Evolutionary triage governs fitness in driver and passenger mutations and suggests targeting never mutations.
about
Single-Cell Sequencing Technology in Oncology: Applications for Clinical Therapies and ResearchToward an evolutionary model of cancer: Considering the mechanisms that govern the fate of somatic mutationsNeuroblastoma, a Paradigm for Big Data Science in Pediatric Oncology.Pediatric phase I trial of oral sorafenib and topotecan in refractory or recurrent pediatric solid malignancies.Assessment of Esophageal Adenocarcinoma Risk Using Somatic Chromosome Alterations in Longitudinal Samples in Barrett's EsophagusCoGAPS matrix factorization algorithm identifies transcriptional changes in AP-2alpha target genes in feedback from therapeutic inhibition of the EGFR network.An Atlas of the Human Kinome Reveals the Mutational Landscape Underlying Dysregulated Phosphorylation Cascades in Cancer.Determinants of Genetic Diversity of Spontaneous Drug Resistance in BacteriaExploiting evolutionary principles to prolong tumor control in preclinical models of breast cancer.Cooperative genomic alteration network reveals molecular classification across 12 major cancer types.The helicase-like transcription factor (HLTF) in cancer: loss of function or oncomorphic conversion of a tumor suppressor?Genetic load makes cancer cells more sensitive to common drugs: evidence from Cancer Cell Line Encyclopedia.Defining Cancer Subpopulations by Adaptive Strategies Rather Than Molecular Properties Provides Novel Insights into Intratumoral Evolution.Evolutionary dynamics and significance of multiple subclonal mutations in cancer.Mutations, evolution and the central role of a self-defined fitness function in the initiation and progression of cancer.Machine Learning-Assisted Network Inference Approach to Identify a New Class of Genes that Coordinate the Functionality of Cancer NetworksDarwinian Dynamics of Intratumoral Heterogeneity: Not Solely Random Mutations but Also Variable Environmental Selection Forces.Classifying the evolutionary and ecological features of neoplasms.Comprehensive high-throughput image analysis for therapeutic efficacy of architecturally complex heterotypic organoids.Targeted deep sequencing of circulating tumor DNA in metastatic pancreatic cancer.
P2860
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P2860
Evolutionary triage governs fitness in driver and passenger mutations and suggests targeting never mutations.
description
2014 nî lūn-bûn
@nan
2014 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Evolutionary triage governs fi ...... sts targeting never mutations.
@ast
Evolutionary triage governs fi ...... sts targeting never mutations.
@en
Evolutionary triage governs fi ...... sts targeting never mutations.
@nl
type
label
Evolutionary triage governs fi ...... sts targeting never mutations.
@ast
Evolutionary triage governs fi ...... sts targeting never mutations.
@en
Evolutionary triage governs fi ...... sts targeting never mutations.
@nl
prefLabel
Evolutionary triage governs fi ...... sts targeting never mutations.
@ast
Evolutionary triage governs fi ...... sts targeting never mutations.
@en
Evolutionary triage governs fi ...... sts targeting never mutations.
@nl
P2860
P356
P1476
Evolutionary triage governs fi ...... ests targeting never mutations
@en
P2093
R A Gatenby
P2860
P2888
P356
10.1038/NCOMMS6499
P407
P577
2014-11-19T00:00:00Z
P5875
P6179
1000569751