Metabolism and tissue distribution of orally administered trichloroethylene in male and female rats: identification of glutathione- and cytochrome P-450-derived metabolites in liver, kidney, blood, and urine.
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Role of mitochondrial dysfunction in cellular responses to S-(1,2-dichlorovinyl)-L-cysteine in primary cultures of human proximal tubular cellsStructures of aminoacylase 3 in complex with acetylated substratesThe trichloroethylene metabolite S-(1,2-dichlorovinyl)-l-cysteine but not trichloroacetate inhibits pathogen-stimulated TNF-α in human extraplacental membranes in vitroCysteine conjugate beta-lyase activity of rat erythrocytes and formation of beta-lyase-derived globin monoadducts and cross-links after in vitro exposure of erythrocytes to S-(1,2-dichlorovinyl)-L-cysteineTransport of N-acetyl-S-(1,2-dichlorovinyl)-L-cysteine, a metabolite of trichloroethylene, by mouse multidrug resistance associated protein 2 (Mrp2).Occupational trichloroethylene exposure and renal carcinoma risk: evidence of genetic susceptibility by reductive metabolism gene variants.Interstrain differences in the liver effects of trichloroethylene in a multistrain panel of inbred miceTrichloroethylene biotransformation and its role in mutagenicity, carcinogenicity and target organ toxicity.Comparative analysis of the relationship between trichloroethylene metabolism and tissue-specific toxicity among inbred mouse strains: liver effects.Comparative analysis of the relationship between trichloroethylene metabolism and tissue-specific toxicity among inbred mouse strains: kidney effects.Modulation of hepatic and renal metabolism and toxicity of trichloroethylene and perchloroethylene by alterations in status of cytochrome P450 and glutathione.Pharmacokinetic analysis of trichloroethylene metabolism in male B6C3F1 mice: Formation and disposition of trichloroacetic acid, dichloroacetic acid, S-(1,2-dichlorovinyl)glutathione and S-(1,2-dichlorovinyl)-L-cysteine.Liquid chromatography electrospray ionization tandem mass spectrometry analysis method for simultaneous detection of trichloroacetic acid, dichloroacetic acid, S-(1,2-dichlorovinyl)glutathione and S-(1,2-dichlorovinyl)-L-cysteine.Trichloroethylene: Mechanistic, epidemiologic and other supporting evidence of carcinogenic hazard.In vivo effects of naproxen, salicylic acid, and valproic acid on the pharmacokinetics of trichloroethylene and metabolites in rats.Xenobiotic transporters and kidney injury.Inhibition of aminoacylase 3 protects rat brain cortex neuronal cells from the toxicity of 4-hydroxy-2-nonenal mercapturate and 4-hydroxy-2-nonenal.Editor's Highlight: Collaborative Cross Mouse Population Enables Refinements to Characterization of the Variability in Toxicokinetics of Trichloroethylene and Provides Genetic Evidence for the Role of PPAR Pathway in Its Oxidative Metabolism.Mechanisms of chloroform-induced hepatotoxicity: oxidative stress and mitochondrial permeability transition in freshly isolated mouse hepatocytes.Characterization of inter-tissue and inter-strain variability of TCE glutathione conjugation metabolites DCVG, DCVC, and NAcDCVC in the mouse.Racial Disparities and Preventive Measures to Renal Cell Carcinoma.
P2860
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P2860
Metabolism and tissue distribution of orally administered trichloroethylene in male and female rats: identification of glutathione- and cytochrome P-450-derived metabolites in liver, kidney, blood, and urine.
description
2006 nî lūn-bûn
@nan
2006 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Metabolism and tissue distribu ...... ver, kidney, blood, and urine.
@ast
Metabolism and tissue distribu ...... ver, kidney, blood, and urine.
@en
Metabolism and tissue distribu ...... ver, kidney, blood, and urine.
@nl
type
label
Metabolism and tissue distribu ...... ver, kidney, blood, and urine.
@ast
Metabolism and tissue distribu ...... ver, kidney, blood, and urine.
@en
Metabolism and tissue distribu ...... ver, kidney, blood, and urine.
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prefLabel
Metabolism and tissue distribu ...... ver, kidney, blood, and urine.
@ast
Metabolism and tissue distribu ...... ver, kidney, blood, and urine.
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Metabolism and tissue distribu ...... ver, kidney, blood, and urine.
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P2860
P1476
Metabolism and tissue distribu ...... ver, kidney, blood, and urine.
@en
P2093
David A Putt
Jean C Parker
P2860
P304
P356
10.1080/15287390500360133
P577
2006-07-01T00:00:00Z