Activation of the mGlu7 receptor elicits antidepressant-like effects in mice.
about
The metabotropic glutamate receptor 7 (mGluR7) allosteric agonist AMN082 modulates nucleus accumbens GABA and glutamate, but not dopamine, in ratsPotential of Glutamate-Based Drug Discovery for Next Generation AntidepressantsMetabotropic Glutamate Receptor 7 (mGluR7) as a Target for the Treatment of Psychostimulant DependenceNovel loci for major depression identified by genome-wide association study of Sequenced Treatment Alternatives to Relieve Depression and meta-analysis of three studiesFunctional Dissociation of Group III Metabotropic Glutamate Receptors Revealed by Direct Comparison between the Behavioral Profiles of Knockout Mouse Lines.Blocking metabotropic glutamate receptor subtype 7 (mGlu7) via the Venus flytrap domain (VFTD) inhibits amygdala plasticity, stress, and anxiety-related behaviorAllosteric modulation of metabotropic glutamate receptors.The genetics of major depression: moving beyond the monoamine hypothesis.Open questions in current models of antidepressant action.Glutamatergic modulators: the future of treating mood disorders?Metabotropic glutamate receptor 7 modulates the rewarding effects of cocaine in rats: involvement of a ventral pallidal GABAergic mechanism.Comprehensive gene- and pathway-based analysis of depressive symptoms in older adults.Novel glutamatergic agents for major depressive disorder and bipolar disorder.Therapeutic potential of metabotropic glutamate receptor modulators.Regulation of N-methyl-D-aspartic acid (NMDA) receptors by metabotropic glutamate receptor 7mGluR7 genetics and alcohol: intersection yields clues for addiction.Functional monoclonal antibody acts as a biased agonist by inducing internalization of metabotropic glutamate receptor 7.Effects of metabotropic glutamate receptor ligands on male sexual behavior in rats.Nonselective suppression of operant ethanol and sucrose self-administration by the mGluR7 positive allosteric modulator AMN082.Metabotropic glutamate 7 (mGlu7) receptor: a target for medication development for the treatment of cocaine dependence.The Emerging Role of Metabotropic Glutamate Receptors in the Pathophysiology of Chronic Stress-Related DisordersTargeting glutamatergic signaling for the development of novel therapeutics for mood disordersTherapeutic Modulation of Glutamate Receptors in Major Depressive DisorderNovel glutamatergic drugs for the treatment of mood disorders.Supraspinal metabotropic glutamate receptors: a target for pain relief and beyond.Therapeutic potential of targeting glutamate receptors in Parkinson's disease.Progress toward advanced understanding of metabotropic glutamate receptors: structure, signaling and therapeutic indicationsMetabotropic Glutamate Receptor 7: From Synaptic Function to Therapeutic Implications.Glutamate-Based Drug Discovery for Novel Antidepressants.Metabotropic glutamate receptors: potential drug targets for psychiatric disorders.Opposing efficacy of group III mGlu receptor activators, LSP1-2111 and AMN082, in animal models of positive symptoms of schizophrenia.The frontal cortex as a network hub controlling mood and cognition: Probing its neurochemical substrates for improved therapy of psychiatric and neurological disorders.The antidepressant-like action of mGlu5 receptor antagonist, MTEP, in the tail suspension test in mice is serotonin dependent.Fasoracetam in adolescents with ADHD and glutamatergic gene network variants disrupting mGluR neurotransmitter signaling.Discovery of VU6005649, a CNS Penetrant mGlu7/8 Receptor PAM Derived from a Series of Pyrazolo[1,5-a]pyrimidines.Pharmacological modulation of mGluR7 with AMN082 and MMPIP exerts specific influences on alcohol consumption and preference in rats.Negative Allosteric Modulators of mGlu Receptor as Putative Antipsychotic Drugs
