SHMT1 knockdown induces apoptosis in lung cancer cells by causing uracil misincorporation.
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MicroRNAs and oncogenic transcriptional regulatory networks controlling metabolic reprogramming in cancersHow pyridoxal 5'-phosphate differentially regulates human cytosolic and mitochondrial serine hydroxymethyltransferase oligomeric stateThe Use of Chemical-Chemical Interaction and Chemical Structure to Identify New Candidate Chemicals Related to Lung CancerSerine hydroxymethyl transferase 1 stimulates pro-oncogenic cytokine expression through sialic acid to promote ovarian cancer tumor growth and progressionPositive correlation between expression level of mitochondrial serine hydroxymethyltransferase and breast cancer grade.Prognostic and therapeutic value of mitochondrial serine hydroxyl-methyltransferase 2 as a breast cancer biomarkermiR-198 targets SHMT1 to inhibit cell proliferation and enhance cell apoptosis in lung adenocarcinoma.c-Myc targeted regulators of cell metabolism in a transgenic mouse model of papillary lung adenocarcinomaDownregulating serine hydroxymethyltransferase 2 (SHMT2) suppresses tumorigenesis in human hepatocellular carcinoma.A pyrazolopyran derivative preferentially inhibits the activity of human cytosolic serine hydroxymethyltransferase and induces cell death in lung cancer cells.Alterations in cellular metabolism triggered by URA7 or GLN3 inactivation cause imbalanced dNTP pools and increased mutagenesis.Screening and in vitro testing of antifolate inhibitors of human cytosolic serine hydroxymethyltransferase.
P2860
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P2860
SHMT1 knockdown induces apoptosis in lung cancer cells by causing uracil misincorporation.
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2014 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
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SHMT1 knockdown induces apopto ...... using uracil misincorporation.
@ast
SHMT1 knockdown induces apopto ...... using uracil misincorporation.
@en
SHMT1 knockdown induces apopto ...... using uracil misincorporation.
@nl
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label
SHMT1 knockdown induces apopto ...... using uracil misincorporation.
@ast
SHMT1 knockdown induces apopto ...... using uracil misincorporation.
@en
SHMT1 knockdown induces apopto ...... using uracil misincorporation.
@nl
prefLabel
SHMT1 knockdown induces apopto ...... using uracil misincorporation.
@ast
SHMT1 knockdown induces apopto ...... using uracil misincorporation.
@en
SHMT1 knockdown induces apopto ...... using uracil misincorporation.
@nl
P2860
P50
P356
P1476
SHMT1 knockdown induces apoptosis in lung cancer cells by causing uracil misincorporation
@en
P2093
A Fiascarelli
A Paiardini
P2860
P356
10.1038/CDDIS.2014.482
P577
2014-11-20T00:00:00Z