Beta-lactam antibiotics induce a lethal malfunctioning of the bacterial cell wall synthesis machinery. - Wikidata - awgldk - TriplyDB

Beta-lactam antibiotics induce a lethal malfunctioning of the bacterial cell wall synthesis machinery.

Beta-lactam antibiotics induce a lethal malfunctioning of the bacterial cell wall synthesis machinery.

http://www.wikidata.org/entity/Q34645039

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Phosphorylation of the Peptidoglycan Synthase PonA1 Governs the Rate of Polar Elongation in Mycobacteria Microscale insights into pneumococcal antibiotic mutant selection windows Coarse-grained simulations of bacterial cell wall growth reveal that local coordination alone can be sufficient to maintain rod shape.Crystal structures of the transpeptidase domain of the Mycobacterium tuberculosis penicillin-binding protein PonA1 reveal potential mechanisms of antibiotic resistance Single-molecule imaging reveals modulation of cell wall synthesis dynamics in live bacterial cells Endless Resistance. Endless Antibiotics?Creating a completely "cell-free" system for protein synthesis.Structural insight into the inactivation of Mycobacterium tuberculosis non-classical transpeptidase LdtMt2 by biapenem and tebipenem.Spectral snapshots of bacterial cell-wall composition and the influence of antibiotics by whole-cell NMR.Profiling of β-lactam selectivity for penicillin-binding proteins in Escherichia coli strain DC2.Changing the narrative on antibiotics.Endopeptidase-mediated beta lactam tolerance.Coordination of peptidoglycan synthesis and outer membrane constriction during Escherichia coli cell division Avibactam and inhibitor-resistant SHV β-lactamases Antibiotic efficacy is linked to bacterial cellular respiration.A synthetic lethal approach for compound and target identification in Staphylococcus aureus Insights into the biodiversity of the gut microbiota of broiler chickens.The Listeria monocytogenes PASTA Kinase PrkA and Its Substrate YvcK Are Required for Cell Wall Homeostasis, Metabolism, and Virulence Minimal Peptidoglycan (PG) Turnover in Wild-Type and PG Hydrolase and Cell Division Mutants of Streptococcus pneumoniae D39 Growing Planktonically and in Host-Relevant Biofilms.Bacterial cell wall composition and the influence of antibiotics by cell-wall and whole-cell NMR.Loss of a Functionally and Structurally Distinct ld-Transpeptidase, LdtMt5, Compromises Cell Wall Integrity in Mycobacterium tuberculosis.Bactericidal Antibiotics Induce Toxic Metabolic Perturbations that Lead to Cellular Damage Cell Wall Recycling-Linked Coregulation of AmpC and PenB β-Lactamases through ampD Mutations in Burkholderia cenocepacia.Identification of MupP as a New Peptidoglycan Recycling Factor and Antibiotic Resistance Determinant in Pseudomonas aeruginosa.Class D β-lactamases do exist in Gram-positive bacteria.A cell wall damage response mediated by a sensor kinase/response regulator pair enables beta-lactam tolerance.Proteomic response of methicillin-resistant S. aureus to a synergistic antibacterial drug combination: a novel erythromycin derivative and oxacillin.Identification of MltG as a potential terminase for peptidoglycan polymerization in bacteria Untargeted Metabolomics To Ascertain Antibiotic Modes of Action.B1-Metallo-β-Lactamases: Where Do We Stand?Persister formation in Staphylococcus aureus is associated with ATP depletion.Novel Cephalosporins Selectively Active on Nonreplicating Mycobacterium tuberculosis.Bacterial cell wall biogenesis is mediated by SEDS and PBP polymerase families functioning semi-autonomously.Bulgecin A: The Key to a Broad-Spectrum Inhibitor That Targets Lytic Transglycosylases Deconstructing the Chlamydial Cell Wall.Hitting the sweet spot-glycans as targets of fungal defense effector proteins.LytM factors affect the recruitment of autolysins to the cell division site in Caulobacter crescentus.Lytic transglycosylases: concinnity in concision of the bacterial cell wall.Helicobacter pylori and Antibiotic Resistance, A Continuing and Intractable Problem.Antibiotic resistance in Staphylococcus aureus. Current status and future prospects.

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P2860

Beta-lactam antibiotics induce a lethal malfunctioning of the bacterial cell wall synthesis machinery.

http://www.wikidata.org/entity/Q34645039

description

2014 nî lūn-bûn

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2014 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2014 թվականի դեկտեմբերին հրատարակված գիտական հոդված

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2014年の論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年论文

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Beta-lactam antibiotics induce ...... cell wall synthesis machinery.

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Beta-lactam antibiotics induce ...... cell wall synthesis machinery.

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P356

J.CELL.2014.11.017

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Beta-lactam antibiotics induce ...... cell wall synthesis machinery.

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Hongbaek Cho

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Thomas G Bernhardt

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P2860

High resolution crystal structures of the Escherichia coli lytic transglycosylase Slt70 and its complex with a peptidoglycan fragment

Rapid beta-lactam-induced lysis requires successful assembly of the cell division machinery.

From the regulation of peptidoglycan synthesis to bacterial growth and morphology.

Challenges of antibacterial discovery

Penicillin binding protein 2 is dispensable in Escherichia coli when ppGpp synthesis is induced

The sentinel role of peptidoglycan recycling in the β-lactam resistance of the Gram-negative Enterobacteriaceae and Pseudomonas aeruginosa.

Mechanisms of action of antimicrobials: focus on fluoroquinolones.

SlmA, a nucleoid-associated, FtsZ binding protein required for blocking septal ring assembly over Chromosomes in E. coli.

Distinct penicillin binding proteins involved in the division, elongation, and shape of Escherichia coli K12.

Mechanism of action of penicillin: triggering of the pneumococcal autolytic enzyme by inhibitors of cell wall synthesis.

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6

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159

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Tsuyoshi Uehara

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25480295

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