The MLL recombinome of acute leukemias in 2013. - Wikidata - awgldk - TriplyDB

The MLL recombinome of acute leukemias in 2013.

The MLL recombinome of acute leukemias in 2013.

http://www.wikidata.org/entity/Q34651113

about

New and emerging prognostic and predictive genetic biomarkers in B-cell precursor acute lymphoblastic leukemia Systematic Classification of Mixed-Lineage Leukemia Fusion Partners Predicts Additional Cancer Pathways Molecular landscape of acute myeloid leukemia in younger adults and its clinical relevance Revisiting the biology of infant t(4;11)/MLL-AF4+ B-cell acute lymphoblastic leukemia Pediatric AML: From Biology to Clinical Management Leukemogenic rearrangements at the mixed lineage leukemia gene (MLL)-multiple rather than a single mechanism Intrinsic protein disorder in histone lysine methylation.Acetylation Reader Proteins: Linking Acetylation Signaling to Genome Maintenance and Cancer Environmental and chemotherapeutic agents induce breakage at genes involved in leukemia-causing gene rearrangements in human hematopoietic stem/progenitor cells.Degree of recruitment of DOT1L to MLL-AF9 defines level of H3K79 Di- and tri-methylation on target genes and transformation potential.Murine models of acute leukemia: important tools in current pediatric leukemia research.Downregulation of RUNX1/CBFβ by MLL fusion proteins enhances hematopoietic stem cell self-renewal.Detection of gene rearrangements in targeted clinical next-generation sequencing.Homozygous inv(11)(q21q23) and MLL gene rearrangement in two patients with myeloid neoplasms Requirement for CDK6 in MLL-rearranged acute myeloid leukemia.Enhancers of Polycomb EPC1 and EPC2 sustain the oncogenic potential of MLL leukemia stem cells The landscape of somatic mutations in infant MLL-rearranged acute lymphoblastic leukemias The molecular mechanics of mixed lineage leukemia.The caspase-8 inhibitor emricasan combines with the SMAC mimetic birinapant to induce necroptosis and treat acute myeloid leukemia.Dynamics of double strand breaks and chromosomal translocations ARID5B polymorphism confers an increased risk to acquire specific MLL rearrangements in early childhood leukemia.A robust approach for blind detection of balanced chromosomal rearrangements with whole-genome low-coverage sequencing.Incidence of common preleukemic gene fusions in umbilical cord blood in Slovak population.Characterization and inhibition of AF10-mediated interaction.Effective targeting of the P53-MDM2 axis in preclinical models of infant MLL-rearranged acute lymphoblastic leukemia.Targeting cell cycle regulators in hematologic malignancies.Chromosomal rearrangement involving 11q23 locus in chronic myelogenous leukemia: a rare phenomenon frequently associated with disease progression and poor prognosis.BreaKmer: detection of structural variation in targeted massively parallel sequencing data using kmers.Novel Cryptic Rearrangements in Adult B-Cell Precursor Acute Lymphoblastic Leukemia Involving the MLL Gene.Use of Genome Engineering to Create Patient Specific MLL Translocations in Primary Human Hematopoietic Stem and Progenitor Cells.Targeting DOT1L and HOX gene expression in MLL-rearranged leukemia and beyond Collaborative Efforts Driving Progress in Pediatric Acute Myeloid Leukemia.CCI-007, a novel small molecule with cytotoxic activity against infant leukemia with MLL rearrangements.MLL leukemia induction by genome editing of human CD34+ hematopoietic cells.Impact of Charged Particle Exposure on Homologous DNA Double-Strand Break Repair in Human Blood-Derived Cells.AF4 uses the SL1 components of RNAP1 machinery to initiate MLL fusion- and AEP-dependent transcription.Treatment of infant leukemias: challenge and promise.Determination of ETV6-RUNX1 genomic breakpoint by next-generation sequencing.Histone demethylase KDM2B regulates lineage commitment in normal and malignant hematopoiesis.Identification of MLL-fusion/MYC⊣miR-26⊣TET1 signaling circuit in MLL-rearranged leukemia.

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The MLL recombinome of acute leukemias in 2013.

http://www.wikidata.org/entity/Q34651113

description

2013 nî lūn-bûn

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2013 թուականի Ապրիլին հրատարակուած գիտական յօդուած

@hyw

2013 թվականի ապրիլին հրատարակված գիտական հոդված

@hy

2013年の論文

@ja

2013年論文

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2013年論文

@zh-hant

2013年論文

@zh-hk

2013年論文

@zh-mo

2013年論文

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2013年论文

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name

The MLL recombinome of acute leukemias in 2013.

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The MLL recombinome of acute leukemias in 2013.

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The MLL recombinome of acute leukemias in 2013.

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type

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The MLL recombinome of acute leukemias in 2013.

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The MLL recombinome of acute leukemias in 2013.

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The MLL recombinome of acute leukemias in 2013.

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The MLL recombinome of acute leukemias in 2013.

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The MLL recombinome of acute leukemias in 2013.

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The MLL recombinome of acute leukemias in 2013.

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The MLL recombinome of acute leukemias in 2013

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A Kolenova

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A Kustanovich

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A Möricke

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A Renneville

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C Bueno

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C Eckert

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C Henry

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C Herbaux

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C M Zwaan

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C Meyer

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P2860

Protein interactions of the MLL PHD fingers modulate MLL target gene regulation in human cells.

Mouse homologue of yeast Prp19 interacts with mouse SUG1, the regulatory subunit of 26S proteasome

Molecular architecture of the human Prp19/CDC5L complex

Fusion between transcription factor CBF beta/PEBP2 beta and a myosin heavy chain in acute myeloid leukemia

Pro isomerization in MLL1 PHD3-bromo cassette connects H3K4me readout to CyP33 and HDAC-mediated repression

Interaction of U-box E3 ligase SNEV with PSMB4, the beta7 subunit of the 20 S proteasome

Cep164 is a mediator protein required for the maintenance of genomic stability through modulation of MDC1, RPA, and CHK1

MLL repression domain interacts with histone deacetylases, the polycomb group proteins HPC2 and BMI-1, and the corepressor C-terminal-binding protein

hDOT1L links histone methylation to leukemogenesis.

Transcription regulation by histone methylation: interplay between different covalent modifications of the core histone tails

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scholarly article

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10.1038/LEU.2013.135

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11

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27

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Rolf Marschalek

Stefan K. Bohlander

Manuel R. Teixeira

Theodor Dingermann

Olaf Heidenreich

Maria S Pombo-de-Oliveira

Mariana Emerenciano

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2013-04-30T00:00:00Z

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23628958

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3826032

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