Translational evaluation of JNJ-18038683, a 5-hydroxytryptamine type 7 receptor antagonist, on rapid eye movement sleep and in major depressive disorder.

Translational evaluation of JNJ-18038683, a 5-hydroxytryptamine type 7 receptor antagonist, on rapid eye movement sleep and in major depressive disorder.

Item
http://www.wikidata.org/entity/Q34638155
Profile of vortioxetine in the treatment of major depressive disorder: an overview of the primary and secondary literatureManagement of bipolar I depression: clinical utility of lurasidoneTargeting the Serotonin 5-HT7 Receptor in the Search for Treatments for CNS Disorders: Rationale and Progress to DateThe serotonin 5-HT7 receptors: two decades of research.Interplay between serotonin 5-HT1A and 5-HT7 receptors in depressive disorders.Differentiated effects of the multimodal antidepressant vortioxetine on sleep architecture: Part 2, pharmacological interactions in rodents suggest a role of serotonin-3 receptor antagonism.Differentiated effects of the multimodal antidepressant vortioxetine on sleep architecture: Part 1, a pharmacokinetic/pharmacodynamic comparison with paroxetine in healthy men.Five potential therapeutic agents as antidepressants: a brief review and future directions.The arylpiperazine derivatives N-(4-cyanophenylmethyl)-4-(2-diphenyl)-1-piperazinehexanamide and N-benzyl-4-(2-diphenyl)-1-piperazinehexanamide exert a long-lasting inhibition of human serotonin 5-HT7 receptor binding and cAMP signaling.Selective pharmacological blockade of the 5-HT7 receptor attenuates light and 8-OH-DPAT induced phase shifts of mouse circadian wheel running activity.5-Hydroxytryptamine type 7 receptor neuroprotection against NMDA-induced excitotoxicity is PDGFβ receptor dependent.Asenapine modulates mood-related behaviors and 5-HT1A/7 receptors-mediated neurotransmission.In the search for a lead structure among series of potent and selective hydantoin 5-HT7 R agents: The drug-likeness in vitro study.The sleep effects of lurasidone: a placebo-controlled cross-over study using a 4-h phase-advance model of transient insomnia.Towards metabolically stable 5-HT7 receptor ligands: a study on 1-arylpiperazine derivatives and related isosters.Arylsulfonamide derivatives of (aryloxy)ethylpiperidines as selective 5-HT7 receptor antagonists and their psychotropic properties
P2860

Translational evaluation of JNJ-18038683, a 5-hydroxytryptamine type 7 receptor antagonist, on rapid eye movement sleep and in major depressive disorder.

Item
http://www.wikidata.org/entity/Q34638155
description
2012 nî lūn-bûn
@nan
2012 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի մայիսին հրատարակված գիտական հոդված
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2012年の論文
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2012年論文
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2012年論文
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2012年論文
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2012年論文
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2012年論文
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2012年论文
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name
Translational evaluation of JN ...... in major depressive disorder.
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Translational evaluation of JN ...... in major depressive disorder.
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Translational evaluation of JN ...... in major depressive disorder.
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type
label
Translational evaluation of JN ...... in major depressive disorder.
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Translational evaluation of JN ...... in major depressive disorder.
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Translational evaluation of JN ...... in major depressive disorder.
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prefLabel
Translational evaluation of JN ...... in major depressive disorder.
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Translational evaluation of JN ...... in major depressive disorder.
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Translational evaluation of JN ...... in major depressive disorder.
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Translational evaluation of JN ...... d in major depressive disorder
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P2093
P304
P31
P356
P407
P433
P478
P50
P577
P5875
P698