Paclitaxel-induced apoptosis is BAK-dependent, but BAX and BIM-independent in breast tumor. - Wikidata - awgldk - TriplyDB

Paclitaxel-induced apoptosis is BAK-dependent, but BAX and BIM-independent in breast tumor.

Paclitaxel-induced apoptosis is BAK-dependent, but BAX and BIM-independent in breast tumor.

http://www.wikidata.org/entity/Q34663927

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Targeting the Mitotic Catastrophe Signaling Pathway in Cancer High Bak Expression Is Associated with a Favorable Prognosis in Breast Cancer and Sensitizes Breast Cancer Cells to Paclitaxel The NOXA-MCL1-BIM axis defines lifespan on extended mitotic arrest High glucose induces apoptosis via upregulation of Bim expression in proximal tubule epithelial cells.A Bim-targeting strategy overcomes adaptive bortezomib resistance in myeloma through a novel link between autophagy and apoptosis Overexpression of 4EBP1, p70S6K, Akt1 or Akt2 differentially promotes Coxsackievirus B3-induced apoptosis in HeLa cells.The combination of thioxodihydroquinazolinones and platinum drugs reverses platinum resistance in tumor cells by inducing mitochondrial apoptosis independent of Bax and Bak Stress hormones reduce the efficacy of paclitaxel in triple negative breast cancer through induction of DNA damage Fentanyl Enhances Hepatotoxicity of Paclitaxel via Inhibition of CYP3A4 and ABCB1 Transport Activity in Mice.Geridonin and paclitaxel act synergistically to inhibit the proliferation of gastric cancer cells through ROS-mediated regulation of the PTEN/PI3K/Akt pathway Knockdown of NF-κB p65 subunit expression suppresses growth of nude mouse lung tumour cell xenografts by inhibition of Bcl-2 apoptotic pathway.Mitochondrial estrogen receptor β inhibits cell apoptosis via interaction with Bad in a ligand-independent manner.Assessment of HTLV-1 proviral load, LAT, BIM, c-FOS and RAD51 gene expression in adult T cell leukemia/lymphoma.Perturbing mitosis for anti-cancer therapy: is cell death the only answer?Paclitaxel inhibits breast cancer metastasis via suppression of Aurora kinase-mediated cofilin-1 activity.BAK is a predictive and prognostic biomarker for the therapeutic effect of docetaxel treatment in patients with advanced gastric cancer.Neuroglobin overexpression induced by the 17β-Estradiol-Estrogen receptor-α Pathway reduces the sensitivity of MCF-7 Breast cancer cell to paclitaxel.Anti-mitotic chemotherapeutics promote apoptosis through TL1A-activated death receptor 3 in cancer cells.

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P2860

Paclitaxel-induced apoptosis is BAK-dependent, but BAX and BIM-independent in breast tumor.

http://www.wikidata.org/entity/Q34663927

description

2013 nî lūn-bûn

@nan

2013 թուականի Ապրիլին հրատարակուած գիտական յօդուած

@hyw

2013 թվականի ապրիլին հրատարակված գիտական հոդված

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2013年の論文

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2013年論文

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2013年論文

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name

Paclitaxel-induced apoptosis i ...... M-independent in breast tumor.

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Paclitaxel-induced apoptosis i ...... M-independent in breast tumor.

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Paclitaxel-induced apoptosis i ...... M-independent in breast tumor.

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type

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Paclitaxel-induced apoptosis i ...... M-independent in breast tumor.

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Paclitaxel-induced apoptosis i ...... M-independent in breast tumor.

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Paclitaxel-induced apoptosis i ...... M-independent in breast tumor.

@nl

prefLabel

Paclitaxel-induced apoptosis i ...... M-independent in breast tumor.

@ast

Paclitaxel-induced apoptosis i ...... M-independent in breast tumor.

@en

Paclitaxel-induced apoptosis i ...... M-independent in breast tumor.

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Paclitaxel-induced apoptosis i ...... M-independent in breast tumor.

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Amanda C Richardson

http://www.w3.org/2001/XMLSchema#string

Anna V Miller

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Hisashi Harada

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Mark A Hicks

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Wataru Nakajima

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P2860

Proapoptotic Bak is sequestered by Mcl-1 and Bcl-xL, but not Bcl-2, until displaced by BH3-only proteins.

Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene

Untangling the ErbB signalling network

FoxO3a transcriptional regulation of Bim controls apoptosis in paclitaxel-treated breast cancer cell lines

Microtubules as a target for anticancer drugs

Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death

The mitochondrial protein Bak is pivotal for gliotoxin-induced apoptosis and a critical host factor of Aspergillus fumigatus virulence in mice

Essential role of BAX,BAK in B cell homeostasis and prevention of autoimmune disease

The BCL-2 protein family: opposing activities that mediate cell death

Phosphate-binding tag, a new tool to visualize phosphorylated proteins

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