about
Animal models of polyglutamine diseases and therapeutic approachesNeural and mesenchymal stem cells in animal models of Huntington's disease: past experiences and future challengesElectromagnetic fields, oxidative stress, and neurodegenerationESC-Derived BDNF-Overexpressing Neural Progenitors Differentially Promote Recovery in Huntington's Disease Models by Enhanced Striatal DifferentiationBrain Diffusivity and Structural Changes in the R6/2 Mouse Model of Huntington Disease.Magnetic resonance imaging of Huntington's disease: preparing for clinical trials.Developmental Whole Brain White Matter Alterations in Transgenic Huntington's Disease Monkey.Exercise is not beneficial and may accelerate symptom onset in a mouse model of Huntington's diseaseDifferential vulnerability of neurons in Huntington's disease: the role of cell type-specific features.A rat model of striatonigral degeneration generated by simultaneous injection of 6-hydroxydopamine into the medial forebrain bundle and quinolinic acid into the striatum.POTENTIAL APPLICATION OF GRAPE DERIVED POLYPHENOLS IN HUNTINGTON'S DISEASEHigh throughput screening for inhibitors of REST in neural derivatives of human embryonic stem cells reveals a chemical compound that promotes expression of neuronal genes.Glycogen accumulation in cardiomyocytes and cardiotoxic effects after 3NPA treatmentSpatiotemporal mapping of brain atrophy in mouse models of Huntington's disease using longitudinal in vivo magnetic resonance imaging.Analysis of YFP(J16)-R6/2 reporter mice and postmortem brains reveals early pathology and increased vulnerability of callosal axons in Huntington's disease.Novel BAC Mouse Model of Huntington's Disease with 225 CAG Repeats Exhibits an Early Widespread and Stable Degenerative Phenotype.Characterization of neurophysiological and behavioral changes, MRI brain volumetry and 1H MRS in zQ175 knock-in mouse model of Huntington's disease.Allelic series of Huntington's disease knock-in mice reveals expression discorrelates.Large animal models of neurological disorders for gene therapy.Animal models for target diseases in gene therapy--using DNA and siRNA delivery strategies.Mitochondria and Huntington's disease pathogenesis: insight from genetic and chemical models.Lithium chloride could aggravate brain injury caused by 3-nitropropionic acid.Original Research: Feasibility and safety of two surgical techniques for the development of an animal model of jugular vein occlusionDopamine and glutamate in Huntington's disease: A balancing act.Lentiviral vector-mediated gene transfer and RNA silencing technology in neuronal dysfunctions.Stem cell-based therapy for Huntington's disease.Do glial cells play an anti-oxidative role in Huntington's disease?Dopamine and Huntington's disease.Mutant Huntingtin and Elusive Defects in Oxidative Metabolism and Mitochondrial Calcium Handling.AAV5-miHTT gene therapy demonstrates suppression of mutant huntingtin aggregation and neuronal dysfunction in a rat model of Huntington's disease.Huntington's Disease: Relationship Between Phenotype and Genotype.Viral vector-based tools advance knowledge of basal ganglia anatomy and physiology.The Role of Cathepsin D in the Pathogenesis of Human Neurodegenerative Disorders.Bridging the gap: large animal models in neurodegenerative research.Succinobucol, a Lipid-Lowering Drug, Protects Against 3-Nitropropionic Acid-Induced Mitochondrial Dysfunction and Oxidative Stress in SH-SY5Y Cells via Upregulation of Glutathione Levels and Glutamate Cysteine Ligase Activity.Cognitive dysfunction in Huntington's disease: mechanisms and therapeutic strategies beyond BDNF.Cytoskeleton as a Target of Quinolinic Acid Neurotoxicity: Insight from Animal Models.Restoration of the striatal circuitry: from developmental aspects toward clinical applications.Protective Effect of Spermidine Against Excitotoxic Neuronal Death Induced by Quinolinic Acid in Rats: Possible Neurotransmitters and Neuroinflammatory Mechanism.Moving toward a gene therapy for Huntington's disease.
P2860
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P2860
description
2007 nî lūn-bûn
@nan
2007 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Animal models of Huntington's disease.
@ast
Animal models of Huntington's disease.
@en
Animal models of Huntington's disease.
@nl
type
label
Animal models of Huntington's disease.
@ast
Animal models of Huntington's disease.
@en
Animal models of Huntington's disease.
@nl
prefLabel
Animal models of Huntington's disease.
@ast
Animal models of Huntington's disease.
@en
Animal models of Huntington's disease.
@nl
P2860
P356
P1433
P1476
Animal models of Huntington's disease.
@en
P2093
Jodi L McBride
Shilpa Ramaswamy
P2860
P304
P356
10.1093/ILAR.48.4.356
P577
2007-01-01T00:00:00Z