Mechanisms of cardiovascular disease in accelerated aging syndromes.
about
DNA-dependent protein kinase (DNA-PK) permits vascular smooth muscle cell proliferation through phosphorylation of the orphan nuclear receptor NOR1A farnesyltransferase inhibitor prevents both the onset and late progression of cardiovascular disease in a progeria mouse modelExercise, Nrf2 and Antioxidant Signaling in Cardiac AgingThe role of oxidative stress and inflammation in cardiovascular agingPotential therapeutic approaches for modulating expression and accumulation of defective lamin A in laminopathies and age-related diseasesTesting the hypothesis of accelerated cerebral white matter aging in schizophrenia and major depressionTranscriptomics of cortical gray matter thickness decline during normal agingShear stress-induced mechanotransduction protein deregulation and vasculopathy in a mouse model of progeria.2014 Association of American Physicians George M. Kober Medal. Introduction of Elizabeth G. NabelLack of association of the WRN C1367T polymorphism with senile cataract in the Israeli population.Requirements for efficient proteolytic cleavage of prelamin A by ZMPSTE24.Impaired transcriptional activity of Nrf2 in age-related myocardial oxidative stress is reversible by moderate exercise training.Obligatory role for GPER in cardiovascular aging and disease.Low levels of the reverse transactivator fail to induce target transgene expression in vascular smooth muscle cellsMechanisms of premature vascular aging in children with Hutchinson-Gilford progeria syndrome.Human longevity and common variations in the LMNA gene: a meta-analysisLamins at a glance.The adventitia: a dynamic interface containing resident progenitor cells.Nuclear mechanics in diseaseCorrelated alterations in genome organization, histone methylation, and DNA-lamin A/C interactions in Hutchinson-Gilford progeria syndrome.Disruption of nuclear factor (erythroid-derived-2)-like 2 antioxidant signaling: a mechanism for impaired activation of stem cells and delayed regeneration of skeletal muscleThe Mechanobiology of AgingTelomeres and mitochondria in the aging heart.Improvement of aortic valve stenosis by ApoA-I mimetic therapy is associated with decreased aortic root and valve remodelling in miceIncreased mechanosensitivity and nuclear stiffness in Hutchinson-Gilford progeria cells: effects of farnesyltransferase inhibitorsMechanotransduction gone awry.Acute exercise stress activates Nrf2/ARE signaling and promotes antioxidant mechanisms in the myocardium.ZMPSTE24, an integral membrane zinc metalloprotease with a connection to progeroid disorders.An upregulation in the expression of vanilloid transient potential channels 2 enhances hypotonicity-induced cytosolic Ca²⁺ rise in human induced pluripotent stem cell model of Hutchinson-Gillford Progeria.Mitochondrial ferritin protects the murine myocardium from acute exhaustive exercise injury.The adventitia: a progenitor cell niche for the vessel wall.Molecular biology of atherosclerosis.Progeria, rapamycin and normal aging: recent breakthrough.Pathology of Mouse Models of Accelerated Aging.Oxidative Stress and Cardiovascular Aging: Interaction Between NRF-2 and ADMA.Aging-associated metabolic disorder induces Nox2 activation and oxidative damage of endothelial function.Vascular Aging: Implications for Cardiovascular Disease and Therapy.Cardiovascular insights from a premature aging syndrome: a translational story.Cardiac Aging - Benefits of Exercise, Nrf2 Activation and Antioxidant Signaling.Lipodystrophic syndromes due to LMNA mutations: recent developments on biomolecular aspects, pathophysiological hypotheses and therapeutic perspectives.
P2860
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P2860
Mechanisms of cardiovascular disease in accelerated aging syndromes.
description
2007 nî lūn-bûn
@nan
2007 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
name
Mechanisms of cardiovascular disease in accelerated aging syndromes.
@ast
Mechanisms of cardiovascular disease in accelerated aging syndromes.
@en
Mechanisms of cardiovascular disease in accelerated aging syndromes.
@nl
type
label
Mechanisms of cardiovascular disease in accelerated aging syndromes.
@ast
Mechanisms of cardiovascular disease in accelerated aging syndromes.
@en
Mechanisms of cardiovascular disease in accelerated aging syndromes.
@nl
prefLabel
Mechanisms of cardiovascular disease in accelerated aging syndromes.
@ast
Mechanisms of cardiovascular disease in accelerated aging syndromes.
@en
Mechanisms of cardiovascular disease in accelerated aging syndromes.
@nl
P1433
P1476
Mechanisms of cardiovascular disease in accelerated aging syndromes.
@en
P2093
Elizabeth G Nabel
P356
10.1161/CIRCRESAHA.107.153692
P577
2007-07-01T00:00:00Z