkinson disease gene product, parkin, is a ubiquitin-protein ligase

Identification of SVIP as an endogenous inhibitor of endoplasmic reticulum-associated degradation

Human Fas-associated factor 1, interacting with ubiquitinated proteins and valosin-containing protein, is involved in the ubiquitin-proteasome pathway

A membrane protein complex mediates retro-translocation from the ER lumen into the cytosol

Class II histone deacetylases: versatile regulators

The deacetylase HDAC6 regulates aggresome formation and cell viability in response to misfolded protein stress

An arginine/lysine-rich motif is crucial for VCP/p97-mediated modulation of ataxin-3 fibrillogenesis.

Function of the p97-Ufd1-Npl4 complex in retrotranslocation from the ER to the cytosol: dual recognition of nonubiquitinated polypeptide segments and polyubiquitin chains

UBXD7 binds multiple ubiquitin ligases and implicates p97 in HIF1alpha turnover

Involvement of valosin-containing protein, an ATPase Co-purified with IkappaBalpha and 26 S proteasome, in ubiquitin-proteasome-mediated degradation of IkappaBalpha

P304

700-710

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1039/C0MB00176G

http://www.w3.org/2001/XMLSchema#string

P433

3

http://www.w3.org/2001/XMLSchema#string

P478

7

http://www.w3.org/2001/XMLSchema#string

P577

2010-12-14T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

49678329

http://www.w3.org/2001/XMLSchema#string

P698

21152665

http://www.w3.org/2001/XMLSchema#string

P932

3050576

http://www.w3.org/2001/XMLSchema#string