Species difference in the inhibitory effect of nonsteroidal anti-inflammatory drugs on the uptake of methotrexate by human kidney slices.
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OATPs, OATs and OCTs: the organic anion and cation transporters of the SLCO and SLC22A gene superfamiliesThe Safety and Pharmacokinetics of Carprofen, Flunixin and Phenylbutazone in the Cape Vulture (Gyps coprotheres) following Oral ExposureExtra-renal elimination of uric acid via intestinal efflux transporter BCRP/ABCG2To scale or not to scale: the principles of dose extrapolationMembrane transporters in drug developmentDeregulated hepatic metabolism exacerbates impaired testosterone production in Mrp4-deficient mice.Machine learning workflow to enhance predictions of Adverse Drug Reactions (ADRs) through drug-gene interactions: application to drugs for cutaneous diseasesFluorescence-based assays for the assessment of drug interaction with the human transporters OATP1B1 and OATP1B3Urinary coproporphyrin I/(I + III) ratio as a surrogate for MRP2 or other transporter activities involved in methotrexate clearance.The pharmacokinetic effect of coadministration of apremilast and methotrexate in individuals with rheumatoid arthritis and psoriatic arthritisWhat do drug transporters really do?Co-administration of proton pump inhibitors delays elimination of plasma methotrexate in high-dose methotrexate therapy.Effects of pharmaceuticals and other active chemicals at biological targets: mechanisms, interactions, and integration into PB-PK/PD models.Clinical analysis of chinese patients with rheumatoid arthritis treated with leflunomide and methotrexate combined with different dosages of glucocorticoidTransporter-mediated drug-drug interactions.Pharmacokinetic drug-drug interactions with methotrexate in oncology.Mechanisms and therapeutic potential of inhibiting drug efflux transporters.Modulators of the human ABCC2: hope from natural sources?Pharmacogenetics of irinotecan, doxorubicin and docetaxel transporters in Asian and Caucasian cancer patients: a comparative review.Transport rankings of non-steroidal antiinflammatory drugs across blood-brain barrier in vitro models.Renal Drug Transporters and Drug Interactions.Allometric Scaling of Clearance in Paediatric Patients: When Does the Magic of 0.75 Fade?Microdose study of 14C-acetaminophen with accelerator mass spectrometry to examine pharmacokinetics of parent drug and metabolites in healthy subjects.Transport of xanthurenic acid by rat/human organic anion transporters OAT1 and OAT3.Pharmacokinetic interaction between methotrexate and chloral hydrate.Effects of proton pump inhibitors and famotidine on elimination of plasma methotrexate: Evaluation of drug-drug interactions mediated by organic anion transporter 3.Stereoselective inhibitory effect of flurbiprofen, ibuprofen and naproxen on human organic anion transporters hOAT1 and hOAT3.Investigation of the Importance of Multidrug Resistance-Associated Protein 4 (Mrp4/Abcc4) in the Active Efflux of Anionic Drugs Across the Blood-Brain Barrier.Concurrent use of methotrexate and celecoxib increases risk of silent liver fibrosis in rheumatoid arthritis patients with subclinical reduced kidney function.Lansoprazole Exacerbates Pemetrexed-Mediated Hematologic Toxicity by Competitive Inhibition of Renal Basolateral Human Organic Anion Transporter 3.Stereoselective Inhibition of Methotrexate Excretion by Glucuronides of Nonsteroidal Anti-inflammatory Drugs via Multidrug Resistance Proteins 2 and 4.The concomitant use of meloxicam and methotrexate does not clearly increase the risk of silent kidney and liver damages in patients with rheumatoid arthritis.
P2860
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P2860
Species difference in the inhibitory effect of nonsteroidal anti-inflammatory drugs on the uptake of methotrexate by human kidney slices.
description
2007 nî lūn-bûn
@nan
2007 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Species difference in the inhi ...... rexate by human kidney slices.
@ast
Species difference in the inhi ...... rexate by human kidney slices.
@en
Species difference in the inhi ...... rexate by human kidney slices.
@nl
type
label
Species difference in the inhi ...... rexate by human kidney slices.
@ast
Species difference in the inhi ...... rexate by human kidney slices.
@en
Species difference in the inhi ...... rexate by human kidney slices.
@nl
prefLabel
Species difference in the inhi ...... rexate by human kidney slices.
@ast
Species difference in the inhi ...... rexate by human kidney slices.
@en
Species difference in the inhi ...... rexate by human kidney slices.
@nl
P2093
P356
P1476
Species difference in the inhi ...... rexate by human kidney slices.
@en
P2093
Hayakazu Nakazawa
Hideki Nakayama
Hiroyuki Kusuhara
Masahiro Iwaki
Shigeru Horita
Teruo Okano
Tsunenori Kondo
Yoshitane Nozaki
Yoshiyuki Shiroyanagi
Yuichi Sugiyama
P304
P356
10.1124/JPET.107.121491
P407
P577
2007-06-19T00:00:00Z