Targeted expression of baculovirus p35 caspase inhibitor in oligodendrocytes protects mice against autoimmune-mediated demyelination.
about
The unfolded protein response in multiple sclerosisCovalent inhibition revealed by the crystal structure of the caspase-8/p35 complexBaculovirus infection triggers a shift from amino acid starvation-induced autophagy to apoptosisSchwann-spheres derived from injured peripheral nerves in adult mice--their in vitro characterization and therapeutic potentialImportance of oligodendrocyte protection, BBB breakdown and inflammation for remyelination.Expression of baculovirus anti-apoptotic genes p35 and op-iap in cotton (Gossypium hirsutum L.) enhances tolerance to verticillium wilt.Proteases for cell suicide: functions and regulation of caspases.The crucial role of caspase-9 in the disease progression of a transgenic ALS mouse model.Baculovirus apoptotic suppressor P49 is a substrate inhibitor of initiator caspases resistant to P35 in vivo.Mutational analyses of the p35-caspase interaction. A bowstring kinetic model of caspase inhibition by p35.Finding degrees of separation: experimental approaches for astroglial and oligodendroglial cell isolation and genetic targetingSubstrain differences reveal novel disease-modifying gene candidates that alter the clinical course of a rodent model of multiple sclerosis.Pharmaceutical integrated stress response enhancement protects oligodendrocytes and provides a potential multiple sclerosis therapeuticThe integrated stress response prevents demyelination by protecting oligodendrocytes against immune-mediated damage.Caspase-11 mediates oligodendrocyte cell death and pathogenesis of autoimmune-mediated demyelination.Harnessing the integrated stress response for the treatment of multiple sclerosis.Oligodendrocyte-specific activation of PERK signaling protects mice against experimental autoimmune encephalomyelitis.Epigenetic regulation of neural cell differentiation plasticity in the adult mammalian brainOverexpression of the dominant-negative form of interferon regulatory factor 1 in oligodendrocytes protects against experimental autoimmune encephalomyelitisBone marrow stromal cell therapy reduces proNGF and p75 expression in mice with experimental autoimmune encephalomyelitis.Caspases determine the vulnerability of oligodendrocytes in the ischemic brainNeuroprotective effects of the complement terminal pathway during demyelination: implications for oligodendrocyte survival.Myelinosome formation represents an early stage of oligodendrocyte damage in multiple sclerosis and its animal model.Creatine Enhances Mitochondrial-Mediated Oligodendrocyte Survival After Demyelinating InjuryGenetic approaches to study glial cells in the rodent brain.Molecular mechanisms of oligodendrocyte injury in multiple sclerosis and experimental autoimmune encephalomyelitis.NF-κB activation protects oligodendrocytes against inflammation.Genetic inactivation of PERK signaling in mouse oligodendrocytes: normal developmental myelination with increased susceptibility to inflammatory demyelination.A mechanism of impaired mobility of oligodendrocyte progenitor cells by tenascin C through modification of wnt signaling.Apoptotic death following Fas activation in human oligodendrocyte hybrid cultures.AMPA receptor-mediated toxicity in oligodendrocyte progenitors involves free radical generation and activation of JNK, calpain and caspase 3.Calpain and calpastatin expression in primary oligodendrocyte culture: preferential localization of membrane calpain in cell processes.Molecular mechanisms of enhanced susceptibility to apoptosis in differentiating oligodendrocytes.Activating transcription factor 6α deficiency exacerbates oligodendrocyte death and myelin damage in immune-mediated demyelinating diseases.The p35 relative, p49, inhibits mammalian and Drosophila caspases including DRONC and protects against apoptosis.Iron contributes to dopamine-induced toxicity in oligodendrocyte progenitors.
P2860
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P2860
Targeted expression of baculovirus p35 caspase inhibitor in oligodendrocytes protects mice against autoimmune-mediated demyelination.
description
2000 nî lūn-bûn
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2000 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Targeted expression of baculov ...... immune-mediated demyelination.
@ast
Targeted expression of baculov ...... immune-mediated demyelination.
@en
Targeted expression of baculov ...... immune-mediated demyelination.
@nl
type
label
Targeted expression of baculov ...... immune-mediated demyelination.
@ast
Targeted expression of baculov ...... immune-mediated demyelination.
@en
Targeted expression of baculov ...... immune-mediated demyelination.
@nl
prefLabel
Targeted expression of baculov ...... immune-mediated demyelination.
@ast
Targeted expression of baculov ...... immune-mediated demyelination.
@en
Targeted expression of baculov ...... immune-mediated demyelination.
@nl
P2093
P2860
P356
P1433
P1476
Targeted expression of baculov ...... immune-mediated demyelination.
@en
P2093
Bernard CC
Hisahara S
Miyazaki J
Sugiyama F
P2860
P304
P356
10.1093/EMBOJ/19.3.341
P407
P577
2000-02-01T00:00:00Z