P2860
Q24645270-E89A41B8-9840-4471-9C69-548993910DC5Q26782274-0245B034-E79E-4997-825E-284148A41477Q28084494-0E4A18E8-121B-44B6-BE60-E444D7A93554Q28751388-04DBFCB8-BBE6-423A-9ACB-C95D5B6B752FQ30390870-7314947B-0A79-4DF3-8718-267F9EAD7E6BQ30414092-BDB5E8F8-E398-4AF0-802D-4F73B2D92967Q30448534-8CF7749B-7D19-42C5-9091-E8E86091C4B0Q33669125-40270CA0-F5BD-4CC6-BE10-542DD7A83367Q33767182-77B5AB68-942E-4CB5-AADE-376DD45ACEDEQ34398007-BDC5A92B-627A-45D4-8645-DD88A7AF6262Q34926511-0EC3973A-9A38-4845-80EC-5C3301D3D5A7Q35434690-907C3B0E-6109-48FE-96EA-503D1CA8E46EQ35661119-A98931F3-339A-482C-909C-CE64DFD3A416Q35778704-CD24F6EE-DEE0-45A9-9776-41F666AE9D4EQ35879968-C44F7912-91C8-4EDA-8C7B-00D40D0215C1Q36197596-6F7C25C5-7C2D-490F-B283-4B7FA12461D4Q36446506-489FBE6C-8847-4F8F-B269-EAAC7CBD07CAQ36472772-30514CD2-4CB2-4709-95B9-891975E507A2Q36925075-2961B7C9-EDDC-4EDD-8724-63F472756B24Q37103693-E015169B-8F02-4065-B8C4-13CD1E5ED3AEQ37172873-1EDC0EA9-C342-4F91-9ACA-43F816C4CB1DQ37481603-26769B1B-23BA-4903-847D-B6874ACFA585Q37668014-DDB825ED-016A-4F34-95EC-49BAD478FFEFQ38131480-025364A4-383A-4373-A9B4-71A47A5BA955Q38185074-0E60C439-17AE-424E-AE4C-82A91F0B0BEDQ38190016-E2B99AB6-7FDA-4104-ACC5-6531B72B5117Q38209092-39CB5E2B-BB66-4C93-9205-859FA4895A77Q38865953-226EFA92-E5E3-4F1A-B89F-D6A0D9AE1DE8Q38895017-3A1B6521-866F-4747-A84C-2997CF291101Q41157725-9356969D-68CD-4E42-8478-749531E308BCQ42587707-4E0238BB-BC4C-48EA-93B9-95A94F44569EQ47382890-F932EB42-0FD0-4C7F-807B-4688D47FC8E5Q47745303-1B41542D-C4C1-421A-94E0-E3356E1F469FQ48231926-BA2885A4-D92D-4E74-8BEC-471EC4325E25Q50066117-D5E319D8-37B8-4306-A824-A3B90A5EAEDAQ52298306-585EF843-B6F5-4C51-9BAF-815786FD7736Q57191778-B242B6B8-4954-4CE2-8A32-AE7BD26C8075
P2860
Activation of the mGlu7 receptor elicits antidepressant-like effects in mice.
description
2007 nî lūn-bûn
@nan
2007 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Activation of the mGlu7 receptor elicits antidepressant-like effects in mice.
@ast
Activation of the mGlu7 receptor elicits antidepressant-like effects in mice.
@en
Activation of the mGlu7 receptor elicits antidepressant-like effects in mice.
@nl
type
label
Activation of the mGlu7 receptor elicits antidepressant-like effects in mice.
@ast
Activation of the mGlu7 receptor elicits antidepressant-like effects in mice.
@en
Activation of the mGlu7 receptor elicits antidepressant-like effects in mice.
@nl
prefLabel
Activation of the mGlu7 receptor elicits antidepressant-like effects in mice.
@ast
Activation of the mGlu7 receptor elicits antidepressant-like effects in mice.
@en
Activation of the mGlu7 receptor elicits antidepressant-like effects in mice.
@nl
P2093
P2860
P50
P1433
P1476
Activation of the mGlu7 receptor elicits antidepressant-like effects in mice.
@en
P2093
Herman van der Putten
Kinga Klak
Peter J Flor
P2860
P2888
P304
P356
10.1007/S00213-007-0856-2
P577
2007-07-12T00:00:00Z
P5875
P6179
1030328215