Epithelial and dendritic cells in the thymic medulla promote CD4+Foxp3+ regulatory T cell development via the CD27-CD70 pathway
about
T cell receptor signalling in the control of regulatory T cell differentiation and functionControl of the thymic medulla and its influence on αβT-cell developmentRole of Dendritic Cells in the Induction of Lymphocyte ToleranceInfluence of maternal immunization with allergens on the thymic maturation of lymphocytes with regulatory potential in children: a broad field for further explorationTargeting the T-cell co-stimulatory CD27/CD70 pathway in cancer immunotherapy: rationale and potentialStimulating CD27 to quantitatively and qualitatively shape adaptive immunity to cancer.Dual function of CD70 in viral infection: modulator of early cytokine responses and activator of adaptive responses.Conserved and divergent aspects of human T-cell development and migration in humanized miceUnique properties of thymic antigen-presenting cells promote epigenetic imprinting of alloantigen-specific regulatory T cells.CD11c-mediated deletion of Flip promotes autoreactivity and inflammatory arthritis.Thymic regulatory T cell niche size is dictated by limiting IL-2 from antigen-bearing dendritic cells and feedback competition.The Role of Dendritic Cells in Central TolerancemTORC1 in Thymic Epithelial Cells Is Critical for Thymopoiesis, T-Cell Generation, and Temporal Control of γδT17 Development and TCRγ/δ RecombinationHuman thymus medullary epithelial cells promote regulatory T-cell generation by stimulating interleukin-2 production via ICOS ligandCharacterization of the human T cell response to in vitro CD27 costimulation with varlilumabCCR7 Controls Thymus Recirculation, but Not Production and Emigration, of Foxp3(+) T CellsmTORC2 in Thymic Epithelial Cells Controls Thymopoiesis and T Cell Development.Peripherally induced tregs - role in immune homeostasis and autoimmunityNF-κB signaling mediates homeostatic maturation of new T cells.Costimulation via the tumor-necrosis factor receptor superfamily couples TCR signal strength to the thymic differentiation of regulatory T cells.Regulations of gene expression in medullary thymic epithelial cells required for preventing the onset of autoimmune diseases.Regulatory T cells in atherosclerosis: critical immune regulatory function and therapeutic potential.ATVB Distinguished Scientist Award: How Costimulatory and Coinhibitory Pathways Shape Atherosclerosis.Therapeutic targeting of CD70 and CD27.Development of T-cell tolerance utilizes both cell-autonomous and cooperative presentation of self-antigen.Dendritic cells as gatekeepers of tolerance.CD70-restricted specific activation of TRAILR1 or TRAILR2 using scFv-targeted TRAIL mutants.The Importance of Dendritic Cells in Maintaining Immune Tolerance.Immune checkpoint proteins: exploring their therapeutic potential to regulate atherosclerosis.IL-2 and IL-15 dependent thymic development of Foxp3-expressing regulatory T lymphocytes.Host-Derived CD70 Suppresses Murine Graft-versus-Host Disease by Limiting Donor T Cell Expansion and Effector Function.Targeted alpha therapy using a novel CD70 targeted thorium-227 conjugate in in vitro and in vivo models of renal cell carcinoma.Tregs strip dendritic cells of CD70 to regulate Th1 differentiation.The phenotype and activation status of regulatory T cells during Friend retrovirus infection.CCR7 Modulates the Generation of Thymic Regulatory T Cells by Altering the Composition of the Thymic Dendritic Cell Compartment.Trial watch: Dendritic cell-based interventions for cancer therapy.A regulatory role for TGF-β signaling in the establishment and function of the thymic medulla.CD27-Mediated Regulatory T Cell Depletion and Effector T Cell Costimulation Both Contribute to Antitumor Efficacy.T Cell-Derived CD70 Delivers an Immune Checkpoint Function in Inflammatory T Cell Responses.CD40 Mediates Maturation of Thymic Dendritic Cells Driven by Self-Reactive CD4+ Thymocytes and Supports Development of Natural Regulatory T Cells.
P2860
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P2860
Epithelial and dendritic cells in the thymic medulla promote CD4+Foxp3+ regulatory T cell development via the CD27-CD70 pathway
description
2013 nî lūn-bûn
@nan
2013 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
Epithelial and dendritic cells ...... ment via the CD27-CD70 pathway
@ast
Epithelial and dendritic cells ...... ment via the CD27-CD70 pathway
@en
Epithelial and dendritic cells ...... ment via the CD27-CD70 pathway
@nl
type
label
Epithelial and dendritic cells ...... ment via the CD27-CD70 pathway
@ast
Epithelial and dendritic cells ...... ment via the CD27-CD70 pathway
@en
Epithelial and dendritic cells ...... ment via the CD27-CD70 pathway
@nl
prefLabel
Epithelial and dendritic cells ...... ment via the CD27-CD70 pathway
@ast
Epithelial and dendritic cells ...... ment via the CD27-CD70 pathway
@en
Epithelial and dendritic cells ...... ment via the CD27-CD70 pathway
@nl
P2093
P2860
P50
P356
P1476
Epithelial and dendritic cells ...... ment via the CD27-CD70 pathway
@en
P2093
Daniel J Pennington
Diogo Fonseca-Pereira
Gerda van der Horst
Jannie Borst
Joana F Neves
Nikolina Bąbała
Yanling Xiao
P2860
P304
P356
10.1084/JEM.20112061
P407
P577
2013-04-01T00:00:00Z