Comparative preclinical activity of the folate-targeted Vinca alkaloid conjugates EC140 and EC145.
about
Phase I study of folate conjugate EC145 (Vintafolide) in patients with refractory solid tumors.Intracellular trafficking considerations in the development of natural ligand-drug molecular conjugates for cancer.Folate receptor-mediated enhanced and specific delivery of far-red light-activatable prodrugs of combretastatin A-4 to FR-positive tumorFolate receptor-α (FOLR1) expression and function in triple negative tumorsSelective Tumor Targeting of Desacetyl Vinblastine Hydrazide and Tubulysin B via Conjugation to a Cholecystokinin 2 Receptor (CCK2R) LigandVintafolide: a novel targeted therapy for the treatment of folate receptor expressing tumors.Clinical pharmacokinetics and exposure-toxicity relationship of a folate-Vinca alkaloid conjugate EC145 in cancer patientsFolate receptor alpha as a tumor target in epithelial ovarian cancerTargeted treatment of folate receptor-positive platinum-resistant ovarian cancer and companion diagnostics, with specific focus on vintafolide and etarfolatide.EC145: a novel targeted agent for adenocarcinoma of the lung.Vintafolide (EC145) for the treatment of folate-receptor-α positive platinum-resistant ovarian cancer.Targeting the folate receptor: diagnostic and therapeutic approaches to personalize cancer treatments.Small Molecules for Active Targeting in Cancer.Enhancing the therapeutic range of a targeted small-molecule tubulysin conjugate for folate receptor-based cancer therapy.Serum folate receptor alpha as a biomarker for ovarian cancer: Implications for diagnosis, prognosis and predicting its local tumor expression.Folate Receptor-Positive Gynecological Cancer Cells: In Vitro and In Vivo Characterization.Carbon nanotubes functionalized with folic acid attached via biomimetic peptide linker.Accessing Structurally Diverse Near-Infrared Cyanine Dyes for Folate Receptor-Targeted Cancer Cell Staining.Phase II study of treatment of advanced ovarian cancer with folate-receptor-targeted therapeutic (vintafolide) and companion SPECT-based imaging agent (99mTc-etarfolatide).
P2860
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P2860
Comparative preclinical activity of the folate-targeted Vinca alkaloid conjugates EC140 and EC145.
description
2007 nî lūn-bûn
@nan
2007 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Comparative preclinical activi ...... id conjugates EC140 and EC145.
@ast
Comparative preclinical activi ...... id conjugates EC140 and EC145.
@en
Comparative preclinical activi ...... id conjugates EC140 and EC145.
@nl
type
label
Comparative preclinical activi ...... id conjugates EC140 and EC145.
@ast
Comparative preclinical activi ...... id conjugates EC140 and EC145.
@en
Comparative preclinical activi ...... id conjugates EC140 and EC145.
@nl
prefLabel
Comparative preclinical activi ...... id conjugates EC140 and EC145.
@ast
Comparative preclinical activi ...... id conjugates EC140 and EC145.
@en
Comparative preclinical activi ...... id conjugates EC140 and EC145.
@nl
P2093
P356
P1476
Comparative preclinical activi ...... id conjugates EC140 and EC145.
@en
P2093
Christopher P Leamon
Elaine Westrick
Iontcho R Vlahov
Jeffrey S Nicoson
Joseph A Reddy
Marilynn Vetzel
Nikki Parker
P304
P356
10.1002/IJC.22853
P577
2007-10-01T00:00:00Z