about
Regulation of proapoptotic mammalian ste20-like kinase MST2 by the IGF1-Akt pathwayWW domain-mediated interaction with Wbp2 is important for the oncogenic property of TAZTAZ promotes cell proliferation and epithelial-mesenchymal transition and is inhibited by the hippo pathwayMOBKL1A/MOBKL1B phosphorylation by MST1 and MST2 inhibits cell proliferationPhosphoinositide 3-kinase/Akt inhibits MST1-mediated pro-apoptotic signaling through phosphorylation of threonine 120TEAD mediates YAP-dependent gene induction and growth controlThe DHHC palmitoyltransferase approximated regulates Fat signaling and Dachs localization and activityThe neurofibromatosis 2 tumor suppressor gene product, merlin, regulates human meningioma cell growth by signaling through YAPMammalian Hippo signalling: a kinase network regulated by protein-protein interactionsFunctional role of Mst1/Mst2 in embryonic stem cell differentiationStructural basis of YAP recognition by TEAD4 in the Hippo pathwayStructural basis of the heterodimerization of the MST and RASSF SARAH domains in the Hippo signalling pathwayTargeting the VEGF-C/VEGFR3 axis suppresses Slug-mediated cancer metastasis and stemness via inhibition of KRAS/YAP1 signalingCerebellum development and medulloblastomaYAP1 is amplified and up-regulated in hedgehog-associated medulloblastomas and mediates Sonic hedgehog-driven neural precursor proliferationA crucial role of WW45 in developing epithelial tissues in the mouseThe Hippo Pathway Targets Rae1 to Regulate Mitosis and Organ Size and to Feed Back to Regulate Upstream Components Merlin, Hippo, and WartsCrucial role for Mst1 and Mst2 kinases in early embryonic development of the mouseSalvador-Warts-Hippo pathway in a developmental checkpoint monitoring helix-loop-helix proteins.Development and morphogenesis of the Wolffian/epididymal duct, more twists and turnsThe hippo pathway promotes Notch signaling in regulation of cell differentiation, proliferation, and oocyte polarityContext-dependent requirement for dE2F during oncogenic proliferationEnhancement of pig embryonic implants in factor VIII KO mice: a novel role for the coagulation cascade in organ size control.Genetic control of programmed cell death during animal development.Liver-specific ablation of integrin-linked kinase in mice results in enhanced and prolonged cell proliferation and hepatomegaly after phenobarbital administration.Mutual dependence of Mob1 and the chromosomal passenger complex for localization during mitosis.YAP-dependent induction of amphiregulin identifies a non-cell-autonomous component of the Hippo pathway.dMyc functions downstream of Yorkie to promote the supercompetitive behavior of hippo pathway mutant cells.Kibra is a regulator of the Salvador/Warts/Hippo signaling networkThe H3K27me3 demethylase dUTX is a suppressor of Notch- and Rb-dependent tumors in DrosophilaMammalian Ste20-like kinase (Mst2) indirectly supports Raf-1/ERK pathway activity via maintenance of protein phosphatase-2A catalytic subunit levels and consequent suppression of inhibitory Raf-1 phosphorylationGenomic profiling of advanced-stage oral cancers reveals chromosome 11q alterations as markers of poor clinical outcome.AIF downregulation and its interaction with STK3 in renal cell carcinoma.Activation of YAP1 is associated with poor prognosis and response to taxanes in ovarian cancer.Human transcriptional coactivator with PDZ-binding motif (TAZ) is downregulated during decidualization.Regulation of a LATS-homolog by Ras GTPases is important for the control of cell division.Differential NDR/LATS interactions with the human MOB family reveal a negative role for human MOB2 in the regulation of human NDR kinases.YAP1 recruits c-Abl to protect angiomotin-like 1 from Nedd4-mediated degradation.Screening of binding proteins that interact with human Salvador 1 in a human fetal liver cDNA library by the yeast two-hybrid system.Heat shock protein 90 inhibition depletes LATS1 and LATS2, two regulators of the mammalian hippo tumor suppressor pathway.
P2860
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P2860
description
2007 nî lūn-bûn
@nan
2007 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Filling out the Hippo pathway.
@ast
Filling out the Hippo pathway.
@en
Filling out the Hippo pathway.
@nl
type
label
Filling out the Hippo pathway.
@ast
Filling out the Hippo pathway.
@en
Filling out the Hippo pathway.
@nl
prefLabel
Filling out the Hippo pathway.
@ast
Filling out the Hippo pathway.
@en
Filling out the Hippo pathway.
@nl
P2860
P356
P1476
Filling out the Hippo pathway.
@en
P2093
Bruce A Edgar
Leslie J Saucedo
P2860
P2888
P304
P356
10.1038/NRM2221
P577
2007-08-01T00:00:00Z
P6179
1012452238