The H3K9 methyltransferase G9a is a marker of aggressive ovarian cancer that promotes peritoneal metastasis.
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Functional Role of G9a Histone Methyltransferase in CancerDiscovery of first-in-class reversible dual small molecule inhibitors against G9a and DNMTs in hematological malignancies.G9A promotes tumor cell growth and invasion by silencing CASP1 in non-small-cell lung cancer cells.G9a is essential for EMT-mediated metastasis and maintenance of cancer stem cell-like characters in head and neck squamous cell carcinomaNovel Function of Lysine Methyltransferase G9a in the Regulation of Sox2 Protein StabilityThe histone methyltransferase DOT1L: regulatory functions and a cancer therapy target.A Tox21 Approach to Altered Epigenetic Landscapes: Assessing Epigenetic Toxicity Pathways Leading to Altered Gene Expression and Oncogenic Transformation In VitroAssociation of Histone Methyltransferase G9a and Overall Survival After Liver Resection of Patients With Hepatocellular Carcinoma With a Median Observation of 40 MonthsRole of several histone lysine methyltransferases in tumor development.G9a promotes proliferation and inhibits cell cycle exit during myogenic differentiation.Inhibition of EHMT2/G9a epigenetically increases the transcription of Beclin-1 via an increase in ROS and activation of NF-κB.Epigenetics in cancer stem cells.The histone methyltransferase G9a as a therapeutic target to override gemcitabine resistance in pancreatic cancer.Dysregulation of histone methyltransferases in breast cancer - Opportunities for new targeted therapies?A drive in SUVs: From development to disease.Writing, erasing and reading histone lysine methylations.G9a histone methyltransferase inhibitor BIX01294 promotes expansion of adult cardiac progenitor cells without changing their phenotype or differentiation potential.Epigenetic regulation of starvation-induced autophagy in Drosophila by histone methyltransferase G9a.Hypoxia-induced ANGPTL4 sustains tumour growth and anoikis resistance through different mechanisms in scirrhous gastric cancer cell lines.Methyltransferase G9a promotes cervical cancer angiogenesis and decreases patient survival.Epigenetic therapy with inhibitors of histone methylation suppresses DNA damage signaling and increases glioma cell radiosensitivityc-kit Positive Cardiac Outgrowth Cells Demonstrate Better Ability for Cardiac Recovery Against Ischemic Myopathy.Inhibition of the H3K9 methyltransferase G9A attenuates oncogenicity and activates the hypoxia signaling pathway.G9A promotes gastric cancer metastasis by upregulating ITGB3 in a SET domain-independent manner.SATB2 suppresses non-small cell lung cancer invasiveness by G9a.G9a/RelB regulates self-renewal and function of colon-cancer-initiating cells by silencing Let-7b and activating the K-RAS/β-catenin pathway.E4BP4/NFIL3 modulates the epigenetically repressed RAS effector RASSF8 function through histone methyltransferases.BIX-01294 sensitizes renal cancer Caki cells to TRAIL-induced apoptosis through downregulation of survivin expression and upregulation of DR5 expression.Dual Inhibition of DNA and Histone Methyltransferases Increases Viral Mimicry in Ovarian Cancer Cells
P2860
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P2860
The H3K9 methyltransferase G9a is a marker of aggressive ovarian cancer that promotes peritoneal metastasis.
description
2014 nî lūn-bûn
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2014 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի օգոստոսին հրատարակված գիտական հոդված
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2014年の論文
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2014年論文
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2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
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2014年论文
@wuu
name
The H3K9 methyltransferase G9a ...... romotes peritoneal metastasis.
@ast
The H3K9 methyltransferase G9a ...... romotes peritoneal metastasis.
@en
The H3K9 methyltransferase G9a ...... romotes peritoneal metastasis.
@nl
type
label
The H3K9 methyltransferase G9a ...... romotes peritoneal metastasis.
@ast
The H3K9 methyltransferase G9a ...... romotes peritoneal metastasis.
@en
The H3K9 methyltransferase G9a ...... romotes peritoneal metastasis.
@nl
prefLabel
The H3K9 methyltransferase G9a ...... romotes peritoneal metastasis.
@ast
The H3K9 methyltransferase G9a ...... romotes peritoneal metastasis.
@en
The H3K9 methyltransferase G9a ...... romotes peritoneal metastasis.
@nl
P2093
P2860
P50
P356
P1433
P1476
The H3K9 methyltransferase G9a ...... promotes peritoneal metastasis
@en
P2093
Chi-Kuan Chen
Ching-Huai Ko
Min-Wei Chen
Ming-Yang Wang
Pi-Lin Sung
Yi-Hua Jan
P2860
P2888
P356
10.1186/1476-4598-13-189
P577
2014-08-12T00:00:00Z
P5875
P6179
1032693197