TRPM2 channel deficiency prevents delayed cytosolic Zn2+ accumulation and CA1 pyramidal neuronal death after transient global ischemia
about
Detrimental or beneficial: the role of TRPM2 in ischemia/reperfusion injuryTRPM2 Channel-Mediated ROS-Sensitive Ca(2+) Signaling Mechanisms in Immune CellsA dual role of transient receptor potential melastatin 2 channel in cytotoxicity induced by silica nanoparticles.Non-NMDAR neuronal Ca(2+)-permeable channels in delayed neuronal death and as potential therapeutic targets for ischemic brain damage.P450 Eicosanoids and Reactive Oxygen Species Interplay in Brain Injury and Neuroprotection.Identification of the ADPR binding pocket in the NUDT9 homology domain of TRPM2.Signalling mechanisms mediating Zn2+-induced TRPM2 channel activation and cell death in microglial cells.A critical role of TRPM2 channel in Aβ42 -induced microglial activation and generation of tumor necrosis factor-α.Alteration in Intracellular Zn2+ Homeostasis as a Result of TRPM2 Channel Activation Contributes to ROS-Induced Hippocampal Neuronal Death.Selective inhibition of TRPM2 channel by two novel synthesized ADPR analogues.Pre-treated Populus tomentiglandulosa extract inhibits neuronal loss and alleviates gliosis in the gerbil hippocampal CA1 area induced by transient global cerebral ischemia.Multiple molecular mechanisms form a positive feedback loop driving amyloid β42 peptide-induced neurotoxicity via activation of the TRPM2 channel in hippocampal neurons.The role of TRPM2 channels in neurons, glial cells and the blood-brain barrier in cerebral ischemia and hypoxia.TRPM2: a candidate therapeutic target for treating neurological diseases.Identification of a Novel EF-Loop in the N-terminus of TRPM2 Channel Involved in Calcium Sensitivity.
P2860
Q26771363-4D2C13F0-3965-42B9-A50E-91D6C860B8BDQ26795462-4DF489A8-383B-4004-ABBE-118169DF7439Q36364098-DA3FE244-6426-42ED-BBC7-70C2124023CEQ38366936-93327FD8-4E5A-4874-829D-C263A6411E92Q38744600-DC1ECCC6-22AC-418F-BF5F-A9E3D6426CFFQ42216129-D1298025-0F91-4736-A269-C8251E38BCEFQ42315017-29B852A0-4756-41E4-BF95-8B8600B4C0B4Q46260569-DDBC411D-71D8-4A05-AEE8-DD528EDE6A27Q47335331-389795B6-795F-416B-AC31-9E47D7311E61Q48184032-65171E4B-D9B8-4367-9B3B-720028334739Q49892292-B2F8ABE8-04AB-4DDD-89E9-5DACBBD5D531Q50130119-A085DBD2-7D7B-45A5-AFC0-D780834999A8Q52354765-EE1308E8-7C86-4B9D-B826-2DE059D499BAQ52578572-71FE8A05-7B5E-498B-AF49-FCF0D4DCE541Q55245338-2913D847-C663-40F6-8ED8-4197455D219A
P2860
TRPM2 channel deficiency prevents delayed cytosolic Zn2+ accumulation and CA1 pyramidal neuronal death after transient global ischemia
description
2014 nî lūn-bûn
@nan
2014 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年学术文章
@wuu
2014年学术文章
@zh-cn
2014年学术文章
@zh-hans
2014年学术文章
@zh-my
2014年学术文章
@zh-sg
2014年學術文章
@yue
name
TRPM2 channel deficiency preve ...... fter transient global ischemia
@ast
TRPM2 channel deficiency preve ...... fter transient global ischemia
@en
TRPM2 channel deficiency preve ...... fter transient global ischemia
@en-gb
TRPM2 channel deficiency preve ...... fter transient global ischemia
@nl
type
label
TRPM2 channel deficiency preve ...... fter transient global ischemia
@ast
TRPM2 channel deficiency preve ...... fter transient global ischemia
@en
TRPM2 channel deficiency preve ...... fter transient global ischemia
@en-gb
TRPM2 channel deficiency preve ...... fter transient global ischemia
@nl
prefLabel
TRPM2 channel deficiency preve ...... fter transient global ischemia
@ast
TRPM2 channel deficiency preve ...... fter transient global ischemia
@en
TRPM2 channel deficiency preve ...... fter transient global ischemia
@en-gb
TRPM2 channel deficiency preve ...... fter transient global ischemia
@nl
P2093
P2860
P50
P356
P1154
2-s2.0-84927920574
P1476
TRPM2 channel deficiency preve ...... fter transient global ischemia
@en
P2093
P2860
P2888
P356
10.1038/CDDIS.2014.494
P5530
P577
2014-11-27T00:00:00Z
P5875
P6179
1031754975