A yeast chemical genetic screen identifies inhibitors of human telomerase. - Wikidata - awgldk - TriplyDB

A yeast chemical genetic screen identifies inhibitors of human telomerase.

A yeast chemical genetic screen identifies inhibitors of human telomerase.

http://www.wikidata.org/entity/Q34632410

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Therapeutic Targeting of Telomerase Therapeutic targeting of replicative immortality Efforts to make and apply humanized yeast Systematic chemical-genetic and chemical-chemical interaction datasets for prediction of compound synergism Panspecies small-molecule disruptors of heterochromatin-mediated transcriptional gene silencing.Angiotensin II type 1 receptor blockers increase tolerance of cells to copper and cisplatin.BRD4 inhibitors block telomere elongation.How Surrogate and Chemical Genetics in Model Organisms Can Suggest Therapies for Human Genetic Diseases.

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A yeast chemical genetic screen identifies inhibitors of human telomerase.

http://www.wikidata.org/entity/Q34632410

description

2013 nî lūn-bûn

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2013 թուականի Մարտին հրատարակուած գիտական յօդուած

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2013 թվականի մարտին հրատարակված գիտական հոդված

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2013年の論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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2013年论文

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name

A yeast chemical genetic screen identifies inhibitors of human telomerase.

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A yeast chemical genetic screen identifies inhibitors of human telomerase.

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A yeast chemical genetic screen identifies inhibitors of human telomerase.

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type

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A yeast chemical genetic screen identifies inhibitors of human telomerase.

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A yeast chemical genetic screen identifies inhibitors of human telomerase.

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A yeast chemical genetic screen identifies inhibitors of human telomerase.

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prefLabel

A yeast chemical genetic screen identifies inhibitors of human telomerase.

@ast

A yeast chemical genetic screen identifies inhibitors of human telomerase.

@en

A yeast chemical genetic screen identifies inhibitors of human telomerase.

@nl

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J.CHEMBIOL.2012.12.008

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Chemistry and Biology

P1476

A yeast chemical genetic screen identifies inhibitors of human telomerase.

@en

P2093

Lea Harrington

http://www.w3.org/2001/XMLSchema#string

Mike Tyers

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Rachel White

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P2860

Polymerization defects within human telomerase are distinct from telomerase RNA and TEP1 binding

Human telomerase contains evolutionarily conserved catalytic and structural subunits

Esc4p, a new target of Mec1p (ATR), promotes resumption of DNA synthesis after DNA damage.

A suppressor of two essential checkpoint genes identifies a novel protein that negatively affects dNTP pools.

Reconstitution of human telomerase activity in vitro

Identification of biologically active PDE11-selective inhibitors using a yeast-based high-throughput screen

Telomere shortening sensitizes cancer cells to selected cytotoxic agents: in vitro and in vivo studies and putative mechanisms

A highly selective telomerase inhibitor limiting human cancer cell proliferation

Transformation of yeast by lithium acetate/single-stranded carrier DNA/polyethylene glycol method

The N-terminus of hTERT contains a DNA-binding domain and is required for telomerase activity and cellular immortalization

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333-340

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scholarly article

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10.1016/J.CHEMBIOL.2012.12.008

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3

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20

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Asier Unciti-Broceta

Michaela Spitzer

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2013-03-01T00:00:00Z

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236073649

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