CNF1-induced ubiquitylation and proteasome destruction of activated RhoA is impaired in Smurf1-/- cells
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Post-translational modification of the deubiquitinating enzyme otubain 1 modulates active RhoA levels and susceptibility to Yersinia invasionInteraction between the SifA Virulence Factor and Its Host Target SKIP Is Essential for Salmonella PathogenesisSmurf2 induces ubiquitin-dependent degradation of Smurf1 to prevent migration of breast cancer cellsProtein kinase Czeta and glycogen synthase kinase-3beta control neuronal polarity in developing rodent enteric neurons, whereas SMAD specific E3 ubiquitin protein ligase 1 promotes neurite growth but does not influence polarityPDR-1/hParkin negatively regulates the phagocytosis of apoptotic cell corpses in Caenorhabditis elegans.Comparative proteome analysis of breast cancer and adjacent normal breast tissues in human.Exploitation of eukaryotic ubiquitin signaling pathways by effectors translocated by bacterial type III and type IV secretion systemsCNF1 increases brain energy level, counteracts neuroinflammatory markers and rescues cognitive deficits in a murine model of Alzheimer's disease.Cytotoxic necrotizing factor 1 prevents apoptosis via the Akt/IkappaB kinase pathway: role of nuclear factor-kappaB and Bcl-2The GTPase-deficient Rnd proteins are stabilized by their effectors.Rho GTPase-activating bacterial toxins: from bacterial virulence regulation to eukaryotic cell biology.Transforming growth factor-beta signaling and ubiquitinators in cancer.Ubiquitination: Added complexity in Ras and Rho family GTPase function.Ubiquitin links to cytoskeletal dynamics, cell adhesion and migration.Rho GTPase signaling in the development of colorectal cancer.Ubiquitylation of active Rac1 by the E3 ubiquitin-ligase HACE1.Cell cycle regulation of Rho signaling pathways.The cytotoxic necrotizing factor 1 from E. coli: a janus toxin playing with cancer regulators.The E. coli CNF1 as a pioneering therapy for the central nervous system diseases.New Aspects on Bacterial Effectors Targeting Rho GTPases.Activation of RhoA,B,C by Yersinia Cytotoxic Necrotizing Factor (CNFy) induces apoptosis in LNCaP prostate cancer cells.Rac1 acts in conjunction with Nedd4 and dishevelled-1 to promote maturation of cell-cell contacts.Escherichia coli producing CNF1 toxin hijacks Tollip to trigger Rac1-dependent cell invasion.Activated Rac1, but not the tumorigenic variant Rac1b, is ubiquitinated on Lys 147 through a JNK-regulated process.The Rho family member RhoE interacts with Skp2 and is degraded at the proteasome during cell cycle progression.Identification of cancer-associated missense mutations in hace1 that impair cell growth control and Rac1 ubiquitylation.Prenylation of Rho G-proteins: a novel mechanism regulating gene expression and protein stability in human trabecular meshwork cells.Clathrin regulates lymphocyte migration by driving actin accumulation at the cellular leading edge.
P2860
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P2860
CNF1-induced ubiquitylation and proteasome destruction of activated RhoA is impaired in Smurf1-/- cells
description
2006 nî lūn-bûn
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2006 թուականի Մարտին հրատարակուած գիտական յօդուած
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2006 թվականի մարտին հրատարակված գիտական հոդված
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2006年の論文
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2006年論文
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2006年論文
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2006年論文
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2006年論文
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2006年論文
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2006年论文
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name
CNF1-induced ubiquitylation an ...... is impaired in Smurf1-/- cells
@ast
CNF1-induced ubiquitylation an ...... is impaired in Smurf1-/- cells
@en
CNF1-induced ubiquitylation an ...... is impaired in Smurf1-/- cells
@nl
type
label
CNF1-induced ubiquitylation an ...... is impaired in Smurf1-/- cells
@ast
CNF1-induced ubiquitylation an ...... is impaired in Smurf1-/- cells
@en
CNF1-induced ubiquitylation an ...... is impaired in Smurf1-/- cells
@nl
prefLabel
CNF1-induced ubiquitylation an ...... is impaired in Smurf1-/- cells
@ast
CNF1-induced ubiquitylation an ...... is impaired in Smurf1-/- cells
@en
CNF1-induced ubiquitylation an ...... is impaired in Smurf1-/- cells
@nl
P2093
P2860
P50
P356
P1476
CNF1-induced ubiquitylation an ...... is impaired in Smurf1-/- cells
@en
P2093
Gilles Flatau
Jacques Bertoglio
Jean-Louis Mege
Laurent Turchi
Motozo Yamashita
Patrice Boquet
P2860
P304
P356
10.1091/MBC.E05-09-0876
P577
2006-03-15T00:00:00Z